Product image of Levetiracetam Puren (Levetiracetam) supplied by GNH India

Levetiracetam Puren

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Puren (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Puren, is a Anticonvulsant presented as an oral tablet for Oral use. It is used to control partial, generalized tonic‑clonic and myoclonic seizures in patients with epilepsy.
GNH India supplies Levetiracetam Puren as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Puren Pharma Gmbh & Co. Kg

1
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Indications & Clinical Uses

Levetiracetam is an antiepileptic drug that reduces abnormal neuronal firing in the brain.

  • Partial seizures: helps achieve seizure freedom or significant reduction in seizure frequency.
  • Generalized tonic‑clonic seizures: contributes to control of convulsive episodes across the patient population.
  • Myoclonic seizures: diminishes rapid muscle jerks and improves daily functioning.

How It Works

  • Levetiracetam binds selectively to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal membranes. This interaction reduces excessive neuronal excitability, thereby decreasing the likelihood of seizure initiation and propagation throughout the central nervous system.

Side Effects

Levetiracetam may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Fatigue: persistent feeling of tiredness.
  • Headache: mild to moderate cranial pain.
  • Irritability: increased emotional sensitivity.
  • Nausea: upset stomach or urge to vomit.
  • Nasal congestion: blocked or runny nose.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Mood changes: depression, anxiety, or suicidal thoughts.
  • Blood disorders: low white blood cells or platelets.
  • Liver enzyme elevation: abnormal liver function tests.
  • Skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Renal function: adjust dose in patients with impaired kidney function.
  • Psychiatric history: monitor for mood alterations or suicidal ideation.
  • Concomitant CNS depressants: assess additive sedation risk.
  • Pregnancy: discuss potential risks as safety data are limited.
  • Lactation: evaluate infant exposure through breast milk.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Levetiracetam can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine: may reduce levetiracetam plasma levels.
  • Phenobarbital: can lower levetiracetam exposure.

Moderate Interactions (Monitor Closely)

  • Alcohol: may increase central nervous system depression.
  • Other antiepileptics (e.g., valproate, phenytoin): monitor seizure control and side‑effect profile.
  • Oral contraceptives: potential reduction in hormonal efficacy; consider alternative contraception.

Frequently Asked Questions

Levetiracetam Puren is prescribed for the management of partial seizures, generalized tonic‑clonic seizures, and myoclonic seizures in patients diagnosed with epilepsy. It helps reduce the frequency and severity of seizure episodes across these seizure types.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This action stabilizes neuronal membranes and decreases excessive neuronal excitability, thereby lowering the likelihood of seizure initiation and spread within the central nervous system.

The appropriate dose of Levetiracetam Puren is determined by the prescribing healthcare professional based on the patient’s age, renal function, seizure type, and response to therapy. Dosage adjustments are individualized and should follow the prescriber’s instructions.

Safety data for levetiracetam in pregnancy are limited, and the drug is classified as having an unknown pregnancy category. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Levetiracetam Puren.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Levetiracetam offers a favorable safety profile and minimal drug‑enzyme interactions compared with many older antiepileptics such as carbamazepine or phenytoin. It is often chosen for its broad spectrum of activity across seizure types and its ease of dosing, though individual response varies.

Levetiracetam Puren should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, and avoid exposure to direct sunlight to maintain stability.

Levetiracetam Puren is taken orally, usually with or without food, as directed by the prescriber. The tablets should be swallowed whole with water and not chewed or crushed unless specifically advised.

Serious risks include severe allergic reactions (e.g., rash, swelling, breathing difficulty), mood changes such as depression or suicidal thoughts, and rare blood disorders. Patients should seek immediate medical attention if they experience any of these symptoms.

Levetiracetam Puren is contraindicated in individuals with known hypersensitivity to levetiracetam or any of its excipients. Caution is also advised for patients with severe renal impairment, uncontrolled psychiatric conditions, or those taking interacting medications without proper monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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