Product image of Levocetirizin Beta (Levocetirizine Dihydrochloride) supplied by GNH India

Levocetirizin Beta

Active Ingredient:
Levocetirizine Dihydrochloride
Origin:
EU

Levocetirizin Beta (Levocetirizine Dihydrochloride)

Levocetirizine Dihydrochloride, the active ingredient in Levocetirizin Beta, is a second‑generation H1 receptor antagonist presented as an oral tablet for oral use. It is employed to relieve symptoms of allergic rhinitis and chronic idiopathic urticaria in adults and children when appropriate.

GNH India supplies Levocetirizin Beta as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Betapharm Arzneimittel Gmbh

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Indications & Clinical Uses

Levocetirizine Dihydrochloride is used to manage allergic conditions by blocking peripheral H1 receptors.

  • Allergic rhinitis: reduces nasal congestion, sneezing, itching and watery discharge.
  • Seasonal allergic rhinitis: alleviates symptoms triggered by pollen or other seasonal allergens.
  • Chronic idiopathic urticaria: diminishes the frequency and severity of hives and associated itching.

How It Works

  • Levocetirizine Dihydrochloride selectively antagonizes peripheral H1 histamine receptors, preventing histamine from binding and activating the receptor cascade. By inhibiting this pathway, it reduces vascular permeability, sensory nerve stimulation, and smooth‑muscle contraction, thereby mitigating the classic signs of an allergic response without significant central nervous system penetration.

Side Effects

Levocetirizin Beta is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Drowsiness: mild to moderate sleepiness, especially after the first dose.
  • Fatigue: a feeling of reduced energy or tiredness.
  • Dry mouth: decreased salivation leading to oral dryness.
  • Headache: mild to moderate cranial pain.
  • Nausea: occasional stomach upset.
  • Dizziness: transient light‑headedness.

Serious or Rare Side Effects

  • Angioedema: swelling of face, lips, tongue or throat.
  • Anaphylaxis: severe, life‑threatening allergic reaction.
  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Hepatic enzyme elevation: abnormal liver function tests.
  • Cardiac arrhythmia: rare QT‑interval prolongation.

Precautions & Warnings

Before initiating therapy, consider patient‑specific factors and safety measures.

  • Renal function assessment: dose adjustment may be required in renal impairment.
  • Hepatic impairment: use with caution in patients with liver disease.
  • Sedation risk: avoid operating machinery or driving until individual response is known.
  • Hypersensitivity monitoring: discontinue if signs of allergic reaction appear.
  • Pregnancy and lactation: only use if benefits outweigh potential risks.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Levocetirizin Beta may interact with other medicines that affect its metabolism or enhance sedation.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may increase levocetirizine plasma levels.
  • Concurrent sedating antihistamines: additive drowsiness.
  • Alcohol: potentiates central nervous system depression.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampin): may reduce efficacy.
  • Theophylline: possible increase in theophylline concentrations.
  • Certain antidepressants (e.g., fluoxetine): may modestly raise levocetirizine exposure.

Frequently Asked Questions

Levocetirizin Beta contains levocetirizine dihydrochloride, which is indicated for the symptomatic relief of allergic rhinitis—including seasonal forms—and for the treatment of chronic idiopathic urticaria, helping to reduce nasal symptoms, sneezing, itching and the occurrence of hives.

Levocetirizine acts as a selective peripheral H1‑receptor antagonist. By blocking histamine from binding to these receptors, it prevents the cascade that leads to vasodilation, increased vascular permeability, and nerve stimulation, thereby reducing the classic signs of an allergic response without significant sedation.

The appropriate dose of Levocetirizin Beta is determined by the prescribing healthcare professional based on the patient’s age, clinical condition, renal function and other factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for levocetirizine in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made in consultation with a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Levocetirizin Beta is a second‑generation antihistamine, offering effective H1‑receptor blockade with a lower incidence of sedation compared with first‑generation agents such as diphenhydramine. Its rapid onset and once‑daily dosing make it convenient, while maintaining a safety profile comparable to other modern antihistamines like cetirizine or fexofenadine.

Levocetirizin Beta should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Keeping the product in a dry, cool environment helps maintain its potency throughout the shelf life.

Levocetirizin Beta is taken orally, usually as a tablet, with or without food. The tablet should be swallowed whole with a glass of water. Patients should follow the dosing schedule prescribed by their healthcare professional.

Serious but rare adverse events include angioedema, anaphylactic reactions, severe skin eruptions such as Stevens‑Johnson syndrome, significant liver enzyme elevations, and, in very uncommon cases, cardiac arrhythmias like QT‑interval prolongation. Any signs of these conditions require immediate medical attention.

Levocetirizin Beta is contraindicated in individuals with known hypersensitivity to levocetirizine, other piperazine antihistamines, or any of the product’s excipients. Caution is also advised for patients with severe renal impairment, as dose adjustment may be necessary, and it should be avoided in those with a history of serious allergic reactions to antihistamines.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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