Product image of Levocarnitine Uni-Pharma (Levocarnitine) supplied by GNH India

Levocarnitine Uni-Pharma

Active Ingredient:
Levocarnitine
Origin:
EU

Levocarnitine Uni-Pharma (Levocarnitine)

Levocarnitine, the active ingredient in Levocarnitine Uni-Pharma, is an L‑carnitine nutritional supplement presented as an oral tablet for oral use. It is employed to treat primary and secondary carnitine deficiency and to support metabolic disorders by facilitating fatty‑acid transport into mitochondria, thereby aiding energy production.

GNH India supplies Levocarnitine Uni-Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics, ensuring product integrity from manufacturing sites in the European Union to end‑users across global markets.

Manufacturer / TM Owner

Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.

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Indications & Clinical Uses

Levocarnitine is used to address disorders of carnitine metabolism and related metabolic conditions.

  • Primary carnitine deficiency: restores intracellular carnitine levels and improves fatty‑acid oxidation.
  • Secondary carnitine deficiency: compensates for loss of carnitine due to renal disease, dialysis or certain medications.
  • Support of metabolic disorders: aids energy production in patients with fatty‑acid oxidation defects or mitochondrial dysfunction.

How It Works

  • Levocarnitine acts as a carrier molecule that transports long‑chain fatty acids across the inner mitochondrial membrane. By forming acyl‑carnitine esters, it enables β‑oxidation of fatty acids, generating acetyl‑CoA for the citric acid cycle and ATP synthesis. The increased availability of carnitine also facilitates removal of excess acyl groups, supporting overall cellular energy metabolism. Additionally, it helps maintain the balance of CoA pools within mitochondria, which is essential for various metabolic pathways.

Side Effects

Levocarnitine is generally well tolerated, but some users may experience adverse reactions.

Common Side Effects

  • Nausea: mild stomach upset.
  • Vomiting: occasional emesis.
  • Diarrhea: loose stools.
  • Abdominal discomfort: cramping or pain.
  • Headache: transient head pain.
  • Fish‑like body odor: odor of sweat or urine.

Serious or Rare Side Effects

  • Allergic reactions: rash, pruritus, or urticaria.
  • Anaphylaxis: severe, potentially life‑threatening hypersensitivity.
  • Severe hypotension: sudden drop in blood pressure.
  • Elevated liver enzymes: signs of hepatic stress.
  • Metabolic acidosis: abnormal blood pH.
  • Muscle weakness: unexplained loss of strength.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Renal impairment: monitor kidney function and adjust therapy as needed.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Concomitant medications: review for potential interactions.
  • Long‑term therapy: periodically assess plasma carnitine concentrations.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Levocarnitine may interact with other medicines; awareness of the interaction level is important.

Major Interactions (Avoid)

  • Valproic acid: may deplete carnitine stores, reducing efficacy.
  • Cisplatin: increased risk of nephrotoxicity when combined.
  • Phenobarbital: accelerates carnitine metabolism, lowering plasma levels.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible alteration of INR, monitor coagulation.
  • Insulin: carnitine may affect glucose utilization, adjust dose as needed.
  • Thyroid hormones: may modify metabolic response, observe thyroid function.

Frequently Asked Questions

Levocarnitine Uni-Pharma is an oral L‑carnitine nutritional supplement indicated for primary carnitine deficiency, secondary carnitine deficiency that can arise from renal loss or certain drugs, and for general metabolic support in conditions where fatty‑acid oxidation is impaired.

Levocarnitine functions as a carrier that shuttles long‑chain fatty acids into mitochondria. Inside the organelle it forms acyl‑carnitine esters, allowing β‑oxidation to proceed, which generates acetyl‑CoA for the citric acid cycle and ATP production, thereby supporting cellular energy metabolism.

The appropriate dose of Levocarnitine Uni-Pharma is determined by a qualified prescriber based on the individual’s clinical condition, age, weight, and laboratory findings. Patients should follow the dosing instructions provided on the prescription label and discuss any adjustments with their healthcare professional.

Safety data for levocarnitine in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before starting the product to weigh potential benefits against any uncertain risks.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Levocarnitine Uni-Pharma is an EU‑sourced, GMP‑manufactured oral tablet that meets strict quality standards. Compared with generic bulk powders or liquid formulations, the tablet offers precise dosing, convenient administration, and stable shelf‑life, while providing the same active ingredient and mechanism of action as other L‑carnitine products.

Store the tablets at room temperature, preferably below 25 °C, in the original container to protect them from moisture and direct sunlight. Keep the product out of reach of children and avoid exposing it to extreme temperatures or humidity, which could affect potency.

Levocarnitine Uni-Pharma is taken orally with a glass of water. The tablet should be swallowed whole unless the prescriber advises otherwise. It can be taken with or without food, but consistency with meals may help reduce occasional gastrointestinal discomfort.

The most serious adverse reactions include severe allergic responses such as rash, urticaria, or anaphylaxis, as well as rare cases of hypotension, elevated liver enzymes, metabolic acidosis, and marked muscle weakness. Patients experiencing any of these symptoms should seek immediate medical attention.

Individuals with a known hypersensitivity to levocarnitine or any excipients in the tablet should avoid the product. Patients with severe renal impairment should use it only under close medical supervision, as reduced clearance may increase the risk of adverse effects.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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