Product image of Levetiracetam Stadagen (Levetiracetam) supplied by GNH India

Levetiracetam Stadagen

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Stadagen (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Stadagen, is an anticonvulsant presented as an oral tablet for oral use. It is employed to control partial, generalized tonic‑clonic and myoclonic seizures in patients diagnosed with epilepsy. The medication is indicated for individuals of various ages who require seizure management as part of a comprehensive treatment plan.

GNH India supplies Levetiracetam Stadagen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for global distribution.

Manufacturer / TM Owner

Laboratorio Stada, S.L.

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Indications & Clinical Uses

Levetiracetam is an anticonvulsant indicated for several seizure disorders that affect the central nervous system.

  • Partial seizures: reduces frequency of focal onset seizures.
  • Generalized tonic‑clonic seizures: helps control convulsive episodes.
  • Myoclonic seizures: decreases occurrence of rapid muscle jerks.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, a key regulator of neurotransmitter release. This interaction modulates vesicle exocytosis, leading to reduced neuronal excitability and stabilization of synaptic transmission. By limiting excessive firing of neurons, the drug helps prevent the initiation and spread of epileptic activity without significantly affecting other ion channels or receptors.

Side Effects

Levetiracetam may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Dizziness
  • Fatigue
  • Somnolence
  • Headache
  • Nausea

Serious or Rare Side Effects

  • Severe allergic reactions (e.g., rash, Stevens‑Johnson syndrome)
  • Mood alterations such as depression or suicidal thoughts
  • Blood disorders including thrombocytopenia
  • Multi‑organ hypersensitivity reactions

Precautions & Warnings

When prescribing levetiracetam, clinicians should consider several safety precautions.

  • Renal impairment: assess kidney function and adjust dose if necessary.
  • Hepatic impairment: monitor liver enzymes and use caution.
  • Psychiatric symptoms: observe for mood changes, depression, or aggression.
  • Concomitant CNS depressants: may increase sedation; monitor patient response.
  • Pregnancy: limited data; evaluate risk‑benefit before use.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

Avoid Interactions

Levetiracetam has a relatively low interaction profile, but certain drug combinations require attention.

Major Interactions (Avoid)

  • Strong enzyme inducers (e.g., carbamazepine, phenytoin, phenobarbital): may lower levetiracetam plasma concentrations.
  • Alcohol or other CNS depressants: can enhance sedative effects.

Moderate Interactions (Monitor Closely)

  • Renally cleared drugs (e.g., digoxin, certain antibiotics): monitor therapeutic levels.
  • Antidepressants (e.g., SSRIs, SNRIs): watch for increased risk of mood changes.
  • Immunosuppressants (e.g., tacrolimus, cyclosporine): may require concentration monitoring.

Frequently Asked Questions

Levetiracetam Stadagen is prescribed to manage epilepsy by reducing the frequency of partial, generalized tonic‑clonic, and myoclonic seizures. It is part of a broader seizure‑control regimen and is used in patients who require an oral anticonvulsant to stabilize neuronal activity.

Levetiracetam binds to the synaptic vesicle protein SV2A, which plays a crucial role in neurotransmitter release. This binding modulates vesicle exocytosis, decreasing neuronal excitability and helping to prevent the rapid, uncontrolled firing of brain cells that leads to seizures.

The appropriate dose of Levetiracetam Stadagen is individualized and set by the prescribing healthcare professional. Dosage depends on factors such as the patient’s age, weight, renal function, seizure type, and response to therapy, and should be followed as directed by the prescriber.

Data on levetiracetam use in pregnancy and lactation are limited. The medication should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant. Clinicians typically assess each case carefully and discuss alternatives when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. The sales team then provides pricing, availability, shipping details (including any cold‑chain requirements) and assists with import documentation.

Levetiracetam offers a favorable safety profile with minimal enzyme‑inducing effects, unlike many older antiepileptics such as carbamazepine or phenytoin. It is generally well tolerated, has fewer drug‑interaction concerns, and can be used as monotherapy or adjunct therapy. However, individual response varies, and the choice of medication should be based on seizure type, comorbidities and patient tolerance.

Levetiracetam Stadagen should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure the packaging remains tightly closed until use.

The medication is taken orally, usually as a tablet swallowed whole with water. It can be taken with or without food, according to the prescriber’s instructions. Consistent timing each day helps maintain stable blood levels.

Patients should be alert for severe allergic reactions such as rash, Stevens‑Johnson syndrome, or facial swelling, as well as significant mood changes including depression, anxiety, or suicidal thoughts. Unexplained bruising or bleeding may indicate blood‑disorder complications. Any of these symptoms warrant immediate medical evaluation.

Levetiracetam Stadagen is contraindicated in individuals with a known hypersensitivity to levetiracetam or any of its excipients. Caution is advised for patients with severe renal impairment, as dose adjustment may be required, and for those with a history of serious psychiatric disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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