Product image of Levocetirizin Hexal (Levocetirizine Dihydrochloride) supplied by GNH India

Levocetirizin Hexal

Active Ingredient:
Levocetirizine Dihydrochloride
Origin:
EU

Levocetirizin Hexal (Levocetirizine Dihydrochloride)

Levocetirizine Dihydrochloride, the active ingredient in Levocetirizin Hexal, is an antihistamine presented as an oral dosage form for oral use. It is used to relieve symptoms of allergic rhinitis and chronic idiopathic urticaria in adults and children.
GNH India supplies Levocetirizin Hexal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Hexal Pharma Gmbh

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Indications & Clinical Uses

Levocetirizin Hexal is an H1‑antihistamine that acts on allergic and urticarial conditions.

  • Allergic rhinitis: reduces nasal congestion, itching, sneezing and watery discharge.
  • Chronic idiopathic urticaria: alleviates wheals and itching associated with persistent hives.

How It Works

  • Levocetirizine Dihydrochloride selectively blocks peripheral H1 histamine receptors, preventing histamine from binding and triggering the cascade that leads to vasodilation, increased vascular permeability, and sensory nerve stimulation. By inhibiting this pathway, it reduces the classic signs of allergic inflammation without significant central nervous system penetration.

Side Effects

Levocetirizin Hexal may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Drowsiness: mild sleepiness that may affect alertness.
  • Headache: occasional tension‑type headache.
  • Dry mouth: reduced salivation.
  • Fatigue: general feeling of tiredness.
  • Nausea: mild stomach upset.
  • Dizziness: brief episodes of light‑headedness.

Serious or Rare Side Effects

  • Angioedema: swelling of face, lips or throat.
  • Severe skin reactions: such as Stevens‑Johnson syndrome.
  • Anaphylaxis: rare systemic allergic response.
  • Thrombocytopenia: low platelet count.
  • Hepatic injury: abnormal liver function tests.
  • Cardiac arrhythmia: irregular heart rhythm.

Precautions & Warnings

Before using Levocetirizin Hexal, consider the following safety points.

  • Pregnancy: consult a healthcare professional before use.
  • Renal impairment: dose may need adjustment in reduced kidney function.
  • Elderly patients: monitor for increased sedation.
  • Driving or operating machinery: caution due to possible drowsiness.
  • Concomitant medications: review all drugs for potential interactions.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Levocetirizin Hexal can interact with several medicines; awareness helps avoid adverse outcomes.

Major Interactions (Avoid)

  • Alcohol: may intensify sedation and impair coordination.
  • Central nervous system depressants: additive drowsiness risk.

Moderate Interactions (Monitor Closely)

  • Ketoconazole: may increase levocetirizine plasma concentrations.
  • Ritonavir: can raise drug levels, requiring observation.
  • Theophylline: may experience elevated theophylline levels.
  • Other antihistamines: combined use can enhance antihistaminic effects.

Frequently Asked Questions

Levocetirizin Hexal is indicated for the relief of symptoms associated with allergic rhinitis, such as sneezing, itching and nasal discharge, and for the treatment of chronic idiopathic urticaria, helping to reduce hives and itching.

Levocetirizine selectively blocks peripheral H1 histamine receptors, preventing histamine from binding and triggering the inflammatory cascade that causes the typical signs of allergy, thereby reducing nasal congestion, itching and skin wheals.

The appropriate dose of Levocetirizin Hexal is determined by a qualified prescriber based on the patient’s age, weight, renal function and clinical response. Patients should follow the healthcare professional’s instructions.

Safety data for levocetirizine in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levocetirizin is the active enantiomer of cetirizine, offering similar efficacy with a potentially lower incidence of sedation. Compared with first‑generation antihistamines, it provides better selectivity for peripheral H1 receptors and fewer central nervous system effects.

Store Levocetirizin Hexal at ambient temperature, below 25 °C, in the original packaging. Keep the product away from moisture, direct sunlight and heat sources to maintain stability.

Levocetirizin Hexal is taken orally, usually with or without food, as directed by a healthcare professional. Swallow the tablet whole with a glass of water; do not crush or chew unless the product label specifically permits.

Serious but rare risks include angioedema, severe skin reactions such as Stevens‑Johnson syndrome, anaphylaxis, thrombocytopenia, hepatic injury and cardiac arrhythmias. Patients should seek immediate medical attention if they experience swelling of the face or throat, rash, or any signs of an allergic reaction.

Levocetirizin Hexal should be avoided in individuals with known hypersensitivity to levocetirizine or any of the tablet’s excipients. Caution is also advised for patients with severe renal impairment, and it is not recommended for use in children below the age specified in the product labeling without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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