Product image of Levetiracetam Jubilant (Levetiracetam) supplied by GNH India

Levetiracetam Jubilant

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Jubilant (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Jubilant, is an anticonvulsant presented as an oral tablet for oral use. It is prescribed to manage various seizure types in patients with epilepsy, including partial, generalized tonic‑clonic, and myoclonic seizures.

GNH India supplies Levetiracetam Jubilant as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to European Union quality standards and provides reliable sourcing for bulk and unit‑dose requirements across global markets. Customers benefit from consistent product integrity, regulatory documentation, and responsive technical support.

Manufacturer / TM Owner

Jubilant Pharmaceuticals Nv

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Indications & Clinical Uses

Levetiracetam is an antiepileptic drug that reduces neuronal excitability and is indicated for several seizure types.

  • Partial seizures: helps control focal onset seizures, reducing frequency and severity.
  • Generalized tonic-clonic seizures: provides seizure control in patients with bilateral convulsive episodes.
  • Myoclonic seizures: diminishes rapid, brief muscle jerks associated with myoclonic epilepsy.

How It Works

  • Levetiracetam binds selectively to the synaptic vesicle protein SV2A, a key regulator of neurotransmitter release. This interaction modulates calcium‑dependent exocytosis, stabilizing synaptic transmission and decreasing neuronal hyper‑excitability. By limiting the release of excitatory neurotransmitters, the drug helps prevent the initiation and spread of epileptic discharges without directly affecting ion channels or G‑protein pathways.

Side Effects

Levetiracetam may be associated with a range of adverse reactions, which vary in frequency and severity.

Common Side Effects

  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Somnolence: increased sleepiness or fatigue.
  • Headache: mild to moderate cranial pain.
  • Irritability: mood changes or agitation.
  • Nausea: upset stomach, sometimes with vomiting.
  • Nasal congestion: mild upper‑respiratory discomfort.

Serious or Rare Side Effects

  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Psychiatric disturbances: depression, suicidal thoughts, or aggressive behavior.
  • Hematologic abnormalities: thrombocytopenia or leukopenia.
  • Hepatic dysfunction: elevated liver enzymes or hepatitis.
  • Allergic reactions: anaphylaxis or angioedema.

Precautions & Warnings

When prescribing Levetiracetam, clinicians should consider several precautionary measures to ensure safe use.

  • Renal impairment: adjust dose in patients with reduced kidney function.
  • History of psychiatric illness: monitor for mood changes or suicidal ideation.
  • Concomitant CNS depressants: use caution as additive sedation may occur.
  • Pregnancy: risk unknown; weigh benefits against potential fetal exposure.
  • Elderly patients: start at lower dose and titrate slowly due to altered pharmacokinetics.
  • Store at ambient temperature: keep below 25 °C, in original container, protected from moisture and light.

Avoid Interactions

Levetiracetam can interact with other medicines, influencing its effectiveness or safety profile.

Major Interactions (Avoid)

  • Carbamazepine: may reduce levetiracetam plasma levels, decreasing seizure control.
  • Phenobarbital: can lower levetiracetam concentrations, potentially compromising efficacy.

Moderate Interactions (Monitor Closely)

  • Valproic acid: may increase levetiracetam levels, requiring dose adjustment.
  • Other antiepileptic drugs (e.g., phenytoin, lamotrigine): monitor for additive CNS effects.
  • Oral contraceptives: levetiracetam may slightly reduce hormonal efficacy; consider alternative contraception.
  • Alcohol: combined use can enhance sedation and dizziness.

Frequently Asked Questions

Levetiracetam Jubilant is an antiepileptic medication indicated for the treatment of partial (focal) seizures, generalized tonic‑clonic seizures, and myoclonic seizures in patients diagnosed with epilepsy. It helps reduce the frequency and severity of seizure episodes by stabilizing neuronal activity.

Levetiracetam exerts its effect by binding to the synaptic vesicle protein SV2A, which plays a crucial role in the regulation of neurotransmitter release. This binding modulates calcium‑dependent exocytosis, leading to reduced excitatory neurotransmission and decreased neuronal hyper‑excitability that underlies seizure activity.

The dosage of Levetiracetam Jubilant is individualized and determined by the prescribing healthcare professional based on the patient’s age, weight, renal function, seizure type, and response to therapy. No fixed regimen is provided here; the prescriber will set the appropriate dose and titration schedule.

The safety of levetiracetam during pregnancy and lactation has not been definitively established. Clinicians must weigh the potential benefits for seizure control against any possible risks to the fetus or infant. If treatment is necessary, it should be continued under close medical supervision, and alternative options may be considered.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Levetiracetam Jubilant. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Levetiracetam offers a distinct mechanism of action through SV2A binding, which differs from many traditional antiepileptics that target ion channels or G‑protein pathways. It generally has a favorable drug‑interaction profile, fewer enzyme‑inducing effects, and can be used as adjunctive therapy or monotherapy, making it a versatile option compared with agents such as carbamazepine or phenytoin.

Levetiracetam Jubilant should be stored at ambient temperature, preferably below 25 °C, in its original packaging to protect from moisture and light. Keep the product out of reach of children and avoid storing in areas with high humidity or direct sunlight to maintain product stability.

Levetiracetam Jubilant is administered orally, typically as a tablet that can be swallowed whole with water. It may be taken with or without food, according to the prescriber’s instructions. Consistent timing each day helps maintain stable plasma concentrations.

Serious adverse events, although rare, include severe skin reactions such as Stevens‑Johnson syndrome, psychiatric disturbances like depression or suicidal thoughts, and hematologic abnormalities such as thrombocytopenia. Patients should seek immediate medical attention if they notice rash, mood changes, or unexplained bruising or bleeding.

Levetiracetam Jubilant is contraindicated in individuals with known hypersensitivity to levetiracetam or any of its excipients. Caution is advised for patients with severe renal impairment, uncontrolled psychiatric disorders, or those taking medications that may significantly alter its plasma levels without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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