Product image of Leviaben (Levofloxacin) supplied by GNH India

Leviaben

Active Ingredient:
Levofloxacin
Origin:
EU

Leviaben (Levofloxacin)

Levofloxacin, the active ingredient in Leviaben, is a fluoroquinolone antibiotic presented as an oral tablet for oral use. It treats a broad range of bacterial infections in adults and children when prescribed by a qualified healthcare professional.

GNH India supplies Leviaben as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies, transplant centres and clinics worldwide under stringent quality assurance and regulatory standards. The company ensures reliable global logistics and supports customers with documentation for import and customs clearance.

Manufacturer / TM Owner

Krka, D.D., Novo Mesto

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Indications & Clinical Uses

Levofloxacin is a fluoroquinolone antibiotic used to treat bacterial infections in various organ systems.

  • Community‑Acquired Pneumonia: eradicates causative bacteria and improves respiratory symptoms.
  • Acute Bacterial Sinusitis: reduces sinus inflammation and clears infection.
  • Uncomplicated Urinary Tract Infection: eliminates uropathogens and resolves urinary symptoms.
  • Skin and Skin Structure Infections: treats cellulitis and other bacterial skin conditions.
  • Acute Bacterial Exacerbation of Chronic Bronchitis: controls bacterial overgrowth and improves breathing.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By binding to these enzymes, it prevents the supercoiling and separation of DNA strands, leading to bacterial cell death and cessation of infection spread.

Side Effects

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Dizziness: occasional light‑headedness.

Serious or Rare Side Effects

  • Tendon rupture: especially Achilles tendon, may occur without warning.
  • QT interval prolongation: risk of cardiac arrhythmias.
  • Severe allergic reactions: including anaphylaxis and Stevens‑Johnson syndrome.
  • Clostridioides difficile infection: severe colitis after antibiotic use.
  • Hepatic dysfunction: elevated liver enzymes or jaundice.
  • Anaphylaxis: rapid onset of life‑threatening hypersensitivity.

Precautions & Warnings

Levofloxacin requires careful consideration in certain patient groups and situations.

  • Renal impairment: dose adjustment may be required based on kidney function.
  • History of tendon disorders: avoid use due to increased risk of tendon rupture.
  • QT prolongation risk: monitor ECG in patients with cardiac arrhythmias.
  • Concomitant NSAIDs: may increase tendon injury risk.
  • Known hypersensitivity to fluoroquinolones: contraindicated.
  • Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Levofloxacin can interact with several medicines, affecting efficacy or safety.

Major Interactions (Avoid)

  • Antacids containing magnesium or aluminum: markedly reduce levofloxacin absorption.
  • Warfarin: may increase INR and bleeding risk.
  • Theophylline: levofloxacin can raise plasma theophylline levels.
  • Cyclosporine: increased cyclosporine concentrations may occur.

Moderate Interactions (Monitor Closely)

  • NSAIDs: heightened risk of central nervous system effects.
  • Oral hypoglycemics: possible alteration of blood glucose control.
  • Corticosteroids: combined use may raise tendon rupture risk.

Frequently Asked Questions

Leviaben contains levofloxacin, a fluoroquinolone antibiotic that is prescribed to treat a variety of bacterial infections such as pneumonia, sinusitis, urinary tract infections, skin infections, and exacerbations of chronic bronchitis when a qualified clinician determines it is appropriate.

Levofloxacin works by binding to bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for DNA replication and transcription. Inhibiting these enzymes prevents bacterial DNA from unwinding and replicating, leading to bacterial cell death and resolution of the infection.

The dosage of Leviaben is individualized by the prescribing healthcare professional based on the type and severity of the infection, patient age, weight, renal function, and other clinical factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of levofloxacin in pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To order Leviaben, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levofloxacin offers broad‑spectrum activity against Gram‑positive and Gram‑negative bacteria and has excellent oral bioavailability, often allowing oral therapy in place of intravenous treatment. Compared with older fluoroquinolones, it may have a more favorable dosing schedule but shares similar safety considerations.

Leviaben should be stored at ambient temperature, below 25 °C, in its original container to protect it from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged.

Leviaben is taken orally, usually with a full glass of water. It can be taken with or without food, but patients should avoid simultaneous intake of antacids containing magnesium or aluminum, as these can reduce absorption.

Serious risks include tendon rupture (especially Achilles tendon), QT interval prolongation leading to cardiac arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, and hepatic dysfunction. Patients should seek immediate medical attention if they experience any of these symptoms.

Leviaben should not be used by individuals with a known hypersensitivity to levofloxacin or any fluoroquinolone, patients with a history of tendon disorders related to fluoroquinolone use, and those with significant QT prolongation unless closely monitored by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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