Product image of Levina (Ethinylestradiol, Levonorgestrel) supplied by GNH India

Levina

Active Ingredient:
Ethinylestradiol, Levonorgestrel
Origin:
EU

Levina (Ethinylestradiol, Levonorgestrel)

Ethinylestradiol and Levonorgestrel, the active ingredients in Levina, are a combined oral contraceptive presented as tablets for oral use. This hormonal formulation works to prevent pregnancy by inhibiting ovulation, thickening cervical mucus, and altering the endometrium, and is indicated for use by women of reproductive age seeking reliable birth control. It provides a convenient once‑daily dosing schedule and is part of a well‑established class of estrogen‑progestin contraceptives that have been used worldwide for decades.

GNH India supplies Levina as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stadapharm Gmbh

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Indications & Clinical Uses

  • Levina, a combined oral contraceptive, is used to prevent pregnancy.
  • Contraception: prevents pregnancy in women of reproductive age.
  • Family planning: provides a reliable method for planned childbearing.
  • Menstrual regulation: helps achieve more predictable menstrual cycles.

How It Works

  • Ethinylestradiol and levonorgestrel act on the hypothalamic‑pituitary‑ovarian axis. Ethinylestradiol provides estrogenic feedback that suppresses follicle‑stimulating hormone, while levonorgestrel, a progestogen, inhibits luteinizing hormone surge, preventing ovulation. The progestin also thickens cervical mucus and induces endometrial changes that reduce the likelihood of implantation.

Side Effects

Levina may cause a range of adverse reactions. Common Side Effects:

  • Nausea: mild to moderate stomach upset.
  • Breast tenderness: temporary swelling or discomfort.
  • Headache: occasional tension‑type headaches.
  • Spotting: irregular bleeding between periods.

Serious or Rare Side Effects

  • Deep vein thrombosis: blood clot formation in leg veins.
  • Pulmonary embolism: clot migration to lung vessels.
  • Stroke or myocardial infarction: rare cardiovascular events.
  • Severe allergic reaction: rash, swelling, or breathing difficulty.
  • Liver tumor: very rare hepatic adenoma.

Precautions & Warnings

  • Before prescribing Levina, clinicians should consider several safety aspects.
  • Contraindications: avoid in women with a history of thromboembolic disorders.
  • Smoking: do not use in patients over 35 who smoke cigarettes.
  • Medication review: assess concurrent use of enzyme‑inducing drugs.
  • Pregnancy: discontinue immediately if pregnancy is confirmed.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Levina can interact with other medicines, altering its effectiveness or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin): may reduce contraceptive efficacy.
  • Certain antiretrovirals (e.g., efavirenz): can lower hormone levels.
  • St. John’s wort: may compromise birth control reliability.

Moderate Interactions (Monitor Closely)

  • Antifungal agents (ketoconazole, itraconazole): may increase hormone concentrations.
  • Antibiotics (rifabutin, griseofulvin): potential modest reduction in effectiveness.
  • Anticonvulsants (valproate): may require additional contraceptive measures.

Frequently Asked Questions

Levina is a combined oral contraceptive indicated for the prevention of pregnancy in women of reproductive age. It provides a reliable, reversible method of birth control when taken as prescribed, helping users plan families and manage menstrual cycles.

The estrogen component, ethinylestradiol, suppresses the release of follicle‑stimulating hormone, while the progestin component, levonorgestrel, blocks the luteinizing hormone surge needed for ovulation. Together they also thicken cervical mucus and alter the uterine lining, creating multiple barriers to fertilisation and implantation.

The dosing regimen for Levina is determined by the prescribing clinician. Typically, it is taken once daily at the same time each day, but the exact schedule, tablet strength and cycle length are set according to individual medical assessment.

Levina is not intended for use during an existing pregnancy and should be stopped if pregnancy occurs. While limited data exist for breastfeeding, most guidelines advise caution; women should discuss potential risks and benefits with their healthcare provider before using it while nursing.

To order Levina, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levina contains the widely used estrogen‑progestin pair ethinylestradiol and levonorgestrel, offering efficacy comparable to other second‑generation combined pills. Its safety profile, dosing convenience and extensive clinical experience make it a standard option alongside alternatives that may use different progestins or estrogen doses.

Levina tablets should be stored at ambient temperature, below 25 °C, in their original blister pack to protect from moisture and light. Keep the medication out of reach of children and do not use if the packaging is damaged or the tablets appear discoloured.

Levina is taken orally, usually one tablet each day, preferably at the same time each day. It is part of a 21‑day active tablet regimen followed by a hormone‑free interval, but the exact schedule is defined by the prescriber.

Serious risks include thromboembolic events such as deep‑vein thrombosis, pulmonary embolism, stroke, and myocardial infarction. Rare but severe allergic reactions and liver tumours have also been reported. Users should seek immediate medical attention if they experience unexplained leg pain, chest discomfort, severe headache, or signs of an allergic reaction.

Levina is contraindicated in women with a history of blood‑clotting disorders, uncontrolled hypertension, certain cancers, active liver disease, or known hypersensitivity to any component. It should also be avoided by smokers over 35 years of age and by anyone taking strong CYP3A4‑inducing medications without additional contraceptive protection.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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