Product image of Levetiracetam Stadafarma (Levetiracetam) supplied by GNH India

Levetiracetam Stadafarma

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Stadafarma (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Stadafarma, is an anticonvulsant presented as an oral dosage form for systemic use. It is employed in the management of epilepsy, specifically targeting partial‑onset, generalized tonic‑clonic and myoclonic seizures in adult and pediatric patients.

GNH India supplies Levetiracetam Stadafarma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable access to quality‑assured antiepileptic medicines for diverse healthcare markets, with consistent batch testing, regulatory compliance and on‑time delivery to meet patient needs.

Manufacturer / TM Owner

Laboratorio Stada, S.L.

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Indications & Clinical Uses

  • Levetiracetam is an antiepileptic medication that modulates neuronal excitability in seizure disorders.
  • Partial‑onset seizures: reduces the frequency of focal seizure episodes in patients with epilepsy.
  • Generalized tonic‑clonic seizures: helps prevent convulsive seizures across the whole brain.
  • Myoclonic seizures: diminishes rapid, brief muscle jerks associated with certain epilepsy syndromes.

How It Works

  • Levetiracetam binds selectively to the synaptic vesicle protein SV2A, a key regulator of neurotransmitter release. This interaction modulates synaptic transmission, decreasing excessive neuronal firing and stabilising neuronal networks, which in turn reduces the likelihood of seizure generation and propagation.

Side Effects

Levetiracetam may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Dizziness
  • Somnolence
  • Fatigue
  • Headache
  • Irritability
  • Nausea

Serious or Rare Side Effects

  • Severe allergic reactions (e.g., anaphylaxis, angioedema)
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Blood dyscrasias such as neutropenia or thrombocytopenia
  • Suicidal thoughts or behavior
  • Severe depression or mood changes
  • Rash with systemic involvement

Precautions & Warnings

  • Before initiating therapy, consider patient‑specific factors and monitor for potential risks.
  • Renal impairment: adjust dose based on creatinine clearance.
  • History of psychiatric disorders: monitor mood changes and suicidal ideation.
  • Concomitant CNS depressants: assess for additive sedation.
  • Pregnancy and lactation: evaluate risk‑benefit ratio with a healthcare professional.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Levetiracetam may interact with other medicines, influencing its efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine: may lower levetiracetam plasma concentrations.
  • Phenobarbital: can reduce levetiracetam exposure.
  • Phenytoin: may decrease levetiracetam levels.
  • Valproic acid: potential increase in levetiracetam concentration.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: efficacy may be reduced.
  • Alcohol: may enhance central nervous system depression.

Frequently Asked Questions

Levetiracetam Stadafarma is an antiepileptic medicine indicated for the treatment of partial‑onset seizures, generalized tonic‑clonic seizures, and myoclonic seizures in patients with epilepsy. It helps to reduce the frequency and severity of seizure episodes across these seizure types.

Levetiracetam binds to the synaptic vesicle protein SV2A, which plays a crucial role in regulating neurotransmitter release. By modulating SV2A activity, the drug stabilises neuronal firing and diminishes excessive excitability, thereby lowering the likelihood of seizure initiation and spread.

The dosage of Levetiracetam Stadafarma is individualized and determined by the prescribing healthcare professional based on the patient’s age, weight, renal function, and seizure type. Patients should follow the dose prescribed by their clinician and not adjust it without medical advice.

Safety data for levetiracetam in pregnancy and lactation are limited. The medication should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss treatment options with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details (including any cold‑chain requirements) and assists with import documentation.

Levetiracetam offers a distinct mechanism of action by targeting SV2A, which differs from sodium‑channel blockers such as carbamazepine or phenytoin. It generally has fewer drug‑enzyme interactions, a favorable pharmacokinetic profile, and is often well tolerated, making it a useful alternative or adjunct in patients who experience side effects with other agents.

Store Levetiracetam Stadafarma at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight and excessive heat. Do not use if the packaging is damaged or if the tablets show signs of degradation.

Levetiracetam Stadafarma is taken orally, usually with or without food, as directed by the prescribing clinician. The tablets should be swallowed whole with water and not crushed or chewed unless specifically instructed.

Serious adverse reactions, although rare, include severe allergic responses such as anaphylaxis, Stevens‑Johnson syndrome, blood dyscrasias, and significant mood changes including suicidal thoughts or severe depression. Patients should seek immediate medical attention if they experience rash, fever, unexplained bruising, or any sudden change in mood or behavior.

Levetiracetam Stadafarma is contraindicated in individuals with known hypersensitivity to levetiracetam or any of its excipients. Caution is advised for patients with severe renal impairment, uncontrolled psychiatric disorders, or those taking medications that may significantly alter its plasma levels without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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