Product image of Levetiracetam Sciecure (Levetiracetam) supplied by GNH India

Levetiracetam Sciecure

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Sciecure (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Sciecure, is an anticonvulsant presented as an intravenous solution for intravenous use. It treats partial‑onset, generalized tonic‑clonic and myoclonic seizures in patients who require parenteral therapy.

GNH India supplies Levetiracetam Sciecure as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Genmed Pharma Gmbh

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Indications & Clinical Uses

  • Levetiracetam is used in the management of epilepsy, targeting neuronal hyperexcitability.
  • Partial‑onset seizures: reduces the frequency of focal seizure episodes.
  • Generalized tonic‑clonic seizures: helps control convulsive episodes in generalized epilepsy.
  • Myoclonic seizures: decreases the occurrence of rapid muscle jerks in appropriate seizure types.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating its activity and thereby decreasing the release of excitatory neurotransmitters. This action stabilises neuronal firing and reduces hyper‑excitability in the central nervous system, contributing to seizure control.

Side Effects

Levetiracetam may be associated with a range of adverse reactions that vary in frequency and severity.

Common Side Effects

  • Dizziness
  • Somnolence
  • Fatigue
  • Headache
  • Irritability
  • Nausea

Serious or Rare Side Effects

  • Severe allergic reactions (e.g., anaphylaxis, angioedema)
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Blood dyscrasias such as neutropenia or thrombocytopenia
  • Suicidal thoughts or severe depression
  • Hepatic failure (very rare)

Precautions & Warnings

  • When using Levetiracetam Sciecure, consider the following safety measures.
  • Renal impairment: adjust dose based on creatinine clearance.
  • Behavioral changes: monitor patients for agitation, aggression or mood swings.
  • Hypersensitivity: discontinue if a rash or other allergic signs develop.
  • Pregnancy: use only if the potential benefit justifies the potential risk, as safety data are limited.
  • Severe skin reaction: stop treatment immediately if signs of Stevens‑Johnson syndrome appear.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

Avoid Interactions

Levetiracetam can interact with other medicines; awareness of the interaction level guides clinical decisions.

Major Interactions (Avoid)

  • Co‑administration with strong enzyme inducers such as phenobarbital, phenytoin or carbamazepine may reduce levetiracetam plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Concurrent use with other central nervous system depressants (e.g., benzodiazepines) may increase sedation.
  • Combined with oral contraceptives, levetiracetam may lower contraceptive efficacy; additional barrier methods are advised.
  • Use with nephrotoxic agents may heighten the risk of renal impairment; monitor renal function regularly.

Frequently Asked Questions

Levetiracetam Sciecure is an intravenous antiepileptic medication indicated for the treatment of partial‑onset, generalized tonic‑clonic and myoclonic seizures in patients who need parenteral therapy.

Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and reducing neuronal excitability. This stabilises abnormal electrical activity in the brain, helping to prevent seizure propagation.

The appropriate dose is determined by the prescribing clinician based on the patient’s age, weight, renal function and seizure type. Dosage regimens are individualized and should follow the prescriber’s instructions.

Safety data for Levetiracetam in pregnancy are limited, and the product is classified as having an unknown pregnancy category. It should be used only if the potential benefit outweighs the risk. Breastfeeding decisions should be made in consultation with a healthcare professional.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and necessary import documentation.

Levetiracetam has a distinct mechanism (SV2A modulation) and a relatively low potential for drug‑drug interactions compared with many enzyme‑inducing antiepileptics such as carbamazepine or phenytoin. It is often chosen for its rapid onset when given intravenously and its favourable tolerability profile.

The product should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the vial in its original packaging until use to maintain stability.

Levetiracetam Sciecure is administered by intravenous infusion under the supervision of a qualified healthcare professional. The infusion rate and duration are set by the prescriber according to the patient’s clinical condition.

Serious risks include severe allergic reactions such as anaphylaxis, life‑threatening skin conditions like Stevens‑Johnson syndrome, blood dyscrasias, and the emergence of suicidal thoughts or severe depression. Immediate medical attention is required if any of these occur.

Patients with known hypersensitivity to levetiracetam or any component of the formulation should avoid its use. Caution is also advised in individuals with severe renal impairment, uncontrolled psychiatric conditions, or those who have experienced serious skin reactions to antiepileptic drugs.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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