Product image of Levitra (Vardenafil) supplied by GNH India

Levitra

Active Ingredient:
Vardenafil
Origin:
EU

Levitra (Vardenafil)

Vardenafil, the active ingredient in Levitra, is a phosphodiesterase type 5 (PDE5) inhibitor presented as a buccal formulation for buccal use. It treats erectile dysfunction in adult males.

GNH India supplies Levitra as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bayer Ag

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Indications & Clinical Uses

  • Levitra is a PDE5 inhibitor indicated for conditions affecting male sexual function.
  • Erectile dysfunction: improves the ability to achieve and maintain an erection sufficient for sexual activity when sexual stimulation occurs.

How It Works

  • Vardenafil selectively inhibits the phosphodiesterase type 5 enzyme in the corpus cavernosum, preventing the breakdown of cyclic guanosine monophosphate (cGMP). Elevated cGMP levels lead to smooth‑muscle relaxation, increased blood flow to the penile tissue, and facilitation of an erection in response to sexual stimulation.

Side Effects

Common Side Effects

  • Headache: mild to moderate pain often reported.
  • Flushing: warmth and redness of the face or upper body.
  • Nasal congestion: sensation of a blocked nose.
  • Dyspepsia: upset stomach or indigestion.
  • Back pain: transient muscular discomfort.
  • Visual changes: blurred vision or color tinge.

Serious or Rare Side Effects

  • Priapism: prolonged erection lasting more than four hours.
  • Sudden vision loss: abrupt loss of vision in one or both eyes.
  • Sudden hearing loss: rapid decrease or loss of hearing.
  • Severe hypotension: marked drop in blood pressure causing dizziness.
  • Allergic reactions: rash, itching, swelling, or anaphylaxis.

Precautions & Warnings

  • Before prescribing Levitra, clinicians should consider several safety factors.
  • Cardiovascular assessment: evaluate for recent myocardial infarction or unstable angina.
  • Nitrate therapy: avoid concurrent use with nitrates due to risk of severe hypotension.
  • Blood pressure monitoring: do not use in uncontrolled hypertension or hypotension.
  • Renal/hepatic impairment: assess organ function and adjust dose if needed.
  • Drug interactions: review all concomitant medications for potential interactions.
  • Store at ambient temperature: keep in original packaging, protect from moisture and heat.

Avoid Interactions

Levitra may interact with several medicines that affect its metabolism or hemodynamic effects.

Major Interactions (Avoid)

  • Nitrates (e.g., nitroglycerin): can cause dangerous blood‑pressure drops.
  • Guanylate cyclase stimulators (e.g., riociguat): additive vasodilatory effect.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): increase vardenafil exposure.

Moderate Interactions (Monitor Closely)

  • Alpha‑blockers (e.g., doxazosin): may cause additive hypotension.
  • Antihypertensives (e.g., beta‑blockers): monitor blood pressure.
  • CYP3A4 inducers (e.g., rifampin): may reduce efficacy.
  • Protease inhibitors (e.g., ritonavir): may increase plasma levels.

Frequently Asked Questions

Levitra contains the active ingredient vardenafil and is prescribed to treat erectile dysfunction in adult men. It helps improve the ability to achieve and maintain an erection sufficient for sexual activity when sexual stimulation occurs.

Vardenafil selectively blocks the phosphodiesterase type 5 enzyme in penile tissue, which prevents the breakdown of cyclic GMP. Higher cyclic GMP levels cause smooth‑muscle relaxation and increased blood flow to the corpus cavernosum, facilitating an erection in response to sexual stimulation.

The appropriate dose of Levitra is determined by a qualified prescriber based on the patient’s health status, concomitant medications, and response to therapy. Patients should follow the dosing instructions provided by their healthcare professional.

Levitra is indicated for use in adult males and is not recommended for women. There is no established safety data for use during pregnancy or lactation, and it should not be used by pregnant or breastfeeding women.

To request Levitra, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Levitra (vardenafil) belongs to the same PDE5 inhibitor class as sildenafil and tadalafil. While all three increase cyclic GMP to facilitate erections, they differ in onset of action, duration, and specific interaction profiles. Vardenafil typically has a rapid onset (30‑60 minutes) and a duration of about 4‑5 hours.

Levitra should be stored at ambient temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct heat, and store it out of reach of children.

Levitra is supplied as a buccal formulation. The tablet is placed against the inner cheek and allowed to dissolve, after which the patient may swallow any remaining residue. Administration should occur prior to anticipated sexual activity, as directed by a healthcare professional.

The most serious risks include priapism (a prolonged erection lasting more than four hours), sudden loss of vision, sudden loss of hearing, and severe hypotension, especially when combined with nitrates or other vasodilators. Patients should seek immediate medical attention if any of these events occur.

Levitra should not be used by individuals taking nitrates, those with severe cardiovascular disease such as recent myocardial infarction, uncontrolled hypertension or hypotension, patients with known hypersensitivity to vardenafil, or anyone for whom sexual activity is contraindicated.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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