Product image of Levocetirizin Genericon (Levocetirizine Dihydrochloride) supplied by GNH India

Levocetirizin Genericon

Active Ingredient:
Levocetirizine Dihydrochloride
Origin:
EU

Levocetirizin Genericon (Levocetirizine Dihydrochloride)

Levocetirizine, the active ingredient in Levocetirizin Genericon, is a second‑generation antihistamine presented as a tablet for oral use. It is used to treat allergic rhinitis and chronic idiopathic urticaria in adults and children when appropriate.
GNH India supplies Levocetirizin Genericon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Genericon Pharma Gesellschaft M.B.H.

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Indications & Clinical Uses

Levocetirizin Genericon is a second‑generation H1‑antihistamine that acts on allergic and urticarial pathways.

  • Allergic rhinitis (seasonal or perennial): reduces sneezing, nasal itching, rhinorrhea and congestion.
  • Chronic idiopathic urticaria: alleviates hives and associated itching.
  • Allergic conjunctivitis: relieves eye itching, redness and tearing.

How It Works

  • Levocetirizine dihydrochloride selectively blocks peripheral H1‑histamine receptors, preventing histamine from binding and triggering the cascade that leads to vasodilation, increased vascular permeability, and sensory nerve activation. By inhibiting this receptor‑mediated response, the drug reduces the typical signs and symptoms of allergic inflammation without significant central nervous system penetration.

Side Effects

Levocetirizin Genericon may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Drowsiness or fatigue: may affect alertness.
  • Dry mouth: sensation of oral dryness.
  • Nausea: occasional stomach upset.
  • Taste alteration: metallic or altered taste perception.
  • Nasal congestion: transient blockage.

Serious or Rare Side Effects

  • Angioedema: swelling of face, lips or tongue.
  • Anaphylaxis: severe, life‑threatening allergic reaction.
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis: severe skin eruptions.
  • Tachycardia: rapid heart rate.
  • Hepatic enzyme elevation: abnormal liver function tests.
  • Blood dyscrasias: rare blood cell abnormalities.

Precautions & Warnings

When prescribing Levocetirizin Genericon, clinicians should consider several safety aspects.

  • Renal impairment: use with caution and monitor renal function.
  • Hepatic impairment: consider dose adjustment if liver disease is present.
  • Elderly patients: increased sensitivity to sedation; monitor for drowsiness.
  • Pregnancy and breastfeeding: discuss potential risks with a healthcare professional.
  • Driving or operating machinery: may cause drowsiness; advise patients to avoid hazardous tasks until they know how the drug affects them.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Levocetirizin Genericon can interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Ketoconazole or other strong CYP3A4 inhibitors: may increase levocetirizine plasma concentrations.
  • Erythromycin: can raise drug levels, enhancing side effects.
  • Theophylline: levocetirizine may increase theophylline concentrations, risking toxicity.

Moderate Interactions (Monitor Closely)

  • Alcohol: additive central nervous system depression, increasing drowsiness.
  • Benzodiazepines or other CNS depressants: may enhance sedative effects.
  • Anticholinergic agents: combined use can worsen dry mouth.
  • Other antihistamines: risk of cumulative antihistaminic effects.
  • Rifampicin: may reduce levocetirizine exposure, decreasing efficacy.

Frequently Asked Questions

Levocetirizin Genericon contains levocetirizine, a second‑generation antihistamine indicated for the relief of symptoms associated with allergic rhinitis and chronic idiopathic urticaria. It helps reduce sneezing, nasal congestion, itching, and hives in patients who require an oral, non‑sedating antihistamine.

Levocetirizine works by selectively blocking peripheral H1‑histamine receptors. By preventing histamine from binding to these receptors, it stops the cascade that leads to vasodilation, increased vascular permeability, and nerve stimulation, thereby reducing the classic signs of an allergic response such as itching, swelling, and mucus production.

The appropriate dose of Levocetirizin Genericon is determined by the prescribing healthcare professional based on the patient’s age, clinical condition, and renal function. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

Safety data for levocetirizine in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Levocetirizin Genericon.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Levocetirizin Genericon is a second‑generation antihistamine, offering effective allergy relief with a lower incidence of sedation compared with first‑generation agents such as diphenhydramine. Its rapid onset and once‑daily dosing make it convenient, while its selectivity for peripheral H1 receptors reduces central nervous system effects.

Store Levocetirizin Genericon tablets at ambient temperature, below 25 °C. Keep the product in its original blister or container, protect it from moisture and direct sunlight, and ensure the packaging remains tightly closed until use.

Levocetirizin Genericon is taken orally, usually with or without food, as directed by a healthcare professional. The tablet should be swallowed whole with a glass of water and not crushed or chewed unless specifically instructed.

Serious but rare risks include angioedema, anaphylactic reactions, severe skin disorders such as Stevens‑Johnson syndrome, and significant hepatic enzyme elevations. Patients should seek immediate medical attention if they experience swelling of the face or throat, rash, or signs of liver dysfunction.

Levocetirizin Genericon should be avoided in individuals with known hypersensitivity to levocetirizine or any excipients in the formulation. Caution is advised for patients with severe renal impairment, and it should be used only under medical supervision in pregnant or breastfeeding women.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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