Product image of Levetiracetam Teva (Levetiracetam) supplied by GNH India

Levetiracetam Teva

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Teva (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Teva, is an anticonvulsant presented as an intravenous solution for intravenous use. It treats epilepsy, including partial‑onset seizures and generalized tonic‑clonic seizures, in patients who require parenteral therapy.

GNH India supplies Levetiracetam Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Italia S.R.L.

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Indications & Clinical Uses

  • Levetiracetam is an antiepileptic drug used to control seizure activity across several epilepsy syndromes.
  • Partial‑onset seizures: reduces seizure frequency in patients with focal epilepsy.
  • Generalized tonic‑clonic seizures: helps control convulsive episodes in generalized epilepsy.
  • Epilepsy (overall): provides adjunctive therapy for patients with refractory seizures.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilising neuronal membranes. This interaction reduces excessive neuronal firing and hyperexcitability, thereby diminishing the propagation of epileptic discharges throughout the central nervous system.

Side Effects

Levetiracetam may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Fatigue
  • Dizziness
  • Somnolence
  • Headache
  • Irritability
  • Nausea

Serious or Rare Side Effects

  • Severe allergic reactions (anaphylaxis)
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Blood dyscrasias (e.g., neutropenia, thrombocytopenia)
  • Severe depression or suicidal thoughts
  • Respiratory depression (rare)
  • Hepatic failure (very rare)

Precautions & Warnings

When prescribing levetiracetam, clinicians should consider several safety aspects.

  • Renal impairment: adjust dose based on creatinine clearance.
  • Hepatic dysfunction: monitor liver enzymes regularly.
  • Psychiatric symptoms: observe for mood changes, depression, or suicidal ideation.
  • Concomitant CNS depressants: use caution as additive sedation may occur.
  • Pregnancy and lactation: risk unknown; weigh benefits against potential fetal exposure.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Levetiracetam can interact with other medicines, influencing its efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine: may lower levetiracetam plasma concentrations.
  • Enzyme‑inducing antiepileptics (phenytoin, phenobarbital): can reduce therapeutic effect.
  • Strong CYP3A4 inhibitors: potential increase in levetiracetam levels, requiring monitoring.

Moderate Interactions (Monitor Closely)

  • Alcohol: may enhance central nervous system depression.
  • Valproate: may require dose adjustment of levetiracetam.
  • Aminoglycoside antibiotics: competition for renal excretion pathways.

Frequently Asked Questions

Levetiracetam Teva is indicated for the treatment of epilepsy, specifically for patients with partial‑onset seizures and generalized tonic‑clonic seizures who require an intravenous antiepileptic therapy.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This action stabilises neuronal firing and reduces hyperexcitability, thereby limiting the spread of seizure activity in the brain.

The dosage of Levetiracetam Teva is determined by the prescribing clinician based on the patient’s age, weight, renal function, and clinical response. No fixed regimen is provided here.

Safety data for levetiracetam in pregnancy and lactation are limited. Clinicians should evaluate the potential benefits against possible risks and consider alternative therapies when appropriate.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and import documentation.

Levetiracetam offers a distinct mechanism by targeting SV2A, which differs from sodium‑channel blockers like carbamazepine. It generally has fewer drug‑enzyme interactions, but clinicians must still assess individual patient factors and seizure type when selecting therapy.

Store the intravenous solution at room temperature, preferably below 25 °C. Keep the vial in its original packaging, protect it from light, and avoid moisture exposure to maintain stability.

Levetiracetam Teva is given as an intravenous infusion. The rate and duration of infusion are set by the healthcare professional according to the prescribed dose and patient tolerance.

Serious adverse events include severe allergic reactions such as anaphylaxis, skin disorders like Stevens‑Johnson syndrome, blood dyscrasias, and rare cases of severe depression or suicidal thoughts. Prompt medical evaluation is required if these occur.

Patients with known hypersensitivity to levetiracetam or any component of the formulation should avoid its use. Caution is also advised for individuals with severe renal impairment unless dose adjustments are made.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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