Product image of Levocetirizin Micro Labs (Levocetirizine Dihydrochloride) supplied by GNH India

Levocetirizin Micro Labs

Active Ingredient:
Levocetirizine Dihydrochloride
Origin:
EU

Levocetirizin Micro Labs (Levocetirizine Dihydrochloride)

Levocetirizine Dihydrochloride, the active ingredient in Levocetirizin Micro Labs, is a second‑generation antihistamine presented as an oral formulation for oral use. It is used to relieve symptoms of allergic rhinitis and chronic idiopathic urticaria in adults and children.

GNH India supplies Levocetirizin Micro Labs as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑compliant documentation for global distribution.

Manufacturer / TM Owner

Micro Labs Gmbh

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Indications & Clinical Uses

Levocetirizine is a second‑generation antihistamine that targets histamine‑mediated allergic conditions.

  • Allergic rhinitis: reduces nasal congestion, sneezing, itching and rhinorrhea.
  • Chronic idiopathic urticaria: alleviates wheal formation and itching.
  • Seasonal allergic rhinitis: controls symptoms triggered by pollen exposure.

How It Works

  • Levocetirizine acts as a selective peripheral H1‑receptor antagonist. By binding to H1 receptors on mast cells, basophils and other target cells, it blocks the action of histamine released during allergic reactions, thereby preventing the cascade that leads to vasodilation, increased vascular permeability, and sensory nerve stimulation responsible for typical allergy symptoms.

Side Effects

Levocetirizine may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Drowsiness: mild sedation that may affect alertness.
  • Dry mouth: reduced salivation causing throat discomfort.
  • Headache: transient cranial pain.
  • Fatigue: general feeling of tiredness.
  • Nausea: mild gastrointestinal upset.
  • Dizziness: occasional light‑headed sensation.

Serious or Rare Side Effects

  • Angioedema: swelling of face, lips or tongue requiring urgent care.
  • Anaphylactic reaction: severe systemic allergy with respiratory compromise.
  • Stevens‑Johnson syndrome: rare skin eruption with blistering.
  • Hepatic dysfunction: abnormal liver enzyme elevations.
  • Cardiac arrhythmia: uncommon but reported in susceptible individuals.

Precautions & Warnings

Before initiating Levocetirizine therapy, consider the following precautions.

  • Pregnancy: use only if clearly needed and prescribed by a healthcare professional.
  • Breastfeeding: assess risk versus benefit with a physician.
  • Renal impairment: dosage may require adjustment in patients with reduced kidney function.
  • Elderly patients: monitor for increased sedation or dizziness.
  • Concomitant CNS depressants: may enhance drowsiness, use with caution.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Levocetirizine can interact with other medicines; notable interactions are grouped by clinical significance.

Major Interactions (Avoid)

  • Ketoconazole: may increase Levocetirizine plasma concentrations.
  • Erythromycin: can raise drug levels and risk of side effects.
  • Ritonavir: potent CYP3A4 inhibitor that may elevate exposure.

Moderate Interactions (Monitor Closely)

  • Alcohol: additive sedative effect, caution advised.
  • Other antihistamines: may cause excessive antihistaminic activity.
  • Theophylline: possible increase in theophylline plasma levels.

Frequently Asked Questions

Levocetirizin Micro Labs contains levocetirizine, a second‑generation antihistamine indicated for the relief of symptoms associated with allergic rhinitis and chronic idiopathic urticaria. It helps reduce nasal congestion, sneezing, itching, and hives, improving quality of life for patients with these allergic conditions.

Levocetirizine works by selectively blocking peripheral H1 histamine receptors. By preventing histamine from binding to these receptors on mast cells and other cells, it stops the cascade that leads to vasodilation, increased vascular permeability, and nerve stimulation, thereby reducing the classic signs of an allergic response.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, weight, renal function and clinical response. Physicians typically start with the recommended adult or pediatric dose and may adjust it as needed, but exact dosing regimens should not be inferred without a prescription.

Safety data are limited; therefore, levocetirizine should only be used during pregnancy or lactation if the potential benefit justifies the potential risk to the fetus or infant. Patients who are pregnant, planning pregnancy, or breastfeeding should discuss individual risk factors with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and assistance with import documentation.

Levocetirizine is the active enantiomer of cetirizine and offers similar efficacy with a lower incidence of sedation compared with first‑generation antihistamines such as diphenhydramine. Compared with cetirizine, levocetirizine may provide faster onset of action and improved symptom control in some patients, while maintaining a favorable safety profile.

Store the product at ambient temperature, preferably below 25 °C, in its original packaging. Protect it from moisture, direct sunlight and excessive heat. Keep the container tightly closed and out of reach of children. No refrigeration is required for this oral formulation.

The medication is taken orally, usually with a glass of water. It can be taken with or without food, according to the prescriber’s instructions. Patients should swallow the tablet whole and avoid crushing or chewing unless the formulation specifically permits it.

While generally well tolerated, the most serious adverse events include angioedema, anaphylactic reactions and rare severe skin disorders such as Stevens‑Johnson syndrome. Any signs of swelling of the face, lips, tongue, difficulty breathing, or widespread rash should prompt immediate medical attention.

Levocetirizine is contraindicated in individuals with known hypersensitivity to levocetirizine, cetirizine or any other component of the formulation. Caution is also advised for patients with severe renal impairment, as dose adjustment may be required, and for those taking other sedating medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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