Product image of Levetiracetam Sandoz (Levetiracetam) supplied by GNH India

Levetiracetam Sandoz

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Sandoz (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Sandoz, is an Anticonvulsant presented as a tablet for Oral use. It treats partial‑onset seizures and generalized tonic‑clonic seizures in patients with epilepsy.

GNH India supplies Levetiracetam Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sandoz B.V.

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Indications & Clinical Uses

Levetiracetam is an anticonvulsant indicated for seizure disorders.

  • Partial‑onset seizures: reduces seizure frequency in focal epilepsy.
  • Generalized tonic‑clonic seizures: helps control convulsive seizures in generalized epilepsy.
  • Adjunct therapy for epilepsy: used with other antiepileptic drugs to improve overall seizure control.

How It Works

  • Levetiracetam binds selectively to the synaptic vesicle protein SV2A, modulating neurotransmitter release. This interaction stabilizes neuronal membranes, diminishes excessive neuronal firing, and reduces hyperexcitability in the central nervous system, thereby preventing the initiation and spread of epileptic seizures.

Side Effects

Levetiracetam may cause a range of adverse reactions.

Common Side Effects

  • Dizziness: transient sensation of light‑headedness.
  • Somnolence: increased sleepiness or fatigue.
  • Headache: mild to moderate cranial pain.
  • Irritability: mood changes or agitation.
  • Nausea: mild gastrointestinal upset.
  • Fatigue: reduced energy levels.

Serious or Rare Side Effects

  • Severe allergic reactions: rash, Stevens‑Johnson syndrome, or anaphylaxis.
  • Suicidal thoughts or behavior: emergence of depressive symptoms.
  • Severe depression or mood disorders: may require immediate medical attention.
  • Blood dyscrasias: rare cases of leukopenia or thrombocytopenia.
  • Multi‑organ hypersensitivity: systemic reactions involving liver or kidneys.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Renal impairment: dose may need adjustment based on kidney function.
  • Hepatic dysfunction: monitor liver enzymes during treatment.
  • Pregnancy: risk category unknown; discuss potential benefits and risks with a healthcare professional.
  • Psychiatric symptoms: observe for mood changes, depression, or suicidal ideation.
  • Concomitant CNS depressants: may enhance sedation or dizziness.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Levetiracetam can interact with several medications; awareness helps maintain efficacy and safety.

Major Interactions (Avoid)

  • Carbamazepine: may lower levetiracetam plasma concentrations.
  • Phenobarbital: can reduce levetiracetam effectiveness.
  • Phenytoin: may decrease levetiracetam levels.

Moderate Interactions (Monitor Closely)

  • Alcohol: may increase central nervous system depression.
  • Other antiepileptic drugs: dose adjustments may be required.
  • Renal excretion inhibitors: monitor renal function and consider dose modification.

Frequently Asked Questions

Levetiracetam Sandoz is used to treat partial‑onset seizures and generalized tonic‑clonic seizures in patients with epilepsy. It helps reduce the frequency and severity of seizure episodes by stabilizing neuronal activity in the brain.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates the release of neurotransmitters. This action reduces neuronal hyperexcitability and prevents the rapid spread of electrical activity that leads to seizures.

The appropriate dose of levetiracetam is determined individually by a prescriber based on the patient’s age, weight, renal function, and seizure type. Patients should follow the dosing instructions provided by their healthcare professional.

The safety of levetiracetam in pregnancy and lactation is not fully established. Healthcare providers weigh potential benefits against possible risks and may recommend alternative therapies or close monitoring if treatment is continued.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levetiracetam offers a distinct mechanism by targeting SV2A, which differs from sodium‑channel blockers like carbamazepine. It generally has fewer drug‑enzyme interactions, a favorable tolerability profile, and can be used as monotherapy or adjunct therapy, making it a versatile option in seizure management.

Store the tablets at ambient temperature, below 25 °C, in the original packaging. Protect them from moisture, excessive heat, and direct sunlight to maintain product stability throughout its shelf life.

Levetiracetam Sandoz is taken orally, usually with or without food, as directed by a healthcare professional. Tablets should be swallowed whole with water and not chewed or crushed unless specifically instructed.

Serious risks include severe allergic reactions such as rash or Stevens‑Johnson syndrome, emergence of suicidal thoughts or behavior, and rare blood disorders. Patients should seek immediate medical attention if they notice any of these symptoms.

Levetiracetam is contraindicated in individuals with known hypersensitivity to the drug or any of its excipients. Caution is also advised for patients with severe renal impairment, as dose adjustments may be required.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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