Product image of Levetiracetam Neogen (Levetiracetam) supplied by GNH India

Levetiracetam Neogen

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Neogen (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Neogen, is an antiepileptic presented as an intravenous solution for intravenous use. It treats partial‑onset seizures, generalized tonic‑clonic seizures, and epilepsy in patients who require seizure control.

GNH India supplies Levetiracetam Neogen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Neogen N.V.

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Indications & Clinical Uses

Levetiracetam is an antiepileptic drug that acts on neuronal excitability to reduce seizure activity.

  • Partial‑onset seizures: decreases frequency of focal seizures.
  • Generalized tonic‑clonic seizures: helps control convulsive episodes.
  • Epilepsy (overall): provides adjunctive therapy for patients with refractory epilepsy.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and reducing neuronal hyper‑excitability. This interaction stabilises synaptic transmission and diminishes the propagation of epileptic discharges without directly affecting ion channels or GABA receptors.

Side Effects

Levetiracetam may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Dizziness
  • Somnolence
  • Fatigue
  • Headache
  • Nausea
  • Irritability

Serious or Rare Side Effects

  • Stevens‑Johnson syndrome or severe skin reactions
  • Suicidal ideation or severe depression
  • Blood dyscrasias such as neutropenia
  • Anaphylactic reactions
  • Severe mood changes
  • Multi‑organ hypersensitivity

Precautions & Warnings

When prescribing Levetiracetam, clinicians should consider several safety aspects.

  • Renal impairment: adjust dosing based on renal function.
  • Hepatic impairment: monitor liver enzymes and clinical response.
  • Concomitant CNS depressants: may increase sedation.
  • Pregnancy: risk unknown; discuss benefits and risks with the patient.
  • Driving or operating machinery: caution due to possible dizziness or drowsiness.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct light.

Avoid Interactions

Levetiracetam can interact with other medicines, influencing its effectiveness or safety.

Major Interactions (Avoid)

  • Carbamazepine: enzyme induction reduces levetiracetam levels.
  • Phenytoin: increases metabolism, lowering therapeutic effect.
  • Rifampin: strong inducer that may decrease plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Valproic acid: may raise levetiracetam concentrations.
  • CNS depressants (e.g., benzodiazepines): enhanced sedation risk.
  • Alcohol: additive CNS depressive effects.

Frequently Asked Questions

Levetiracetam Neogen is used as an antiepileptic medication to control partial‑onset seizures, generalized tonic‑clonic seizures, and other seizure types in patients with epilepsy. It is administered intravenously in hospital or clinical settings where rapid seizure management is required.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This action reduces neuronal hyper‑excitability and helps prevent the spread of epileptic activity without directly influencing ion channels or GABA receptors.

The dosage of Levetiracetam Neogen is determined by the prescribing clinician based on the patient’s age, weight, renal function, and seizure type. Only a qualified healthcare professional should set the appropriate dose and infusion rate.

Safety data for levetiracetam in pregnancy and lactation are limited. The prescriber should evaluate the potential benefits against possible risks and discuss these considerations with the patient before initiating therapy.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Levetiracetam has a distinct mechanism (SV2A binding) and a relatively favorable interaction profile compared with enzyme‑inducing agents like carbamazepine. It is often chosen for patients who need rapid intravenous control and for those who may experience fewer drug‑drug interactions.

Store the product at ambient temperature, below 25 °C, in its original container. Protect it from moisture and direct sunlight. Do not freeze the solution, and ensure the vial is kept upright to avoid contamination.

Levetiracetam Neogen is given by intravenous infusion. The exact infusion rate and duration are set by the treating physician, who will follow institutional protocols and monitor the patient for efficacy and tolerability.

Serious risks include severe skin reactions such as Stevens‑Johnson syndrome, suicidal thoughts or severe depression, blood dyscrasias, and anaphylactic reactions. Patients should be monitored closely for any signs of these conditions, and treatment should be stopped if they occur.

Patients with known hypersensitivity to levetiracetam or any component of the formulation should avoid its use. Caution is also advised for individuals with severe renal impairment unless dose adjustments are made, and for those with a history of serious psychiatric disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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