Product image of Levetiracetam Teva (Levetiracetam) supplied by GNH India

Levetiracetam Teva

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Teva (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Teva, is an anticonvulsant presented as an injectable solution for intravenous use. It is employed as adjunctive therapy for partial‑onset seizures and generalized tonic‑clonic seizures in patients with epilepsy.

GNH India supplies Levetiracetam Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality‑assured products for the global market. The company follows EU GMP standards and offers reliable cold‑chain logistics for injectable medicines, supporting timely delivery to healthcare providers.

Manufacturer / TM Owner

Teva Nederland B.V.

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Indications & Clinical Uses

Levetiracetam is an antiepileptic medication that modulates neuronal excitability in seizure disorders.

  • Partial‑onset seizures: reduces seizure frequency as an adjunct to existing antiepileptic therapy.
  • Generalized tonic‑clonic seizures: provides additional seizure control when combined with other agents.
  • Refractory epilepsy: offers an alternative option for patients whose seizures are not adequately controlled by other medications.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, a key regulator of neurotransmitter release. This interaction modulates calcium‑dependent exocytosis, stabilizing neuronal membranes and decreasing hyper‑synchronous firing. By reducing the release of excitatory neurotransmitters, the drug lowers neuronal excitability, thereby helping to prevent the initiation and spread of epileptic seizures. The precise downstream pathways remain under investigation, but the overall effect contributes to seizure suppression without significant interaction with ion channels.

Side Effects

Levetiracetam may be associated with a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Dizziness
  • Somnolence
  • Fatigue
  • Irritability

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis)
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Suicidal thoughts or behavior

Precautions & Warnings

When using Levetiracetam injectable solution, several precautions should be observed to ensure patient safety.

  • Renal impairment: adjust dose based on creatinine clearance.
  • Hepatic impairment: monitor liver function tests and consider dose modification.
  • Concomitant CNS depressants: increased risk of sedation and respiratory depression.
  • Pregnancy: safety category unknown; weigh potential benefits against risks.
  • Behavioral changes: monitor for aggression, mood swings, or suicidal ideation.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Levetiracetam can interact with other medicines, influencing its efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine: enzyme induction may lower levetiracetam plasma levels.
  • Phenobarbital: reduces levetiracetam concentrations, potentially decreasing effectiveness.
  • Phenytoin: may decrease levetiracetam exposure, risking breakthrough seizures.

Moderate Interactions (Monitor Closely)

  • Valproic acid: may increase risk of central nervous system side effects.
  • Alcohol or other CNS depressants: enhanced sedation and respiratory depression.

Frequently Asked Questions

Levetiracetam Teva is an injectable antiepileptic indicated for use as adjunctive therapy in patients with partial‑onset seizures and generalized tonic‑clonic seizures. It is prescribed when additional seizure control is needed alongside other antiepileptic medications.

Levetiracetam binds to the synaptic vesicle protein SV2A, modulating calcium‑dependent neurotransmitter release. This action stabilizes neuronal membranes, reduces excitatory signaling, and lowers the likelihood of hyper‑synchronous neuronal firing that underlies epileptic seizures.

The dosing regimen for Levetiracetam Teva is individualized. A qualified prescriber determines the appropriate dose, infusion rate, and treatment duration based on the patient’s clinical condition, age, renal function, and response to therapy.

Levetiracetam is classified with an unknown pregnancy category, meaning safety data are limited. Clinicians must weigh potential benefits against possible risks, and breastfeeding mothers should consult their healthcare provider before using the product.

To place an order, submit an enquiry on the Levetiracetam Teva product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Levetiracetam has a distinct mechanism targeting SV2A, which differs from sodium‑channel blockers or GABA‑enhancers. It is generally well tolerated, has minimal drug‑enzyme interactions, and does not require routine therapeutic monitoring, making it a convenient option compared with many older antiepileptics.

Levetiracetam Teva must be stored refrigerated between 2 °C and 8 °C. Keep the vials in their original packaging, protect them from light, and avoid freezing or shaking the solution. If temperature excursions occur, consult the supplier before use.

The product is supplied as an injectable solution for intravenous infusion. Administration is performed by a qualified healthcare professional, typically over a short infusion period as directed by the prescribing physician, with appropriate aseptic technique and monitoring.

Serious adverse events include severe allergic reactions such as anaphylaxis, life‑threatening skin conditions like Stevens‑Johnson syndrome, and the emergence of suicidal thoughts or behaviors. Prompt medical attention is required if any of these symptoms develop.

Patients with known hypersensitivity to levetiracetam or any component of the injectable formulation should avoid its use. Caution is also advised for individuals with severe renal impairment, uncontrolled psychiatric conditions, or those taking interacting enzyme‑inducing antiepileptics without appropriate dose adjustment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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