Product image of Levetiracetam Vir (Levetiracetam) supplied by GNH India

Levetiracetam Vir

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Vir (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Vir, is an anticonvulsant (pyrrolidine derivative) presented as an oral dosage form for oral use. It treats partial seizures and generalized tonic‑clonic seizures in patients with epilepsy.

GNH India supplies Levetiracetam Vir as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Industria Química Y Farmaceútica Vir, S.A.

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Indications & Clinical Uses

  • Levetiracetam is an anticonvulsant used to manage seizure disorders.
  • Partial seizures: reduces the frequency of focal onset seizures.
  • Generalized tonic‑clonic seizures: helps control primary generalized seizures.
  • Adjunct therapy in epilepsy: used alongside other antiepileptic drugs to improve overall seizure control.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal membranes. This interaction reduces excessive neuronal firing, thereby decreasing seizure activity without directly affecting ion channels or GABA receptors.

Side Effects

Levetiracetam may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Dizziness
  • Fatigue or somnolence
  • Headache
  • Irritability or mood changes
  • Nausea or gastrointestinal discomfort

Serious or Rare Side Effects

  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Suicidal thoughts or behavior
  • Major depressive episodes
  • Blood dyscrasias (e.g., neutropenia, thrombocytopenia)
  • Hypersensitivity reactions including anaphylaxis
  • Rhabdomyolysis or muscle breakdown

Precautions & Warnings

  • When prescribing Levetiracetam, clinicians should consider several safety aspects.
  • Renal impairment: adjust dose based on renal function.
  • Hepatic impairment: monitor liver enzymes and consider dose modification.
  • Psychiatric symptoms: observe for mood changes, depression, or suicidal ideation.
  • Pregnancy: risk category unknown; discuss potential benefits and risks with the patient.
  • Concomitant CNS depressants: may increase sedation, monitor patient response.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Levetiracetam can interact with other medicines, influencing its effectiveness or safety.

Major Interactions (Avoid)

  • Carbamazepine: may lower levetiracetam plasma levels.
  • Phenobarbital: may reduce levetiracetam exposure.
  • Phenytoin: may decrease levetiracetam concentrations.

Moderate Interactions (Monitor Closely)

  • Alcohol: can enhance central nervous system depression.
  • Other antiepileptic drugs: may require dose adjustments for optimal seizure control.
  • Renal excretion inhibitors: monitor renal function and consider dose changes.

Frequently Asked Questions

Levetiracetam Vir is a prescription antiepileptic medication used to treat partial (focal) seizures and generalized tonic‑clonic seizures in patients diagnosed with epilepsy. It may be prescribed as monotherapy or as part of a combination regimen to improve seizure control.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. By influencing this protein, the drug stabilizes neuronal activity and reduces the likelihood of excessive firing that leads to seizures, without directly altering ion channels or GABA activity.

The specific dosage of Levetiracetam Vir is determined by the prescribing clinician based on the patient’s age, weight, renal function, seizure type, and response to therapy. Patients should follow the dose prescribed by their healthcare professional and not adjust it independently.

The safety of Levetiracetam in pregnancy and lactation has not been definitively established. Healthcare providers weigh potential benefits against possible risks, and women who are pregnant, planning pregnancy, or breastfeeding should discuss treatment options with their physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Levetiracetam offers a distinct mechanism by targeting SV2A, which can provide effective seizure control with a relatively favorable interaction profile compared with enzyme‑inducing agents like carbamazepine or phenytoin. Its once‑ or twice‑daily dosing and limited hepatic metabolism make it a convenient option for many patients.

Levetiracetam Vir should be stored at ambient temperature, below 25 °C, in its original container to protect it from moisture and light. Keep the product out of reach of children and avoid storing in areas with high humidity or extreme temperatures.

Levetiracetam Vir is taken orally, usually with or without food, as directed by the prescribing physician. Tablets should be swallowed whole with water; they are not intended for crushing, chewing, or splitting unless specifically advised by a healthcare professional.

Serious risks include severe skin reactions such as Stevens‑Johnson syndrome, suicidal thoughts or behaviors, major depressive episodes, and rare blood disorders. Patients should promptly report any rash, mood changes, or unusual symptoms to their healthcare provider.

Levetiracetam Vir is contraindicated in individuals with known hypersensitivity to levetiracetam or any of its excipients. Caution is advised for patients with severe renal impairment, uncontrolled psychiatric conditions, or those taking medications that significantly reduce levetiracetam levels without appropriate monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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