Product image of Levetiracetam Stada (Levetiracetam) supplied by GNH India

Levetiracetam Stada

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Stada (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Stada, is a Antiepileptic presented as an oral tablet for Oral use. It treats partial, generalized tonic‑clonic and myoclonic seizures in patients with epilepsy.

GNH India supplies Levetiracetam Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Ag

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Indications & Clinical Uses

Levetiracetam is an antiepileptic drug that modulates neuronal excitability to control seizure activity.

  • Partial seizures: reduces seizure frequency in patients with focal epilepsy.
  • Generalized tonic‑clonic seizures: helps achieve seizure control in primary generalized epilepsy.
  • Myoclonic seizures: diminishes myoclonic jerks in appropriate seizure syndromes.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, a key regulator of neurotransmitter release. This interaction modulates synaptic vesicle exocytosis, decreasing neuronal hyper‑excitability and thereby reducing the likelihood of seizure propagation across neuronal networks.

Side Effects

Levetiracetam may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Dizziness: transient sensation of light‑headedness.
  • Fatigue: feeling unusually tired or low in energy.
  • Somnolence: increased sleepiness during the day.
  • Irritability: mood changes or heightened agitation.
  • Headache: mild to moderate cranial pain.
  • Nausea: upset stomach or feeling of queasiness.

Serious or Rare Side Effects

  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Stevens‑Johnson syndrome: rare but life‑threatening skin disorder.
  • Suicidal thoughts: emergence of depressive ideation.
  • Blood dyscrasias: abnormal blood counts such as neutropenia.
  • Multi‑organ hypersensitivity: systemic reaction affecting liver, kidneys, or lungs.
  • Severe skin rash: extensive erythema or blistering.

Precautions & Warnings

Before initiating therapy, clinicians should assess individual risk factors and monitor patients regularly.

  • Renal impairment: adjust dose according to renal function.
  • Hepatic dysfunction: use with caution; monitor liver enzymes.
  • Psychiatric history: observe for mood changes or suicidal ideation.
  • Concomitant CNS depressants: may enhance sedation; dose adjustments may be needed.
  • Pregnancy and lactation: discuss potential risks with a healthcare professional.
  • Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Levetiracetam can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine, phenytoin, phenobarbital: enzyme‑inducing agents that may lower levetiracetam plasma levels.
  • Alcohol: can increase central nervous system depression.

Moderate Interactions (Monitor Closely)

  • Benzodiazepines or opioids: may enhance sedative effects.
  • Probenecid or other renal excretion inhibitors: may raise levetiracetam concentrations.
  • Live vaccines: potential reduction in vaccine efficacy.
  • Other antiepileptic drugs: may require dose titration based on clinical response.

Frequently Asked Questions

Levetiracetam Stada is prescribed to control seizures in patients with epilepsy. It is indicated for partial (focal) seizures, generalized tonic‑clonic seizures, and myoclonic seizures, helping to reduce the frequency and severity of seizure episodes when used as part of an individualized treatment plan.

Levetiracetam binds to the synaptic vesicle protein SV2A, which plays a crucial role in neurotransmitter release. By modulating SV2A activity, the drug stabilises neuronal firing and diminishes excessive excitability, thereby lowering the risk of seizure initiation and spread across the brain.

The specific dose of Levetiracetam Stada is determined by the prescribing clinician based on the patient’s age, weight, renal function, seizure type, and response to therapy. Healthcare professionals tailor the regimen to achieve optimal seizure control while minimising side effects.

Safety data for levetiracetam in pregnancy and lactation are limited. The drug should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss treatment options with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.

Levetiracetam offers a favourable safety profile and minimal drug‑enzyme interactions compared with many older antiepileptics such as carbamazepine or phenytoin. It is often preferred when clinicians seek a medication with fewer hepatic metabolism concerns, though individual response and tolerability ultimately guide drug selection.

Levetiracetam Stada should be stored at ambient temperature below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.

Levetiracetam Stada is taken orally, usually as a whole tablet swallowed with water. It can be taken with or without food, but patients should follow the prescribing information and maintain a consistent dosing schedule to ensure stable blood levels.

Serious adverse events, although rare, include severe allergic reactions such as Stevens‑Johnson syndrome, suicidal thoughts or behaviours, significant skin rashes, and blood dyscrasias like neutropenia. Patients should seek immediate medical attention if they notice any of these symptoms.

Levetiracetam Stada is contraindicated in individuals with known hypersensitivity to levetiracetam or any of its excipients. Caution is also advised for patients with severe renal impairment who may require dose adjustment, and for those with a history of psychiatric disorders who need close monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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