Product image of Levetiracetam Tarbis (Levetiracetam) supplied by GNH India

Levetiracetam Tarbis

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Tarbis (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Tarbis, is an anticonvulsant presented as an oral tablet for oral use. It is used to treat epilepsy, including partial seizures and generalized tonic‑clonic seizures, in adult and pediatric patients as prescribed by a healthcare professional.

GNH India supplies Levetiracetam Tarbis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation to support import and distribution. Customers benefit from reliable supply chains and responsive technical support.

Manufacturer / TM Owner

Tarbis Farma, S.L.

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Indications & Clinical Uses

Levetiracetam is an antiepileptic medication that acts on synaptic vesicle protein SV2A to reduce neuronal hyperexcitability, thereby helping to control various seizure types.

  • Epilepsy: provides broad seizure control across multiple seizure types.
  • Partial seizures: reduces frequency and severity of focal onset seizures.
  • Generalized tonic‑clonic seizures: prevents occurrence of bilateral convulsive episodes.
  • Adjunct therapy: can be added to other antiepileptics when monotherapy is insufficient.

How It Works

  • Levetiracetam binds selectively to the synaptic vesicle protein SV2A, a component involved in neurotransmitter release. This interaction modulates calcium‑dependent exocytosis, stabilizing synaptic transmission and decreasing excessive neuronal firing. By reducing the release of excitatory neurotransmitters, the drug lowers the likelihood of synchronous neuronal discharges that generate seizures.

Side Effects

Levetiracetam may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Dizziness
  • Fatigue
  • Somnolence
  • Headache
  • Irritability
  • Nausea

Serious or Rare Side Effects

  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Depression or emergence of suicidal thoughts
  • Blood dyscrasias including neutropenia or thrombocytopenia
  • Multi‑organ hypersensitivity syndrome
  • Severe allergic reactions with angioedema
  • Hepatic injury (rare)

Precautions & Warnings

When prescribing levetiracetam, clinicians should consider several precautionary measures to ensure safe use.

  • Renal impairment: adjust dose based on creatinine clearance.
  • Hepatic dysfunction: monitor liver function tests regularly.
  • Pregnancy: risk unknown; use only if benefit outweighs potential risk.
  • Abrupt discontinuation: taper gradually to avoid seizure worsening.
  • Concomitant CNS depressants: use with caution due to additive sedation.
  • Store at ambient temperature: keep below 25 °C in original packaging, protect from moisture.

Avoid Interactions

Levetiracetam can interact with other medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid)

  • Carbamazepine: strong enzyme inducer that markedly reduces levetiracetam plasma levels.
  • Phenytoin: induces metabolism, potentially decreasing seizure control.
  • Phenobarbital: enhances clearance, leading to subtherapeutic concentrations.

Moderate Interactions (Monitor Closely)

  • Valproic acid: may increase levetiracetam levels, requiring dose adjustment.
  • Alcohol: can potentiate central nervous system depression and dizziness.

Frequently Asked Questions

Levetiracetam Tarbis is an oral antiepileptic medication indicated for the treatment of epilepsy, including partial (focal) seizures and generalized tonic‑clonic seizures. It helps to reduce the frequency and severity of seizure episodes in patients diagnosed with these seizure types.

Levetiracetam exerts its effect by binding to the synaptic vesicle protein SV2A, which plays a key role in neurotransmitter release. This binding modulates calcium‑dependent exocytosis, stabilizing synaptic activity and decreasing excessive neuronal firing that can trigger seizures.

The appropriate dose of levetiracetam is individualized by the prescribing clinician based on factors such as the patient’s age, weight, renal function, seizure type, and response to therapy. Dosage adjustments may be required for patients with impaired kidney function.

The safety of levetiracetam in pregnancy and lactation has not been definitively established. It is classified as pregnancy category unknown, so it should be used only when the potential benefit justifies any potential risk to the fetus. Breastfeeding mothers should discuss risks with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity of Levetiracetam Tarbis. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levetiracetam is often compared with other antiepileptics such as carbamazepine or valproic acid. Unlike many older agents, it has a relatively favorable drug‑interaction profile and does not require routine therapeutic drug monitoring. However, individual response and tolerability vary, so clinicians choose the agent best suited to the patient’s seizure type and comorbidities.

Levetiracetam Tarbis should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in their original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Levetiracetam Tarbis is taken orally, usually with or without food, as directed by the prescribing physician. The tablets are swallowed whole with a glass of water. Patients should follow the dosing schedule provided by their healthcare professional and not alter the regimen without medical advice.

Serious adverse reactions, though uncommon, include severe skin reactions (e.g., Stevens‑Johnson syndrome), significant mood changes such as depression or suicidal thoughts, blood disorders like neutropenia, and rare multi‑organ hypersensitivity. Patients should seek immediate medical attention if they notice rash, mood alterations, unexplained bruising or signs of infection.

Levetiracetam is contraindicated in individuals with known hypersensitivity to levetiracetam or any of its excipients. Caution is advised for patients with severe renal impairment, as dose adjustment is required, and for those with a history of psychiatric disorders, given the potential for mood changes.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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