Product image of Levocetirizin Bluefish (Levocetirizine Dihydrochloride) supplied by GNH India

Levocetirizin Bluefish

Active Ingredient:
Levocetirizine Dihydrochloride
Origin:
EU

Levocetirizin Bluefish (Levocetirizine Dihydrochloride)

Levocetirizine Dihydrochloride, the active ingredient in Levocetirizin Bluefish, is an antihistamine presented as an oral tablet for oral use. It relieves symptoms of allergic rhinitis, chronic urticaria and other IgE‑mediated allergic conditions in adults and children as directed by a prescriber.

GNH India supplies Levocetirizin Bluefish as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bluefish Pharmaceuticals Ab

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Indications & Clinical Uses

Levocetirizine is an antihistamine that acts on the histamine H1‑receptor pathway to control allergic disease.

  • Allergic rhinitis: reduces nasal congestion, sneezing and itching.
  • Chronic idiopathic urticaria: diminishes hives and associated pruritus.
  • Seasonal allergic conjunctivitis: alleviates eye itching and redness.

How It Works

  • Levocetirizine Dihydrochloride selectively blocks peripheral H1‑histamine receptors, preventing histamine‑induced vasodilation, increased vascular permeability, and sensory nerve stimulation. By inhibiting this receptor binding, the drug reduces the early‑phase allergic response without significant anticholinergic activity, leading to relief of nasal, cutaneous and ocular symptoms.

Side Effects

Adverse reactions may occur with any antihistamine therapy. Most are mild and reversible.

Common Side Effects

  • Drowsiness: mild to moderate sedation, especially after the first dose.
  • Headache: transient, usually resolves without intervention.
  • Dry mouth: decreased salivation, can be managed with hydration.
  • Fatigue: general tiredness that improves with continued use.
  • Nausea: mild gastrointestinal upset.

Serious or Rare Side Effects

  • Angioedema: swelling of face, lips or throat requiring urgent care.
  • Anaphylaxis: severe allergic reaction with respiratory compromise.
  • Stevens‑Johnson syndrome: rare severe skin eruption.
  • Hepatic dysfunction: abnormal liver enzymes in isolated cases.
  • Cardiac arrhythmia: rare reports of QT prolongation.

Precautions & Warnings

Before initiating therapy, consider patient‑specific factors and safety measures.

  • Renal function: assess in severe impairment; dose may need adjustment.
  • Sedation: avoid operating machinery until individual response is known.
  • Alcohol: limit intake as combined effect may increase drowsiness.
  • Pediatric use: not recommended for children under six years without specialist advice.
  • Hypersensitivity: discontinue if rash, swelling or breathing difficulty develop.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Levocetirizine may interact with other medicines that influence sedation or hepatic metabolism.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole): can raise levocetirizine plasma levels.
  • Alcohol: additive central nervous system depression.
  • Other H1‑antihistamines: may cause excessive sedation.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampicin): may reduce therapeutic effect.
  • Theophylline: levocetirizine can increase theophylline concentrations.
  • CNS depressants (e.g., benzodiazepines): may enhance drowsiness.
  • Anticholinergic agents: may worsen dry mouth.

Frequently Asked Questions

Levocetirizin Bluefish contains levocetirizine dihydrochloride, an H1‑antihistamine indicated for relief of symptoms associated with allergic rhinitis, chronic idiopathic urticaria and seasonal allergic conjunctivitis. It helps reduce nasal congestion, sneezing, itching, hives and eye irritation when prescribed by a qualified healthcare professional.

Levocetirizine selectively blocks peripheral H1‑histamine receptors, preventing histamine from binding and triggering the cascade that leads to vasodilation, increased capillary permeability and nerve stimulation. By inhibiting this pathway, the drug diminishes the early‑phase allergic response, providing symptom relief without significant anticholinergic effects.

The dosage of Levocetirizin Bluefish is determined by the prescribing clinician based on the patient’s age, renal function and the severity of the allergic condition. Typical adult regimens range from 5 mg once daily, but the exact amount and frequency must be set by a qualified prescriber.

Safety data in pregnancy are limited; levocetirizine should only be used if the potential benefit justifies any potential risk to the fetus. It is excreted in breast milk in small amounts, so breastfeeding mothers should discuss risks and benefits with their healthcare provider before continuing therapy.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Levocetirizin is the active R‑enantiomer of cetirizine, offering similar efficacy with a slightly lower incidence of sedation for many patients. Compared with first‑generation antihistamines, it provides better selectivity for H1 receptors and fewer anticholinergic side effects, making it a preferred option for chronic allergic conditions.

Levocetirizin Bluefish should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in bathrooms or other humid environments.

The medication is supplied as an oral tablet that is swallowed whole with a glass of water. It can be taken with or without food, but patients should follow the specific instructions provided by their prescriber regarding timing and any food‑related considerations.

While generally well tolerated, serious adverse events can include angioedema, anaphylactic reactions, severe skin disorders such as Stevens‑Johnson syndrome, and rare cardiac arrhythmias. Patients should seek immediate medical attention if they experience swelling of the face or throat, rash, or any signs of cardiac disturbance.

Levocetirizin Bluefish is contraindicated in individuals with known hypersensitivity to levocetirizine, cetirizine or any other component of the formulation. Caution is also advised for patients with severe renal impairment, and it should not be used in children under six years of age unless specifically prescribed by a specialist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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