Product image of Levocetirizin Dr.Max (Levocetirizine Dihydrochloride) supplied by GNH India

Levocetirizin Dr.Max

Active Ingredient:
Levocetirizine Dihydrochloride
Origin:
EU

Levocetirizin Dr.Max (Levocetirizine Dihydrochloride)

Levocetirine, the active ingredient in Levocetirizin Dr.Max, is a second‑generation antihistamine presented as an oral dosage form for oral use. It is indicated for the relief of nasal congestion, sneezing, itching and watery eyes associated with allergic rhinitis, and for reducing hives and itching in chronic idiopathic urticaria in adults and children.

GNH India supplies Levocetirizin Dr.Max as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved products to global healthcare providers.

Manufacturer / TM Owner

Dr. Max Pharma S.R.O.

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Indications & Clinical Uses

Levocetirizine is a second‑generation antihistamine that acts on histamine‑mediated allergic pathways.

  • Allergic rhinitis: alleviates nasal congestion, sneezing, itching and watery eyes.
  • Chronic idiopathic urticaria: reduces frequency and severity of hives and itching.
  • Seasonal allergic rhinitis: provides symptom control during pollen exposure.

How It Works

  • Levocetirizine selectively blocks peripheral H1‑histamine receptors, preventing histamine from binding and activating the cascade that leads to vasodilation, increased vascular permeability, and sensory nerve stimulation. By inhibiting this receptor, the drug reduces the classic signs of allergic inflammation without readily crossing the blood‑brain barrier, limiting central sedation.

Side Effects

Levocetirizine may cause a range of adverse reactions, which are generally classified by frequency.

Common Side Effects

  • Drowsiness: mild to moderate sedation, especially at the start of therapy.
  • Headache: transient, often resolves without intervention.
  • Dry mouth: reduced salivation leading to mild oral discomfort.

Serious or Rare Side Effects

  • Anaphylaxis: acute, potentially life‑threatening allergic reaction requiring immediate medical attention.
  • Stevens‑Johnson syndrome: severe skin eruption with mucosal involvement, rare but serious.
  • Cardiac arrhythmia: rare reports of QT prolongation or other rhythm disturbances.

Precautions & Warnings

Before prescribing Levocetirizine, clinicians should consider several safety aspects.

  • Renal function: adjust dose in patients with severe renal impairment.
  • Hepatic function: use with caution in moderate liver disease.
  • Sedation: advise patients not to operate machinery if drowsy.
  • Pediatric use: not recommended for children under 6 years of age.
  • Hypersensitivity: discontinue if signs of allergic reaction appear.
  • Store at room temperature: keep in original packaging, protect from moisture.

Avoid Interactions

Levocetirizine can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Ritonavir: may increase levocetirizine plasma concentrations.
  • Theophylline: concurrent use can raise the risk of theophylline toxicity.
  • Alcohol: combined use may enhance central nervous system depression.

Moderate Interactions (Monitor Closely)

  • CNS depressants (e.g., benzodiazepines): additive sedation.
  • Anticholinergic agents: may increase dry mouth.
  • CYP3A4 inhibitors (e.g., ketoconazole): may modestly raise levocetirizine levels.

Frequently Asked Questions

Levocetirizin Dr.Max contains levocetirizine, a second‑generation antihistamine indicated for the relief of symptoms associated with allergic rhinitis, such as sneezing, nasal congestion and itchy eyes, as well as for managing chronic idiopathic urticaria (hives) in adults and children.

Levocetirizine works by selectively blocking peripheral H1‑histamine receptors. This inhibition prevents histamine‑induced vasodilation, increased vascular permeability, and sensory nerve activation, thereby reducing the typical signs of an allergic response without significant central nervous system penetration.

The prescribed dose of Levocetirizin Dr.Max is determined by the treating clinician based on the patient’s age, renal function and severity of symptoms. In most adult cases, a single daily dose is typical, but the exact amount should follow the prescriber’s instructions.

Levocetirizine is classified as Pregnancy Category B, indicating that animal studies have not shown risk to the fetus and there are no adequate human studies. It is generally considered low risk, but pregnant or nursing women should consult their healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Levocetirizine is the active enantiomer of cetirizine, offering similar antihistaminic efficacy with a slightly lower incidence of sedation in many patients. Both belong to the second‑generation H1‑antagonist class, but levocetirizine may provide more consistent plasma concentrations and a faster onset of action.

Store Levocetirizin Dr.Max at room temperature, below 25 °C. Keep the tablets in the original blister pack or container, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Levocetirizin Dr.Max is administered orally, typically as a whole tablet swallowed with water. It may be taken with or without food, and patients should follow the dosing schedule prescribed by their healthcare professional.

Although rare, serious adverse reactions can include anaphylaxis, severe skin reactions such as Stevens‑Johnson syndrome, and cardiac arrhythmias. Patients should seek immediate medical attention if they experience symptoms like difficulty breathing, widespread rash, or irregular heartbeats.

Levocetirizin Dr.Max should be avoided in individuals with known hypersensitivity to levocetirizine or any excipients in the formulation. It is also not recommended for children younger than six years of age and should be used with caution in patients with severe renal impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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