Product image of Levetiracetam Ucb (Levetiracetam) supplied by GNH India

Levetiracetam Ucb

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Ucb (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Ucb, is an antiepileptic presented as an oral tablet for oral use. It is employed to control partial, generalized tonic‑clonic and myoclonic seizures in patients with epilepsy across various age groups.

GNH India supplies Levetiracetam Ucb as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable access to quality‑assured medication for seizure management. The company adheres to stringent quality standards, ensuring product integrity throughout the supply chain, and supports regulatory compliance for global distribution.

Manufacturer / TM Owner

Ucb Pharma (Produtos Farmacêuticos) Lda.

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Indications & Clinical Uses

  • Levetiracetam is an antiepileptic drug used to treat several seizure types by stabilizing neuronal activity.
  • Partial seizures: decreases the number of focal onset seizures and helps achieve better seizure control in patients with localized epilepsy.
  • Generalized tonic‑clonic seizures: suppresses bilateral convulsive activity, reducing the occurrence of full‑body shaking episodes in generalized epilepsy.
  • Myoclonic seizures: lessens sudden, brief muscle jerks, improving daily functioning for individuals with myoclonic epilepsy.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal firing. This interaction reduces excessive synaptic transmission, thereby lowering neuronal excitability and preventing the propagation of seizure activity across neural networks. The precise mechanism is not fully understood, but the SV2A binding is thought to influence calcium‑dependent vesicle exocytosis, contributing to its broad‑spectrum anticonvulsant effect without significant interaction with GABA or glutamate receptors.

Side Effects

Levetiracetam may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Dizziness
  • Fatigue
  • Headache
  • Irritability
  • Nausea
  • Nasal congestion

Serious or Rare Side Effects

  • Severe allergic reactions (anaphylaxis)
  • Mood changes including depression or suicidal thoughts
  • Blood disorders such as neutropenia or thrombocytopenia
  • Stevens‑Johnson syndrome
  • Hepatic injury

Precautions & Warnings

  • When prescribing Levetiracetam, clinicians should consider several safety factors.
  • Renal impairment: dose may need adjustment in patients with reduced kidney function.
  • Hepatic dysfunction: monitor liver enzymes, especially in patients with existing liver disease.
  • Psychiatric symptoms: observe for mood changes, depression, or aggression.
  • Concomitant CNS depressants: use caution as combined effects may increase sedation.
  • Pregnancy and lactation: safety not established; weigh benefits against potential risks.
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Levetiracetam can interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Carbamazepine: may lower levetiracetam plasma levels, decreasing seizure control.
  • Phenobarbital: can reduce levetiracetam concentrations, necessitating close monitoring.

Moderate Interactions (Monitor Closely)

  • Alcohol: may enhance central nervous system depression and dizziness.
  • Other antiepileptic drugs (e.g., valproate): may require dose adjustments.
  • Oral contraceptives: levetiracetam may slightly reduce hormonal efficacy; consider alternative contraception.

Frequently Asked Questions

Levetiracetam Ucb is used to treat epilepsy by reducing the frequency of partial, generalized tonic‑clonic, and myoclonic seizures. It is prescribed for patients who require an oral antiepileptic medication to achieve better seizure control.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This action stabilizes neuronal firing, lowers excessive excitability, and helps prevent the spread of seizure activity throughout the brain.

The dosage of Levetiracetam Ucb is individualized. A qualified prescriber determines the appropriate dose based on the patient’s age, weight, renal function, and seizure type, and may adjust it over time according to therapeutic response.

Safety data for levetiracetam in pregnancy and lactation are limited. The drug is classified as pregnancy category unknown, so clinicians must weigh potential benefits against possible risks and discuss options with the patient.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levetiracetam offers a broad spectrum of seizure control with a relatively low potential for drug‑enzyme interactions, unlike many older agents such as carbamazepine or phenytoin. It is often chosen for its favorable pharmacokinetic profile and ease of dosing, though individual response varies.

Levetiracetam Ucb tablets should be stored below 25 °C in their original packaging, protected from moisture and direct sunlight. Keep the container tightly closed and out of reach of children.

Levetiracetam Ucb is taken orally, usually with or without food, as directed by the prescribing physician. Tablets are swallowed whole with water; the exact schedule (once, twice, or multiple times daily) depends on the individualized dosing plan.

Serious risks include severe allergic reactions (anaphylaxis), mood alterations such as depression or suicidal thoughts, and rare blood disorders like neutropenia. Patients should report any sudden behavioral changes, rash, or signs of infection to their healthcare provider promptly.

Levetiracetam is contraindicated in individuals with known hypersensitivity to levetiracetam or any of its excipients. Caution is advised for patients with severe renal impairment, uncontrolled psychiatric conditions, or those taking interacting medications that may diminish its effectiveness.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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