Product image of Levetiracetam Stragen (Levetiracetam) supplied by GNH India

Levetiracetam Stragen

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Stragen (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Stragen, is an anticonvulsant presented as an intravenous solution for parenteral use. It treats partial‑onset, myoclonic and primary generalized tonic‑clonic seizures in patients requiring seizure control.

GNH India supplies Levetiracetam Stragen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and transplant centres worldwide.

Manufacturer / TM Owner

Stragen Nordic A/S

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Indications & Clinical Uses

Levetiracetam is an antiepileptic drug used to manage various seizure types.

  • Partial‑onset seizures: reduces the frequency of focal seizures in adults and children.
  • Myoclonic seizures: controls rapid, involuntary muscle jerks associated with juvenile myoclonic epilepsy.
  • Primary generalized tonic‑clonic seizures: prevents generalized convulsive episodes in patients with idiopathic generalized epilepsy.

How It Works

  • Levetiracetam binds selectively to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal firing. This interaction reduces neuronal hyperexcitability, thereby decreasing the likelihood of seizure propagation without directly affecting ion channels or GABA receptors.

Side Effects

Levetiracetam may be associated with a range of adverse reactions, most of which are mild to moderate in severity.

Common Side Effects

  • Dizziness: sensation of lightheadedness or unsteadiness.
  • Fatigue: feeling unusually tired or weak.
  • Headache: mild to moderate head pain.
  • Irritability: mood changes or increased agitation.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Mood or behavior changes: depression, suicidal thoughts, or aggression.
  • Hematologic abnormalities: low blood cell counts such as leukopenia or thrombocytopenia.

Precautions & Warnings

When prescribing Levetiracetam, clinicians should consider several precautionary measures to ensure safe use.

  • Renal impairment: adjust dose in patients with reduced kidney function.
  • History of psychiatric disorders: monitor for mood changes or suicidal ideation.
  • Concomitant CNS depressants: use caution as additive sedation may occur.
  • Pregnancy: potential risks are unknown; evaluate benefit‑risk ratio.
  • Lactation: unknown safety; consider alternatives or monitor infant.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Levetiracetam can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • None identified: no major drug interactions have been documented.

Moderate Interactions (Monitor Closely)

  • Carbamazepine, phenytoin, phenobarbital: enzyme inducers may lower levetiracetam concentrations.
  • Valproic acid: may increase levetiracetam levels modestly.
  • Sedative agents (benzodiazepines, opioids): additive CNS depression may occur.
  • Oral contraceptives: levetiracetam may reduce hormonal contraceptive efficacy.

Frequently Asked Questions

Levetiracetam Stragen is used to treat epilepsy by reducing the frequency of partial‑onset, myoclonic, and primary generalized tonic‑clonic seizures. It is administered intravenously in hospital settings where rapid seizure control is required.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This action stabilizes neuronal firing and lowers hyperexcitability, helping to prevent the spread of seizure activity without directly influencing ion channels.

The appropriate dose of Levetiracetam Stragen is determined by the prescribing clinician based on the patient’s age, weight, renal function, and seizure type. Dosage regimens are individualized and should follow the prescriber’s instructions.

Safety data for Levetiracetam during pregnancy and lactation are limited. The medication should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and decisions should be made in consultation with a healthcare professional.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and import documentation.

Levetiracetam offers a distinct mechanism (SV2A binding) and generally has fewer drug‑enzyme interactions than older agents such as carbamazepine or phenytoin. It is often preferred for patients who require rapid intravenous control or who have experienced adverse effects with other antiepileptics.

Levetiracetam Stragen should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture and direct light. Do not freeze the solution, and inspect it for particulate matter before administration.

The product is supplied as an intravenous solution and is administered by slow infusion under medical supervision. The infusion rate and total daily dose are set by the treating physician according to the patient’s clinical condition.

Serious risks include severe allergic reactions (rash, swelling, breathing difficulty), significant mood or behavioral changes such as depression or suicidal thoughts, and rare hematologic abnormalities like low white‑blood‑cell or platelet counts. Prompt medical attention is required if any of these occur.

Patients with a known hypersensitivity to levetiracetam or any component of the formulation should avoid its use. Caution is also advised for individuals with severe renal impairment, as dose adjustment may be required, and for those with a history of serious psychiatric disorders.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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