Product image of Levetiracetam Viatris (Levetiracetam) supplied by GNH India

Levetiracetam Viatris

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Viatris (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Viatris, is an anticonvulsant presented as an oral tablet for oral use. It is indicated for adjunctive therapy in various seizure types and is prescribed for patients with epilepsy who require additional seizure control.
GNH India supplies Levetiracetam Viatris as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Viatris Limited

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Indications & Clinical Uses

Levetiracetam is an antiepileptic drug used to manage seizure disorders. It is employed as an adjunctive therapy in the following conditions:

  • Partial‑onset seizures: reduces the frequency of focal seizures when added to existing therapy.
  • Generalized tonic‑clonic seizures: helps control convulsive seizures in patients with refractory epilepsy.
  • Myoclonic seizures: diminishes myoclonic jerks as part of combination treatment.

How It Works

  • Levetiracetam binds selectively to the synaptic vesicle protein SV2A, a key regulator of neurotransmitter release. This interaction modulates synaptic transmission, decreasing excessive neuronal firing and stabilizing neuronal networks, which contributes to its antiepileptic effect without directly influencing ion channels or GABA receptors.

Side Effects

Levetiracetam may cause a range of adverse reactions, most of which are mild to moderate in severity.

Common Side Effects

  • Dizziness: transient sensation of light‑headedness.
  • Fatigue: generalized tiredness or lack of energy.
  • Headache: mild to moderate cranial pain.
  • Irritability: mood changes or increased agitation.
  • Nausea: occasional stomach upset.
  • Nasal congestion: mild blockage of nasal passages.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Mood disorders: depression, suicidal thoughts, or severe anxiety.
  • Hematologic abnormalities: low blood cell counts.
  • Liver enzyme elevation: signs of hepatic stress.
  • Skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Multiorgan hypersensitivity: systemic involvement requiring urgent care.

Precautions & Warnings

When prescribing Levetiracetam, clinicians should consider several safety aspects.

  • Renal function: adjust dose in patients with impaired clearance.
  • Pregnancy: Category B, use only if benefits outweigh risks.
  • Breastfeeding: monitor infant for sedation or irritability.
  • Psychiatric history: observe for mood changes or suicidal ideation.
  • Concomitant CNS depressants: assess for additive sedation.
  • Store at ambient temperature: keep below 25 °C, retain original packaging, and protect from moisture.

Avoid Interactions

Levetiracetam has a relatively low potential for drug‑drug interactions, but certain combinations require attention.

Major Interactions (Avoid)

  • Carbamazepine: may reduce levetiracetam plasma levels.
  • Phenobarbital: can lower levetiracetam concentrations.

Moderate Interactions (Monitor Closely)

  • Valproic acid: may increase levetiracetam exposure.
  • Topiramate: additive CNS side effects such as dizziness.
  • Alcohol: enhanced sedation and impairment.
  • Other antiepileptics: monitor overall seizure control and side‑effect profile.

Frequently Asked Questions

Levetiracetam Viatris is an oral antiepileptic medication used as adjunctive therapy for partial‑onset seizures, generalized tonic‑clonic seizures, and myoclonic seizures in patients with epilepsy who need additional seizure control.

Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and reducing excessive neuronal firing. This stabilizes neuronal networks and helps prevent the spread of seizure activity without directly affecting ion channels or GABA receptors.

The dosage of Levetiracetam Viatris is individualized by the prescribing clinician based on the patient’s age, renal function, seizure type, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Levetiracetam is classified as Pregnancy Category B, indicating no evidence of fetal risk in animal studies but a lack of well‑controlled human data. It may be used during pregnancy if the potential benefit justifies the risk. Small amounts are excreted in breast milk; breastfeeding mothers should discuss risks and benefits with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Levetiracetam offers a favorable safety profile with minimal enzyme‑inducing properties, reducing the likelihood of drug‑drug interactions compared with many older antiepileptics such as carbamazepine or phenytoin. Its unique SV2A binding mechanism provides effective seizure control, especially in patients who have not responded to other therapies.

Levetiracetam Viatris tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments.

Levetiracetam Viatris is taken orally, usually with or without food, as directed by the prescriber. Tablets should be swallowed whole with water and not chewed or crushed unless specifically instructed.

Serious risks include severe allergic reactions (e.g., rash, swelling, breathing difficulty), mood disturbances such as depression or suicidal thoughts, and rare hematologic abnormalities. Patients should seek immediate medical attention if they experience any of these symptoms.

Levetiracetam is contraindicated in patients with known hypersensitivity to levetiracetam or any of its excipients. Caution is advised for individuals with severe renal impairment, uncontrolled psychiatric conditions, or those taking interacting medications that may significantly alter its efficacy.

Published by

GNH India Pharmaceuticals Limited

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Last updated:

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