Product image of Levobupivakain Kabi (Levobupivacaine Hydrochloride) supplied by GNH India

Levobupivakain Kabi

Active Ingredient:
Levobupivacaine Hydrochloride
Origin:
EU

Levobupivakain Kabi (Levobupivacaine Hydrochloride)

Levobupivacaine Hydrochloride, the active ingredient in Levobupivakain Kabi, is a local anesthetic (amide) presented as a sterile solution for epidural, infiltration, intrathecal and peripheral administration. It provides reversible nerve block for surgical anesthesia, labor analgesia and postoperative pain management.
GNH India supplies Levobupivakain Kabi as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Fresenius Kabi D.O.O.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Levobupivakain Kabi, a local anesthetic, provides nerve block for various surgical and obstetric procedures.
  • Surgical anesthesia: delivers dense sensory block to facilitate operative procedures.
  • Labor analgesia: offers effective pain relief during childbirth.
  • Postoperative pain management: reduces pain intensity after surgery.

How It Works

  • Levobupivacaine hydrochloride reversibly blocks voltage‑gated sodium channels on neuronal membranes, inhibiting the initiation and propagation of action potentials. This prevents nerve impulse transmission, resulting in loss of sensation in the targeted area without affecting consciousness.

Side Effects

Adverse reactions may occur following administration of Levobupivakain Kabi.

Common Side Effects

  • Hypotension: transient drop in blood pressure.
  • Bradycardia: slowed heart rate.
  • Nausea: feeling of sickness.
  • Dizziness: light‑headed sensation.
  • Metallic taste: transient taste alteration.
  • Injection site pain: discomfort at the injection site.

Serious or Rare Side Effects

  • Cardiac arrhythmia: irregular heart rhythm.
  • Seizures: uncontrolled electrical activity in the brain.
  • Methemoglobinemia: abnormal hemoglobin levels.
  • Allergic reactions: rash, itching, or anaphylaxis.
  • Central nervous system toxicity: confusion or loss of consciousness.
  • Persistent nerve block: prolonged loss of sensation.

Precautions & Warnings

  • When using Levobupivakain Kabi, consider the following safety measures.
  • Patient assessment: evaluate cardiovascular and hepatic status before administration.
  • Dose adjustment in hepatic impairment: reduce dose if liver function is compromised.
  • Avoid in known hypersensitivity: do not administer to patients with documented allergy to amide local anesthetics.
  • Monitor cardiovascular status: observe blood pressure and heart rate during and after injection.
  • Use with caution in pregnancy: safety data are limited; weigh benefits against potential risks.
  • Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Levobupivakain Kabi may interact with other medicines; awareness helps prevent adverse events.

Major Interactions (Avoid)

  • Other local anesthetics: increased risk of cumulative toxicity.
  • CYP3A4 inhibitors: may raise plasma concentrations of levobupivacaine.
  • Class I antiarrhythmics: can enhance cardiotoxic effects.

Moderate Interactions (Monitor Closely)

  • Epinephrine: may prolong block duration.
  • Diuretics: can alter protein binding and free drug levels.
  • Beta‑blockers: may mask tachycardia signs of toxicity.

Frequently Asked Questions

Levobupivakain Kabi is a sterile solution of levobupivacaine hydrochloride used as a local anesthetic for surgical anesthesia, labor analgesia, and postoperative pain management. It provides reversible nerve block when administered via epidural, infiltration, intrathecal, or peripheral routes.

Levobupivacaine blocks voltage‑gated sodium channels on neuronal membranes, preventing the initiation and propagation of action potentials. This inhibition stops nerve impulse transmission, resulting in loss of sensation in the area where the drug is applied.

The dose of Levobupivakain Kabi is determined by the prescribing clinician based on the type of procedure, patient characteristics, and route of administration. Healthcare professionals adjust the amount to achieve the desired anesthetic effect while maintaining safety.

Safety data for levobupivacaine during pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. Use only if the potential benefit justifies any potential risk to the fetus or infant, and follow local regulatory guidance.

To order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Levobupivakain Kabi contains levobupivacaine, the S‑enantiomer of bupivacaine, offering a similar duration of anesthesia with a lower risk of cardiotoxicity and central nervous system toxicity. Clinicians may prefer it when a safer profile is desired for high‑risk patients.

Store the product at controlled room temperature, below 25 °C, in its original packaging. Protect it from moisture, direct sunlight, and extreme temperatures. Do not freeze. Inspect the solution for particulate matter or discoloration before use.

Levobupivakain Kabi is administered by a qualified healthcare professional via epidural, infiltration, intrathecal, or peripheral injection. The specific technique and volume depend on the clinical indication and patient factors, and it should be performed under appropriate monitoring.

Serious risks include cardiac arrhythmias, seizures, severe hypotension, methemoglobinemia, and allergic reactions such as anaphylaxis. Prompt recognition and supportive management are essential if any of these events occur during or after administration.

Patients with known hypersensitivity to levobupivacaine or other amide‑type local anesthetics, those with severe cardiac conduction disorders, or individuals with uncontrolled epilepsy should avoid this medication. Clinical judgment is required for patients with significant hepatic impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.