Product image of Levmentin (Amoxicillin, Clavulanic Acid) supplied by GNH India

Levmentin

Active Ingredient:
Amoxicillin, Clavulanic Acid
Origin:
EU

Levmentin (Amoxicillin, Clavulanic Acid)

Amoxicillin and Clavulanic Acid, the active ingredient in Levmentin, is a penicillin/β‑lactamase inhibitor combination presented as an injectable solution for intravenous use. It treats bacterial infections such as respiratory, urinary, intra‑abdominal, and skin/soft‑tissue infections in adult patients.

GNH India supplies Levmentin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable cold‑chain logistics for injectable medicines. Clients benefit from on‑time delivery, regulatory support and comprehensive after‑sales service.

Manufacturer / TM Owner

Laboratoires Delbert

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Levmentin, a penicillin/β‑lactamase inhibitor combination, is employed to manage bacterial infections affecting various organ systems.

  • Respiratory tract infections: effective against common pathogens causing pneumonia, bronchitis and sinusitis.
  • Urinary tract infections: eradicates susceptible Gram‑negative and Gram‑positive bacteria causing cystitis and pyelonephritis.
  • Intra‑abdominal infections: provides coverage for mixed aerobic and anaerobic organisms in peritonitis and postoperative infections.
  • Skin and soft tissue infections: treats cellulitis, abscesses and wound infections caused by susceptible bacteria.

How It Works

  • Amoxicillin inhibits bacterial cell‑wall synthesis by binding to penicillin‑binding proteins, preventing peptidoglycan cross‑linking. Clavulanic acid, a β‑lactamase inhibitor, binds irreversibly to β‑lactamase enzymes produced by resistant bacteria, protecting amoxicillin from enzymatic degradation and extending its antimicrobial spectrum. The combined effect results in bactericidal activity against a broad range of Gram‑positive and Gram‑negative organisms, including Haemophilus influenzae, Streptococcus pneumoniae and many anaerobes.

Side Effects

Adverse reactions to Levmentin may vary in frequency and severity.

Common Side Effects

  • Diarrhea: mild to moderate watery stools.
  • Nausea: feeling of queasiness.
  • Rash: erythematous skin eruption.

Serious or Rare Side Effects

  • Anaphylaxis: severe, potentially life‑threatening allergic reaction.
  • Clostridioides difficile‑associated diarrhea: severe colitis.
  • Stevens‑Johnson syndrome: extensive skin detachment.

Precautions & Warnings

Before using Levmentin, consider the following precautions to ensure safe administration.

  • Renal impairment: dose may need adjustment and renal function should be monitored.
  • Hepatic dysfunction: monitor liver enzymes during therapy.
  • History of penicillin allergy: avoid use in patients with known hypersensitivity.
  • Concomitant anticoagulant therapy: monitor INR or PT for increased bleeding risk.
  • Use in pregnancy and lactation: only if benefits outweigh potential risks.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Levmentin can interact with other medicines; some require avoidance while others need close monitoring.

Major Interactions (Avoid)

  • Probenecid: reduces renal excretion of amoxicillin, increasing plasma levels.
  • Methotrexate: may enhance methotrexate toxicity.
  • Warfarin: potentiates anticoagulant effect, increasing bleeding risk.
  • Oral contraceptives: may reduce efficacy, leading to breakthrough bleeding.

Moderate Interactions (Monitor Closely)

  • Allopurinol: increased risk of skin rash.
  • Ciprofloxacin: possible antagonism reducing antibacterial activity.
  • Clarithromycin: may increase liver enzyme elevations.

Frequently Asked Questions

Levmentin is indicated for a range of bacterial infections, including community‑acquired and hospital‑acquired respiratory tract infections, urinary tract infections, intra‑abdominal infections such as peritonitis, and skin or soft‑tissue infections like cellulitis and abscesses. It is used when the causative organisms are susceptible to the amoxicillin‑clavulanic acid combination.

Amoxicillin disrupts bacterial cell‑wall synthesis by binding to penicillin‑binding proteins, leading to cell lysis. Clavulanic acid inhibits β‑lactamase enzymes that many resistant bacteria produce, protecting amoxicillin from degradation. This synergy broadens the antimicrobial spectrum to include β‑lactamase‑producing strains.

The exact dose of Levmentin is set by the prescribing clinician based on the type and severity of the infection, the patient’s age, weight, renal and hepatic function, and local antimicrobial guidelines. No fixed regimen is provided here; the prescriber tailors therapy to each individual case.

Safety data for Levmentin in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant. Clinicians should discuss the risk‑benefit profile with the patient and consider alternative agents when appropriate.

To order Levmentin, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain handling for injectables) and any required import documentation.

Plain amoxicillin lacks a β‑lactamase inhibitor, so it may be inactivated by bacteria that produce β‑lactamase enzymes. Levmentin adds clavulanic acid, which blocks those enzymes, extending coverage to resistant strains such as certain Haemophilus, Staphylococcus and anaerobic organisms. This makes Levmentin a broader‑spectrum option for mixed infections.

Levmentin should be stored at 2‑8 °C (refrigerated). Keep the vials in their original packaging, protect them from light, and avoid freezing or shaking the solution. Maintaining the cold chain preserves drug stability and potency.

Levmentin is supplied as an injectable solution for intravenous infusion. It is administered by a qualified healthcare professional under aseptic conditions, typically diluted in an appropriate IV fluid and infused over the period recommended by the prescriber, based on the infection being treated.

The most serious adverse events include severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, and rare but life‑threatening skin disorders like Stevens‑Johnson syndrome or toxic epidermal necrolysis. Prompt medical attention is required if any of these symptoms develop.

Levmentin is contraindicated in patients with a documented hypersensitivity to amoxicillin, clavulanic acid, or any other β‑lactam antibiotics. It should also be avoided in individuals who have previously experienced severe reactions such as anaphylaxis or Stevens‑Johnson syndrome related to β‑lactam therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.