Product image of Levetiracetam Intrapharm Laboratories (Levetiracetam) supplied by GNH India

Levetiracetam Intrapharm Laboratories

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Intrapharm Laboratories (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Intrapharm Laboratories, is an anticonvulsant presented as an intravenous solution for injection use. It is employed in the management of partial‑onset, generalized tonic‑clonic and myoclonic seizures in patients requiring parenteral therapy.

GNH India supplies Levetiracetam Intrapharm Laboratories as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and procurement teams worldwide, with consistent quality and regulatory compliance.

Manufacturer / TM Owner

Esteve Pharmaceuticals Ltd

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Indications & Clinical Uses

Levetiracetam is an antiepileptic medication used to control seizure activity in various epilepsy syndromes.

  • Partial‑onset seizures: reduces the frequency and severity of focal seizures.
  • Generalized tonic‑clonic seizures: helps prevent convulsive episodes across both hemispheres.
  • Myoclonic seizures: decreases the occurrence of sudden, brief muscle jerks.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal membranes. This interaction reduces excessive neuronal firing and diminishes the propagation of epileptic discharges, thereby lowering seizure susceptibility.

Side Effects

Levetiracetam may cause a range of adverse reactions, some of which are more frequently observed while others are rare but serious.

Common Side Effects

  • Dizziness: mild vertigo or light‑headedness.
  • Fatigue: feeling unusually tired.
  • Headache: mild to moderate pain.
  • Nausea: upset stomach.
  • Irritability: increased agitation or mood swings.
  • Insomnia: difficulty falling or staying asleep.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or breathing difficulty.
  • Mood changes: depression, anxiety, or suicidal thoughts.
  • Blood disorders: thrombocytopenia, neutropenia, or anemia.
  • Multiorgan failure: extremely rare systemic involvement.
  • Stevens‑Johnson syndrome: severe skin reaction.
  • Hepatic dysfunction: elevated liver enzymes or hepatitis.

Precautions & Warnings

Before initiating therapy, clinicians should consider patient‑specific factors and monitor for potential complications.

  • Renal impairment: adjust therapy as needed.
  • Hepatic dysfunction: monitor liver function tests.
  • Concomitant CNS depressants: may increase sedation.
  • Pregnancy: risk unknown, use only if benefit outweighs risk.
  • Elderly: start low, monitor for confusion.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Levetiracetam can interact with other medicines, altering its effectiveness or increasing adverse effects.

Major Interactions (Avoid)

  • Carbamazepine: may reduce levetiracetam plasma levels.
  • Phenobarbital: may decrease levetiracetam efficacy.
  • Phenytoin: may lower levetiracetam concentrations.

Moderate Interactions (Monitor Closely)

  • CNS depressants (e.g., benzodiazepines): increased sedation risk.
  • Alcohol: may enhance dizziness and drowsiness.
  • Antihypertensives: possible additive hypotensive effect.

Frequently Asked Questions

Levetiracetam Intrapharm is an intravenous antiepileptic used to treat partial‑onset, generalized tonic‑clonic and myoclonic seizures in patients who require parenteral therapy. It helps control seizure frequency and severity across these seizure types.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. By stabilizing synaptic transmission, it reduces excessive neuronal excitability and limits the spread of epileptic activity, thereby decreasing seizure occurrence.

The dosing regimen for Levetiracetam Intrapharm is determined by the prescribing clinician based on the patient’s age, weight, renal function, and seizure type. Healthcare professionals set the appropriate dose and infusion rate according to current clinical guidelines.

Safety data for levetiracetam in pregnancy and lactation are limited. The medication should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and decisions should be made in consultation with a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and any required import documentation.

Levetiracetam offers a distinct mechanism by targeting SV2A, which differs from sodium‑channel blockers like carbamazepine or GABA‑enhancers such as valproate. It generally has fewer drug‑enzyme interactions, a favorable tolerability profile, and can be administered intravenously, making it useful when oral therapy is not feasible.

Levetiracetam Intrapharm should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight, and extreme temperature fluctuations to maintain stability and potency.

The product is given as an intravenous infusion. Healthcare professionals dilute the solution according to the manufacturer’s instructions and administer it over the prescribed period, typically via a peripheral or central line, while monitoring the patient for any adverse reactions.

Serious risks include severe allergic reactions (e.g., rash, angioedema, anaphylaxis), mood disturbances such as depression or suicidal thoughts, and rare blood dyscrasias like thrombocytopenia. Patients should be monitored closely for any signs of these events, and treatment should be discontinued if they occur.

Levetiracetam is contraindicated in individuals with known hypersensitivity to levetiracetam or any of its excipients. Caution is advised for patients with severe renal impairment, uncontrolled psychiatric conditions, or those taking interacting medications that could markedly reduce its effectiveness.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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