Product image of Levetiracetam Zentiva (Levetiracetam) supplied by GNH India

Levetiracetam Zentiva

Active Ingredient:
Levetiracetam
Origin:
EU

Levetiracetam Zentiva (Levetiracetam)

Levetiracetam, the active ingredient in Levetiracetam Zentiva, is an anticonvulsant presented as a tablet for oral use. It is used to treat various seizure types in patients with epilepsy.
GNH India supplies Levetiracetam Zentiva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Zentiva Pharma Gmbh

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Indications & Clinical Uses

Levetiracetam is an antiepileptic medication that acts on neuronal excitability to control seizure activity.

  • Partial seizures: reduces the frequency and severity of focal onset seizures.
  • Generalized tonic‑clonic seizures: helps prevent convulsive episodes.
  • Myoclonic seizures: diminishes sudden muscle jerks associated with this seizure type.

How It Works

  • Levetiracetam binds to the synaptic vesicle protein SV2A, modulating neurotransmitter release and stabilizing neuronal membranes. This interaction decreases abnormal neuronal firing, thereby reducing the likelihood of seizure propagation across the central nervous system.

Side Effects

Levetiracetam may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Drowsiness: feeling unusually sleepy or fatigued.
  • Dizziness: sensation of light‑headedness or unsteadiness.
  • Headache: mild to moderate cranial pain.
  • Irritability: increased mood swings or agitation.
  • Nausea: upset stomach or feeling of queasiness.
  • Nasal congestion: blocked or runny nose.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Mood changes: depression, suicidal thoughts, or aggressive behavior.
  • Blood disorders: signs of anemia or low white blood cell count.
  • Liver dysfunction: jaundice or abnormal liver enzyme levels.
  • Skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Renal function: adjust dose in patients with impaired kidney function.
  • Psychiatric history: monitor for mood alterations or suicidal ideation.
  • Pregnancy: discuss potential risks with a healthcare professional.
  • Breastfeeding: evaluate benefits versus potential infant exposure.
  • Concomitant CNS depressants: use caution as additive sedation may occur.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture.

Avoid Interactions

Levetiracetam can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid)

  • Carbamazepine: may reduce levetiracetam plasma levels.
  • Phenobarbital: may decrease levetiracetam exposure.

Moderate Interactions (Monitor Closely)

  • Valproic acid: potential for increased adverse effects.
  • Fluconazole: may modestly raise levetiracetam concentrations.
  • Oral contraceptives: monitor for reduced contraceptive effectiveness.
  • Other antiepileptics: assess for additive CNS depression.
  • Alcohol: may enhance drowsiness and dizziness.

Frequently Asked Questions

Levetiracetam Zentiva is prescribed to manage partial (focal) seizures, generalized tonic‑clonic seizures, and myoclonic seizures in patients diagnosed with epilepsy. It helps reduce seizure frequency and severity by stabilizing neuronal activity.

Levetiracetam binds to the synaptic vesicle protein SV2A, which modulates neurotransmitter release. This action dampens excessive neuronal firing, thereby decreasing the propagation of seizure activity throughout the brain.

The appropriate dose of Levetiracetam Zentiva is determined individually by a prescriber based on the patient’s age, weight, renal function, and seizure type. Dosage adjustments are made to achieve optimal seizure control while minimizing side effects.

Safety data for levetiracetam in pregnancy and lactation are limited. Healthcare providers should evaluate the potential benefits against possible risks before prescribing to pregnant or nursing individuals, and discuss alternative options when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Levetiracetam offers a favorable safety profile and minimal drug‑enzyme interactions compared with many older antiepileptics such as carbamazepine or phenytoin. Its once‑ or twice‑daily dosing and lack of routine blood‑level monitoring make it a convenient option for many patients.

Store Levetiracetam Zentiva tablets at ambient temperature, below 25 °C. Keep the product in its original container, protect it from moisture and direct sunlight, and ensure the packaging remains sealed until use.

Levetiracetam Zentiva is taken orally, usually with or without food. Tablets should be swallowed whole with a glass of water. The exact dosing schedule is set by the prescribing clinician.

Serious risks include severe allergic reactions (e.g., rash, swelling, breathing difficulty), mood changes such as depression or suicidal thoughts, and rare skin conditions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if any of these occur.

Individuals with known hypersensitivity to levetiracetam or any tablet excipients should avoid the product. Caution is also advised for patients with severe renal impairment, uncontrolled psychiatric disorders, or those taking interacting medications without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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