Product image of Levocetirizin Stada (Levocetirizine Dihydrochloride) supplied by GNH India

Levocetirizin Stada

Active Ingredient:
Levocetirizine Dihydrochloride
Origin:
EU

Levocetirizin Stada (Levocetirizine Dihydrochloride)

Levocetirizine, the active ingredient in Levocetirizin Stada, is a H1 receptor antagonist presented as an oral tablet for oral use. It is indicated for the relief of symptoms associated with allergic rhinitis and chronic urticaria in adults and children when appropriate.
GNH India supplies Levocetirizin Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Gmbh

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Indications & Clinical Uses

Levocetirizin Stada is an antihistamine that acts on the H1‑mediated allergic pathway.

  • Allergic rhinitis: reduces sneezing, nasal itching, and rhinorrhea.
  • Seasonal allergic rhinitis: alleviates symptoms triggered by pollen or other seasonal allergens.
  • Chronic urticaria: diminishes the frequency and severity of hives and associated itching.

How It Works

  • Levocetirizine selectively blocks peripheral histamine H1 receptors, preventing histamine from binding and activating the cascade that leads to vasodilation, increased vascular permeability, and sensory nerve stimulation. By inhibiting this receptor, the drug reduces the classic signs of allergic inflammation without crossing the blood‑brain barrier in significant amounts, limiting central nervous system effects.

Side Effects

Levocetirizin Stada is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Drowsiness: mild to moderate sleepiness, especially after the first dose.
  • Fatigue: a feeling of reduced energy or tiredness.
  • Dry mouth: decreased salivation leading to a dry oral cavity.
  • Headache: mild to moderate head discomfort.
  • Nausea: occasional stomach upset or queasiness.
  • Altered taste: transient metallic or bitter sensation.

Serious or Rare Side Effects

  • Angioedema: swelling of face, lips, tongue, or throat requiring urgent care.
  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Anaphylaxis: rapid onset of systemic allergic response.
  • Thrombocytopenia: unusually low platelet count.
  • Hepatic dysfunction: abnormal liver enzyme elevations.
  • Cardiac arrhythmia: rare irregular heart rhythm events.

Precautions & Warnings

Before initiating therapy, clinicians should consider several safety aspects.

  • Renal function assessment: dose adjustment may be needed in impaired clearance.
  • Monitor drowsiness: advise patients about potential sedation, especially when driving.
  • Avoid alcohol: concurrent intake can intensify central nervous system depression.
  • Pregnancy caution: use only if the potential benefit outweighs risk, after professional evaluation.
  • Review concomitant CNS depressants: assess additive sedative effects.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Levocetirizin Stada may interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may raise levocetirizine plasma levels.
  • Other H1 antihistamines: concurrent use can increase anticholinergic burden.

Moderate Interactions (Monitor Closely)

  • Alcohol and sedative agents: can enhance drowsiness.
  • Theophylline: may modestly increase the risk of central nervous system effects.
  • Warfarin: occasional reports of altered INR; monitor coagulation parameters if combined.

Frequently Asked Questions

Levocetirizin Stada is prescribed to manage symptoms of allergic rhinitis, including seasonal and perennial forms, as well as chronic urticaria (hives). By blocking H1 histamine receptors, it helps reduce sneezing, nasal congestion, itching, and the frequency of hives, providing relief for patients with these allergic conditions.

Levocetirizine is a selective antagonist of peripheral H1 histamine receptors. It prevents histamine released during allergic reactions from binding to these receptors, thereby inhibiting the cascade that leads to vasodilation, increased vascular permeability, and sensory nerve activation. This results in decreased inflammation and relief of allergy‑related symptoms.

The appropriate dose of Levocetirizin Stada is determined by the prescribing healthcare professional based on the patient’s age, renal function, and severity of symptoms. Dosage recommendations are provided in the product labeling, and the prescriber will tailor the regimen to each individual’s clinical needs.

Safety data for levocetirizine in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider after a thorough risk‑benefit assessment.

To request Levocetirizin Stada, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Levocetirizin Stada is the active enantiomer of cetirizine, offering a more selective H1‑receptor blockade and often a lower incidence of sedation compared with first‑generation antihistamines. Compared with other second‑generation agents, its efficacy in allergic rhinitis and urticaria is comparable, while its safety profile remains favorable for most patients.

Levocetirizin Stada should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keeping the product in a dry, cool place helps maintain its potency and ensures the tablet’s integrity throughout its shelf life.

Levocetirizin Stada is taken orally, usually as a tablet, with or without food. The tablet should be swallowed whole with a glass of water. Patients should follow the dosing instructions provided by their prescriber and not alter the regimen without medical advice.

While generally well tolerated, serious adverse events can include angioedema, severe skin reactions such as Stevens‑Johnson syndrome, anaphylaxis, thrombocytopenia, and hepatic dysfunction. Patients should seek immediate medical attention if they experience swelling of the face or throat, rash, or any signs of an allergic emergency.

Levocetirizin Stada is contraindicated in individuals with known hypersensitivity to levocetirizine or any of the tablet’s excipients. Caution is advised for patients with severe renal impairment, and it should be avoided in pregnancy or lactation unless clearly indicated by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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