Product image of Levetiracetam Heumann (Levetiracetam) supplied by GNH India

Levetiracetam Heumann

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Heumann (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Heumann, is an antiepileptic presented as an oral dosage form for oral use. It treats epilepsy, including partial seizures and generalized tonic‑clonic seizures, in both adult and pediatric patients.

GNH India supplies Levetiracetam Heumann as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Heumann Pharma Gmbh & Co. Generica Kg

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Indications & Clinical Uses

  • Levetiracetam is an antiepileptic medication used to control seizure activity across several epilepsy syndromes.
  • Epilepsy: reduces the frequency and severity of seizures in patients with various epilepsy types.
  • Partial seizures: provides effective control of focal onset seizures, with or without secondary generalization.
  • Generalized tonic‑clonic seizures: helps prevent the occurrence of bilateral convulsive seizures in appropriate patients.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilising neuronal membranes. This action reduces abnormal neuronal firing and lowers overall brain excitability, thereby decreasing the likelihood of seizure generation.

Side Effects

Levetiracetam may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Dizziness: transient sensation of light‑headedness.
  • Fatigue: generalized tiredness or lack of energy.
  • Headache: mild to moderate cranial pain.
  • Somnolence: increased sleepiness, especially after dose initiation.
  • Nausea: occasional upset stomach.
  • Irritability: mood changes or mild agitation.

Serious or Rare Side Effects

  • Severe rash or Stevens‑Johnson syndrome: requires immediate medical attention.
  • Suicidal thoughts or behavior: monitor for mood changes.
  • Acute hypersensitivity reactions: including angioedema or anaphylaxis.
  • Hematologic abnormalities: such as thrombocytopenia or leukopenia.

Precautions & Warnings

  • Before initiating therapy, clinicians should consider several safety factors.
  • Renal function: assess and adjust dose in patients with impaired clearance.
  • Hepatic function: monitor liver enzymes in patients with liver disease.
  • Psychiatric symptoms: watch for mood swings, depression, or aggression.
  • Driving and operating machinery: advise caution due to possible drowsiness.
  • Pregnancy: safety not established; evaluate risk‑benefit with prescriber.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Levetiracetam can interact with other medicines, altering its effectiveness or safety.

Major Interactions (Avoid)

  • Carbamazepine: may significantly reduce levetiracetam plasma concentrations.
  • Phenobarbital: can lower levetiracetam levels, potentially decreasing seizure control.

Moderate Interactions (Monitor Closely)

  • Alcohol: may enhance central nervous system depression and increase dizziness.
  • Other antiepileptics (e.g., valproate, phenytoin): may require dose adjustments based on clinical response.
  • Oral contraceptives: levetiracetam may reduce hormonal efficacy, necessitating additional contraceptive measures.

Frequently Asked Questions

Levetiracetam Heumann is prescribed to manage epilepsy, specifically to control partial (focal) seizures and generalized tonic‑clonic seizures. It helps reduce the frequency and intensity of seizure episodes in patients diagnosed with these seizure types.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. By stabilising neuronal firing and decreasing excessive excitability, it lowers the likelihood of seizure generation across the brain.

The dosage of levetiracetam is individualized by the prescribing clinician based on the patient’s age, weight, renal function, and seizure type. The prescriber determines the appropriate starting dose and any subsequent adjustments.

Safety data for levetiracetam in pregnancy and lactation are limited. Clinicians should weigh potential benefits against unknown risks and discuss options with the patient. Breastfeeding decisions should also be made in consultation with a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levetiracetam offers a distinct mechanism by targeting SV2A, which differs from sodium‑channel blockers like carbamazepine. It generally has fewer drug‑enzyme interactions, a favorable pharmacokinetic profile, and is often chosen when patients experience side effects or interactions with other antiepileptics.

Levetiracetam should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and extreme heat to maintain stability and potency.

Levetiracetam is taken orally, usually as a tablet or oral solution, with or without food. The exact route (tablet versus liquid) depends on the formulation supplied, and patients should follow the prescriber’s instructions for timing and frequency.

Serious adverse events include severe skin reactions such as Stevens‑Johnson syndrome, suicidal thoughts or behaviors, and rare hematologic abnormalities. Patients should be instructed to seek immediate medical attention if they notice rash, mood changes, or unexplained bruising or bleeding.

Levetiracetam is contraindicated in individuals with known hypersensitivity to the drug or any of its excipients. Caution is advised for patients with severe renal impairment, as dose adjustment may be required, and for those with a history of psychiatric disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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