Product image of Levetiracetam Neuraxpharm (Levetiracetam) supplied by GNH India

Levetiracetam Neuraxpharm

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Neuraxpharm (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Neuraxpharm, is an anticonvulsant presented as an oral tablet for oral use. It treats partial‑onset, myoclonic and primary generalized tonic‑clonic seizures in patients with epilepsy.

GNH India supplies Levetiracetam Neuraxpharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Neuraxpharm Italy Spa

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Indications & Clinical Uses

Levetiracetam is an anticonvulsant that reduces abnormal neuronal firing in various seizure types.

  • Partial‑onset seizures: helps achieve seizure control in focal epilepsy.
  • Myoclonic seizures: reduces frequency and severity of sudden muscle jerks.
  • Primary generalized tonic‑clonic seizures: lowers the occurrence of convulsive episodes across the brain.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal membranes. This action reduces excessive neuronal excitability, thereby decreasing the likelihood of seizure generation without directly affecting ion channels or GABA receptors.

Side Effects

Levetiracetam may cause a range of adverse reactions.

Common Side Effects

  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Fatigue: persistent tiredness or lack of energy.
  • Somnolence: increased sleepiness during the day.
  • Headache: mild to moderate cranial pain.
  • Irritability: mood changes or increased agitation.
  • Nausea: feeling of stomach upset.

Serious or Rare Side Effects

  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Stevens‑Johnson syndrome: serious skin blistering.
  • Blood dyscrasias: abnormal blood cell counts.
  • Suicidal thoughts: new or worsening depression.
  • Severe skin rash: including toxic epidermal necrolysis.
  • Hepatic failure: signs of liver dysfunction.

Precautions & Warnings

Before prescribing Levetiracetam, consider the following safety measures.

  • Renal impairment: adjust dose based on kidney function.
  • Hepatic impairment: monitor liver enzymes regularly.
  • Pregnancy: risk unknown; weigh benefits against potential risks.
  • Concomitant CNS depressants: may enhance sedation.
  • Psychiatric disorders: monitor for mood changes or depression.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Levetiracetam can interact with several medicines; monitoring is essential.

Major Interactions (Avoid)

  • Carbamazepine: enzyme induction may lower levetiracetam levels.
  • Phenytoin: reduces efficacy of levetiracetam.
  • Phenobarbital: may decrease seizure control.
  • Rifampin: strong inducer that lowers drug concentration.
  • St. John's wort: herbal inducer that reduces exposure.

Moderate Interactions (Monitor Closely)

  • Valproic acid: may increase levetiracetam plasma levels.
  • Topiramate: combined CNS effects may increase dizziness.
  • Zonisamide: additive seizure‑control effects require observation.
  • Alcohol: enhances sedative properties.
  • Sedative hypnotics: may cause excessive drowsiness.

Frequently Asked Questions

Levetiracetam Neuraxpharm is an oral anticonvulsant indicated for the treatment of partial‑onset seizures, myoclonic seizures, and primary generalized tonic‑clonic seizures in patients diagnosed with epilepsy.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This stabilizes neuronal firing and reduces excessive excitability, helping to prevent the initiation and spread of seizure activity.

The appropriate dose is individualized and determined by the prescribing clinician based on the patient’s age, weight, renal function, seizure type, and response to therapy. No fixed regimen is provided here.

Safety data for levetiracetam in pregnancy and lactation are limited, and the pregnancy category is listed as unknown. Clinicians should assess the potential benefits against possible risks before prescribing to pregnant or nursing women.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levetiracetam offers a favorable safety profile and minimal drug‑enzyme interactions compared with many older agents such as carbamazepine or phenytoin. It is often chosen for patients who require a medication with fewer hepatic metabolism concerns, though individual response varies.

Store the tablets at ambient temperature, below 25 °C, in the original container. Protect them from moisture, excessive heat and direct sunlight to maintain potency throughout the shelf life.

Levetiracetam Neuraxpharm is taken orally, usually as a whole tablet swallowed with water. It can be taken with or without food, and dosing times should follow the prescriber’s instructions for consistent blood levels.

Serious adverse events include severe allergic reactions (e.g., anaphylaxis or Stevens‑Johnson syndrome), mood changes such as depression or suicidal thoughts, and rare blood disorders. Patients should seek immediate medical attention if these occur.

Individuals with known hypersensitivity to levetiracetam or any tablet excipients should avoid it. Caution is also advised for patients with severe renal impairment, as dose adjustments may be required, and for those with uncontrolled psychiatric conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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