Product image of Levetiracetam Hospira (Levetiracetam) supplied by GNH India

Levetiracetam Hospira

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Hospira (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Hospira, is an antiepileptic presented as an intravenous solution for intravenous use. It treats epilepsy and seizure disorders in patients who require parenteral therapy.

GNH India supplies Levetiracetam Hospira as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Pfizer Europe Ma Eeig

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Indications & Clinical Uses

Levetiracetam is an antiepileptic drug used to control various seizure types. It is administered intravenously in clinical settings for rapid seizure control.

  • Epilepsy: reduces the frequency of both focal and generalized seizures.
  • Partial (focal) seizures: helps achieve seizure freedom when oral therapy is not feasible.
  • Generalized tonic‑clonic seizures: provides rapid control of convulsive episodes.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal membranes. This action reduces neuronal excitability and suppresses the propagation of seizure activity across the central nervous system.

Side Effects

Levetiracetam may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Dizziness: transient sensation of light‑headedness.
  • Somnolence: increased sleepiness or fatigue.
  • Headache: mild to moderate cranial pain.
  • Nausea: occasional gastrointestinal upset.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Stevens‑Johnson syndrome: rare skin blistering condition.
  • Suicidal thoughts: emergence of depressive or suicidal ideation.
  • Blood dyscrasias: rare cases of neutropenia or thrombocytopenia.

Precautions & Warnings

Levetiracetam requires careful monitoring in specific patient populations and clinical situations.

  • Renal impairment: dose adjustment may be necessary based on clearance.
  • Hepatic impairment: monitor liver function tests during therapy.
  • Pregnancy: risk unknown; use only if potential benefit justifies the risk.
  • Concomitant CNS depressants: observe for additive sedation.
  • Monitor for behavioral changes: report agitation, aggression, or mood swings.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Levetiracetam can interact with several medications, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine: may reduce levetiracetam plasma concentrations.
  • Phenytoin: can decrease levetiracetam effectiveness.
  • Phenobarbital: may lower levetiracetam levels.

Moderate Interactions (Monitor Closely)

  • Alcohol: potential increase in central nervous system depression.
  • Other antiepileptics: may require dose adjustments.
  • Renal excretion inhibitors: monitor for accumulation and toxicity.

Frequently Asked Questions

Levetiracetam Hospira is an intravenous antiepileptic medication used to treat epilepsy and various seizure disorders, especially when rapid seizure control is needed or oral administration is not possible.

Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal membranes, which reduces neuronal excitability and helps prevent seizure propagation.

The appropriate dose of Levetiracetam Hospira is determined by the prescribing clinician based on the patient’s condition, age, renal function, and response to therapy. No standard dosing is provided here.

Safety data for Levetiracetam Hospira in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under medical supervision.

To order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Levetiracetam has a unique mechanism targeting SV2A and generally shows fewer drug‑enzyme interactions than many older antiepileptics. It is often preferred for its broad spectrum of activity and relatively favorable side‑effect profile, though individual response varies.

Levetiracetam Hospira should be stored at 2‑8 °C, kept refrigerated, protected from light, and must not be frozen or shaken. Follow the label instructions for proper handling to maintain product integrity.

Levetiracetam Hospira is given as an intravenous infusion by a healthcare professional. The infusion rate and duration are set by the prescriber according to the patient’s clinical needs.

Serious risks include severe allergic reactions, Stevens‑Johnson syndrome, suicidal thoughts or behavior, and rare blood disorders such as neutropenia. Patients should be monitored closely for any of these signs.

Patients with known hypersensitivity to levetiracetam or any component of the formulation should avoid its use. Caution is also advised for individuals with severe renal impairment unless dose adjustments are made.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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