Product image of Levetiracetam Teva (Levetiracetam) supplied by GNH India

Levetiracetam Teva

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Teva (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Teva, is an antiepileptic presented as an oral dosage form for oral use. It is prescribed to control partial, generalized tonic‑clonic and myoclonic seizures in patients with epilepsy. It is indicated for use in both adult and pediatric populations, with dosing individualized by the treating physician.

GNH India supplies Levetiracetam Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for bulk and parcel orders across multiple regulatory jurisdictions.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Levetiracetam is an antiepileptic drug that reduces neuronal excitability and is used to manage several seizure types.

  • Partial seizures: reduces frequency and severity of focal onset seizures.
  • Generalized tonic‑clonic seizures: helps achieve seizure freedom or significant reduction in convulsive episodes.
  • Myoclonic seizures: controls sudden muscle jerks and improves daily functioning.

How It Works

  • Levetiracetam binds selectively to the synaptic vesicle protein SV2A, a regulator of neurotransmitter release. This interaction modulates calcium‑dependent exocytosis, stabilizing synaptic transmission and decreasing neuronal hyper‑excitability. By influencing SV2A, the drug reduces the likelihood of abnormal electrical discharges that underlie epileptic seizures without significant interaction with traditional ion‑channel targets. It does not significantly affect GABAergic or glutamatergic receptor activity, contributing to its favorable safety profile.

Side Effects

Levetiracetam may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Dizziness
  • Fatigue
  • Somnolence
  • Irritability
  • Headache
  • Nausea

Serious or Rare Side Effects

  • Severe allergic reactions (e.g., angioedema, anaphylaxis)
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Suicidal thoughts or behavior
  • Blood dyscrasias (e.g., neutropenia, thrombocytopenia)

Precautions & Warnings

When prescribing Levetiracetam, clinicians should consider several safety measures to minimize risk.

  • Renal function: assess baseline and adjust dose in renal impairment.
  • Pregnancy: use only if benefit outweighs risk; category C.
  • Psychiatric disorders: monitor for mood changes or aggression.
  • Discontinuation: taper gradually to avoid seizure exacerbation.
  • Concomitant CNS depressants: use with caution due to additive sedation.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Levetiracetam can interact with other medicines, affecting its plasma concentration or enhancing side effects.

Major Interactions (Avoid)

  • Carbamazepine: induces metabolism, reducing levetiracetam levels.
  • Phenobarbital: enzyme induction leading to lower levetiracetam exposure.
  • Phenytoin: decreases levetiracetam concentrations through hepatic induction.

Moderate Interactions (Monitor Closely)

  • Alcohol: may increase CNS depression and dizziness.
  • Hormonal contraceptives: levetiracetam may reduce contraceptive efficacy; consider alternative methods.
  • Other antiepileptics: additive side‑effects such as increased fatigue or behavioral changes.

Frequently Asked Questions

Levetiracetam Teva is prescribed to treat epilepsy by controlling partial seizures, generalized tonic‑clonic seizures, and myoclonic seizures. It helps reduce the frequency and intensity of seizure episodes, improving overall neurological stability for both adult and pediatric patients.

Levetiracetam exerts its effect by binding to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This action stabilizes synaptic transmission, lowers neuronal hyper‑excitability, and diminishes the likelihood of abnormal electrical discharges that trigger seizures.

The dose of Levetiracetam Teva is individualized by the prescribing clinician. Factors such as patient age, weight, renal function, seizure type, and response to therapy guide the selection of an appropriate dosing regimen.

Levetiracetam is classified as Pregnancy Category C, meaning risk cannot be ruled out and it should only be used when the potential benefit justifies the potential risk to the fetus. Limited data are available for breastfeeding, so a risk‑benefit assessment is required before use.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with many traditional antiepileptics, Levetiracetam has a unique SV2A‑targeted mechanism, a relatively low potential for drug‑enzyme interactions, and a generally favorable safety profile. However, individual response varies, and clinicians consider factors such as seizure type, comorbidities and tolerability when selecting therapy.

Levetiracetam Teva should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight and excessive heat to maintain potency and stability.

Levetiracetam is administered orally, typically as tablets or oral solution, and taken with or without food. The exact route and frequency are determined by the prescriber based on the patient’s clinical needs.

Serious risks include severe allergic reactions such as angioedema or anaphylaxis, rare skin conditions like Stevens‑Johnson syndrome, and neuropsychiatric events including suicidal thoughts or behavior. Prompt medical attention is required if any of these occur.

Levetiracetam is contraindicated in individuals with known hypersensitivity to the drug or any of its excipients. Caution is also advised for patients with severe renal impairment, uncontrolled psychiatric disorders, or those who are pregnant without a clear therapeutic justification.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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