Product image of Levetiracetam Sun (Levetiracetam) supplied by GNH India

Levetiracetam Sun

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Sun (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Sun, is an anticonvulsant presented as a sterile powder for reconstitution for intravenous injection. It is used to manage partial‑onset, generalized tonic‑clonic and myoclonic seizures in patients who require rapid and reliable seizure control.

GNH India supplies Levetiracetam Sun as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution channels that meet EU regulatory standards. The company ensures product quality and traceability from manufacture to delivery through rigorous quality control and cold‑chain logistics where required.

Manufacturer / TM Owner

Sun Pharmaceutical Industries Europe B.V.

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Indications & Clinical Uses

Levetiracetam is an anticonvulsant used to treat several seizure types by modulating neuronal excitability.

  • Partial-onset seizures: reduces frequency and severity of focal seizures.
  • Generalized tonic-clonic seizures: helps control convulsive episodes in generalized epilepsy.
  • Myoclonic seizures: diminishes rapid muscle jerks associated with myoclonic epilepsy.

How It Works

  • Levetiracetam binds selectively to the synaptic vesicle protein SV2A, a key regulator of neurotransmitter release. This interaction modulates calcium‑dependent exocytosis, stabilizing synaptic transmission and decreasing neuronal hyperexcitability. By limiting excessive glutamate release, the drug helps prevent the synchronous neuronal firing that underlies seizure activity, without directly affecting ion channels or GABA receptors.

Side Effects

Levetiracetam may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Fatigue: feeling unusually tired or weak.
  • Headache: mild to moderate cranial pain.
  • Nausea: upset stomach or urge to vomit.
  • Irritability: mood changes or increased agitation.
  • Somnolence: excessive sleepiness.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Stevens‑Johnson syndrome: severe skin blistering and mucosal involvement.
  • Hematologic abnormalities: low blood cell counts such as neutropenia.
  • Mood or behavioral changes: depression, suicidal thoughts, or aggression.
  • Hepatic dysfunction: elevated liver enzymes or liver injury.

Precautions & Warnings

When prescribing Levetiracetam, clinicians should consider several precautionary measures to ensure safe use.

  • Renal impairment: adjust dose in patients with reduced kidney function.
  • History of psychiatric disorders: monitor for mood changes or aggression.
  • Concomitant CNS depressants: use caution as combined effects may increase sedation.
  • Pregnancy: avoid unless benefits outweigh potential risks, as safety data are limited.
  • Elderly patients: start at lower doses and titrate slowly due to increased sensitivity.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Levetiracetam can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine: may reduce levetiracetam plasma levels, decreasing effectiveness.
  • Phenobarbital: can lower levetiracetam concentrations, requiring close monitoring.

Moderate Interactions (Monitor Closely)

  • Valproic acid: may increase risk of adverse CNS effects.
  • Opioids: combined use may enhance sedation and respiratory depression.
  • Fluoroquinolones: potential for increased neurotoxicity.
  • Alcohol: may intensify dizziness and drowsiness.

Frequently Asked Questions

Levetiracetam Sun is an intravenous formulation of levetiracetam indicated for the treatment of partial‑onset, generalized tonic‑clonic and myoclonic seizures in patients who need rapid seizure control, typically in hospital or acute care settings.

Levetiracetam binds to the synaptic vesicle protein SV2A, modulating calcium‑dependent neurotransmitter release. This stabilizes synaptic activity and reduces neuronal hyperexcitability, thereby preventing the synchronized firing that generates seizures.

The dosage of Levetiracetam Sun is determined by the prescribing clinician based on the patient’s age, weight, renal function and seizure type. The prescriber sets the exact regimen and any necessary adjustments.

Safety data for levetiracetam during pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where applicable) and necessary import documentation.

Compared with older anticonvulsants such as valproic acid or carbamazepine, levetiracetam has a distinct mechanism (SV2A binding), fewer drug‑enzyme interactions, and a generally favorable tolerability profile, though individual response and side‑effect risk vary among patients.

Levetiracetam Sun should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. The product should be kept in its original packaging until reconstitution and administered promptly after preparation.

Levetiracetam Sun is supplied as a sterile powder for reconstitution with a suitable diluent and is administered by intravenous infusion, typically over 15 minutes to 30 minutes, under the supervision of qualified medical personnel.

Serious risks include severe allergic reactions such as Stevens‑Johnson syndrome, hematologic abnormalities like neutropenia, significant mood or behavioral changes (including depression or suicidal thoughts), and hepatic dysfunction. Immediate medical attention is required if any of these occur.

Levetiracetam Sun is contraindicated in patients with known hypersensitivity to levetiracetam or any component of the formulation. Caution is also advised for individuals with severe renal impairment, uncontrolled psychiatric conditions, or those who are pregnant unless the therapeutic benefit justifies the potential risk.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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