Product image of Levetiracetam Stada (Levetiracetam) supplied by GNH India

Levetiracetam Stada

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Stada (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Stada, is an anticonvulsant presented as an oral tablet for oral use. It treats partial‑onset, generalized tonic‑clonic, and myoclonic seizures in patients with epilepsy.

GNH India supplies Levetiracetam Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stadapharm Gmbh

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Indications & Clinical Uses

  • Levetiracetam is an antiepileptic drug used to control various seizure types.
  • Partial‑onset seizures: reduces seizure frequency in focal epilepsy.
  • Generalized tonic‑clonic seizures: helps prevent convulsive episodes.
  • Myoclonic seizures: decreases rapid, involuntary muscle jerks associated with juvenile myoclonic epilepsy.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal firing. This action reduces abnormal neuronal excitability without significant interaction with ion channels or G‑protein pathways, contributing to its broad antiepileptic effect across multiple seizure types.

Side Effects

Levetiracetam may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Dizziness
  • Fatigue
  • Somnolence
  • Irritability or mood changes
  • Headache
  • Nausea or gastrointestinal discomfort

Serious or Rare Side Effects

  • Severe allergic reactions (e.g., anaphylaxis, angioedema)
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Suicidal thoughts or behavior
  • Severe skin rash or hypersensitivity
  • Blood dyscrasias such as neutropenia or thrombocytopenia
  • Multi‑organ involvement or hepatic injury

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Renal impairment: adjust dose based on creatinine clearance.
  • Pregnancy: risk category unknown; discuss potential benefits and risks with a healthcare professional.
  • Psychiatric symptoms: monitor for mood swings, depression, or aggression.
  • Concomitant CNS depressants: may increase sedation or dizziness.
  • Hepatic dysfunction: use with caution and monitor liver function.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Levetiracetam has a relatively low interaction profile, but certain combinations require attention.

Major Interactions (Avoid)

  • Enzyme‑inducing antiepileptics (e.g., carbamazepine, phenytoin, phenobarbital): may lower levetiracetam plasma concentrations.
  • Strong CYP inducers: can reduce efficacy and require dose adjustment.

Moderate Interactions (Monitor Closely)

  • Alcohol: may enhance central nervous system depression.
  • Sedative hypnotics or opioids: increase risk of excessive sedation.
  • Other antiepileptics (e.g., valproate): may heighten adverse‑effect profile.
  • Renally cleared drugs: monitor renal function to avoid accumulation.

Frequently Asked Questions

Levetiracetam Stada is prescribed for the management of partial‑onset seizures, generalized tonic‑clonic seizures, and myoclonic seizures in patients diagnosed with epilepsy. It helps reduce the frequency and severity of these seizure types by stabilizing neuronal activity.

Levetiracetam binds to the synaptic vesicle protein SV2A, which plays a key role in neurotransmitter release. This binding modulates vesicle exocytosis, leading to decreased neuronal hyper‑excitability and a lower likelihood of seizure propagation.

The dose of Levetiracetam Stada is individualized by the prescribing clinician based on the patient’s age, renal function, seizure type, and response to therapy. Dosage adjustments are made to achieve optimal seizure control while minimizing adverse effects.

Levetiracetam is classified as a pregnancy category with limited data; its safety is not fully established. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the medication.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Compared with many traditional antiepileptics, levetiracetam has a relatively simple pharmacokinetic profile, few drug‑enzyme interactions, and does not require routine therapeutic drug monitoring. Its efficacy across multiple seizure types makes it a common alternative to drugs such as carbamazepine or valproate, especially when drug‑interaction risk is a concern.

Levetiracetam Stada should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, excessive heat, and direct sunlight to maintain stability and potency.

Levetiracetam Stada is administered orally, typically as a tablet swallowed with water. The exact dosing schedule—once daily, twice daily, or more—depends on the prescriber’s assessment of the patient’s seizure pattern and renal function.

Serious risks include severe allergic reactions such as anaphylaxis, skin conditions like Stevens‑Johnson syndrome, and neuropsychiatric events including suicidal thoughts or aggressive behavior. Patients should seek immediate medical attention if they experience rash, swelling, mood changes, or any signs of an allergic reaction.

Levetiracetam Stada is contraindicated in individuals with known hypersensitivity to levetiracetam or any of its excipients. Caution is also advised for patients with severe renal impairment who cannot be appropriately dose‑adjusted, and for those with a history of serious psychiatric disorders unless closely monitored.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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