Product image of Levetiracetam Tarbis (Levetiracetam) supplied by GNH India

Levetiracetam Tarbis

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Tarbis (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Tarbis, is an anticonvulsant presented as a injectable solution for intravenous use. It treats partial‑onset, generalized tonic‑clonic and myoclonic seizures in patients requiring seizure control.

GNH India supplies Levetiracetam Tarbis as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Tarbis Farma, S.L.

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Indications & Clinical Uses

Levetiracetam is used to manage seizure disorders by stabilizing neuronal activity.

  • Partial‑onset seizures: reduces frequency of seizure episodes.
  • Generalized tonic‑clonic seizures: helps achieve seizure control.
  • Myoclonic seizures: decreases occurrence of myoclonic jerks.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and reducing neuronal hyperexcitability. This action stabilizes synaptic transmission without directly affecting ion channels or GABA receptors, contributing to its anticonvulsant effect across various seizure types.

Side Effects

Levetiracetam may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Dizziness: transient lightheadedness.
  • Fatigue: general tiredness.
  • Headache: mild cranial pain.
  • Nausea: upset stomach.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or anaphylaxis.
  • Mood or behavior changes: depression, suicidal thoughts, or aggression.
  • Hematologic abnormalities: low blood cell counts.
  • Stevens‑Johnson syndrome: severe skin reaction.

Precautions & Warnings

When prescribing Levetiracetam, clinicians should consider several safety precautions.

  • Renal impairment: adjust dose or monitor renal function.
  • History of psychiatric disorders: monitor mood and behavior changes.
  • Concomitant CNS depressants: observe for enhanced sedation.
  • Pregnancy: use only if benefit outweighs risk, as safety data are limited.
  • Lactation: unknown safety, weigh benefits against potential infant exposure.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Levetiracetam can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine: may reduce levetiracetam plasma levels.
  • Phenobarbital: may decrease levetiracetam exposure.
  • Phenytoin: may lower levetiracetam concentrations.

Moderate Interactions (Monitor Closely)

  • Opioids: increased risk of sedation or respiratory depression.
  • Alcohol: may enhance central nervous system depression.
  • Other antiepileptic drugs: monitor seizure control and side effects.

Frequently Asked Questions

Levetiracetam Tarbis is an injectable formulation of levetiracetam, an anticonvulsant medication indicated for the treatment of partial‑onset seizures, generalized tonic‑clonic seizures, and myoclonic seizures. It is administered intravenously in hospital or clinical settings to provide rapid seizure control in patients who require an immediate therapeutic effect or cannot take oral medications.

Levetiracetam exerts its antiepileptic effect by binding to the synaptic vesicle protein SV2A. This interaction modulates neurotransmitter release, stabilizing synaptic transmission and reducing neuronal hyper‑excitability. The mechanism does not involve direct ion‑channel blockade or GABA‑receptor agonism, which distinguishes it from many older seizure medicines.

The appropriate dose of Levetiracetam Tarbis is determined by the prescribing clinician based on the patient’s age, weight, renal function, and severity of the seizure disorder. Dosage regimens are individualized, and the medication should be administered only under medical supervision in accordance with the physician’s instructions.

Safety data for levetiracetam in pregnancy are limited, and the drug is classified as pregnancy category unknown. It should be used only if the potential benefit to the mother outweighs any possible risk to the fetus. Likewise, because the extent of excretion in breast milk is not well established, caution is advised for nursing mothers.

To place an order, visit the product page on gnhindia.com, submit an enquiry with the required quantity, and provide institutional or trade credentials. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming pricing, availability, shipping conditions (including cold‑chain handling if needed), and any necessary import documentation before finalizing the sale.

Compared with older antiepileptics such as carbamazepine or phenytoin, levetiracetam has a distinct mechanism targeting SV2A and generally exhibits fewer drug‑enzyme interactions. It is often preferred for patients who experience adverse effects from enzyme‑inducing agents, though individual response varies and treatment choice should be guided by the clinician based on seizure type and patient profile.

Levetiracetam Tarbis must be stored at 2‑8 °C in a refrigerator. The solution should be kept in its original container, protected from light, and must not be frozen or shaken vigorously. Maintaining the cold‑chain ensures stability and potency until the product is prepared for intravenous administration.

The medication is supplied as a sterile injectable solution for intravenous infusion. It is administered by a qualified healthcare professional, typically as a slow infusion over several minutes, according to the dosing instructions provided by the prescriber. Proper aseptic technique and infusion equipment are required to ensure safe delivery.

The most serious adverse reactions include severe allergic responses such as anaphylaxis, significant mood or behavioral changes including depression or suicidal ideation, hematologic abnormalities like low blood cell counts, and rare dermatologic conditions such as Stevens‑Johnson syndrome. Patients should be monitored closely for any of these signs, and treatment should be discontinued if a serious reaction occurs.

Levetiracetam Tarbis is contraindicated in patients with known hypersensitivity to levetiracetam or any component of the formulation. Caution is also advised for individuals with severe renal impairment who have not had dose adjustments, and for those with a history of serious psychiatric disorders unless closely monitored. Pregnant or nursing women should only use it when clearly indicated and after thorough risk‑benefit assessment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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