Product image of Levobupivacaína Altan (Levobupivacaine) supplied by GNH India

Levobupivacaína Altan

Active Ingredient:
Levobupivacaine
Origin:
EU

Levobupivacaína Altan (Levobupivacaine)

Levobupivacaine, the active ingredient in Levobupivacaína Altan, is a local anesthetic presented for epidural use. It provides reversible nerve blockade for surgical anesthesia, labor analgesia, and postoperative pain management in adult patients, offering a stereoselective formulation with a prolonged duration and reduced cardiotoxicity compared with racemic bupivacaine.

GNH India supplies Levobupivacaína Altan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Altan Pharmaceuticals S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Levobupivacaine is a local anesthetic used in the epidural pathway to provide analgesia and anesthesia.

  • Surgical procedures: provides epidural anesthesia for intra‑operative pain control.
  • Labor: offers analgesia during childbirth.
  • Post‑operative care: manages pain after surgery.

How It Works

  • Levobupivacaine produces a reversible blockade of voltage‑gated sodium channels in neuronal membranes, preventing the initiation and propagation of nerve impulses. By stabilising the neuronal membrane, it inhibits depolarisation, resulting in loss of sensation in the targeted region while preserving motor function at lower concentrations.

Side Effects

Adverse reactions may occur after epidural administration of levobupivacaine.

Common Side Effects

  • Hypotension: transient drop in blood pressure.
  • Bradycardia: slowed heart rate.
  • Nausea: mild to moderate upset stomach.
  • Injection site pain: discomfort at the epidural site.

Serious or Rare Side Effects

  • Cardiac arrhythmia: irregular heart rhythm that may be life‑threatening.
  • Seizures: central nervous system excitation.
  • Respiratory depression: reduced breathing effort.
  • Systemic toxicity: signs of central or cardiovascular toxicity such as tinnitus, metallic taste, or loss of consciousness.

Precautions & Warnings

When using levobupivacaine, clinicians should observe specific safety measures.

  • Cardiovascular monitoring: continuously assess heart rate and blood pressure during epidural infusion.
  • Dose adjustment: avoid high concentrations in patients with pre‑existing cardiac disease.
  • Allergy assessment: screen for hypersensitivity to amide‑type local anesthetics.
  • Concurrent CNS depressants: use caution when combined with other agents that depress respiration.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Levobupivacaine may interact with other drugs, requiring careful management.

Major Interactions (Avoid)

  • Class I antiarrhythmic agents (e.g., quinidine): increase risk of cardiotoxicity.
  • Other local anesthetics: additive toxicity when administered together.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may enhance bradycardia.
  • General anesthetics (e.g., propofol): may potentiate central nervous system depression.
  • Opioids: may increase risk of respiratory depression.

Frequently Asked Questions

Levobupivacaína Altan contains levobupivacaine, which is used to provide epidural anesthesia for surgical procedures, to deliver analgesia during labor, and to manage postoperative pain. The drug works by blocking nerve signals in the area where it is administered, offering a long‑lasting, controllable block.

Levobupivacaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the initiation and propagation of action potentials. This reversible inhibition stops nerve impulse transmission, resulting in loss of sensation in the targeted region while preserving motor function at appropriate concentrations.

The specific dose and concentration are determined by the prescribing clinician based on the patient’s age, weight, procedure type, and clinical setting. Levobupivacaína Altan is supplied for use by qualified health‑care professionals who calculate the appropriate regimen for each individual case.

Safety data for levobupivacaine in pregnancy and lactation are limited. Use is generally reserved for situations where the benefit outweighs potential risk, such as obstetric analgesia under specialist supervision. Breastfeeding mothers should consult their obstetrician or anesthesiologist before exposure.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials. The sales team then replies with pricing, availability, shipping details (including cold‑chain if required) and import documentation.

Levobupivacaine is the S‑enantiomer of bupivacaine, offering a similar duration of action with a lower risk of cardiotoxicity and central nervous system toxicity. Both are amide‑type local anesthetics used epidurally, but levobupivacaine’s stereoselective profile makes it a preferred option when safety margins are a priority.

Levobupivacaína Altan should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight, and extreme temperature fluctuations. Ensure the container is sealed tightly to maintain sterility until use.

The drug is administered by a qualified health‑care professional via the epidural route. After aseptic preparation, the solution is injected into the epidural space using a catheter or needle, allowing controlled spread of the anesthetic to achieve the desired sensory block.

Serious risks include cardiovascular toxicity such as arrhythmias, severe hypotension, and central nervous system effects like seizures or respiratory depression. Systemic toxicity can occur if the drug enters the bloodstream in excessive amounts, requiring immediate medical intervention.

Patients with known hypersensitivity to amide‑type local anesthetics, those with severe cardiac conduction disorders, or individuals with uncontrolled epilepsy should avoid levobupivacaine. It is also contraindicated in patients where epidural placement is unsafe, such as those with infection at the injection site or coagulopathy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.