Product image of Levocetirizina Eg (Levocetirizine Dihydrochloride) supplied by GNH India

Levocetirizina Eg

Active Ingredient:
Levocetirizine Dihydrochloride
Origin:
EU

Levocetirizina Eg (Levocetirizine Dihydrochloride)

Levocetirizine, the active ingredient in Levocetirizina Eg, is a antihistamine presented as an oral tablet for oral use. It treats allergic rhinitis and chronic idiopathic urticaria in adults and children.

GNH India supplies Levocetirizina Eg as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eg S.P.A.

1
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Indications & Clinical Uses

  • Levocetirizine is an antihistamine that acts on the histamine H1‑receptor pathway to relieve allergic conditions.
  • Allergic rhinitis: reduces nasal congestion, sneezing, itching and watery discharge.
  • Chronic idiopathic urticaria: alleviates hives and associated itching.
  • Seasonal allergic conjunctivitis: helps lessen eye itching and redness.

How It Works

  • Levocetirizine selectively blocks peripheral H1 histamine receptors, preventing histamine from binding and triggering the cascade that leads to vasodilation, increased vascular permeability, and sensory nerve stimulation. By inhibiting this pathway, the drug reduces the classic signs of allergic inflammation such as itching, swelling, and mucus production.

Side Effects

Levocetirizine is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Drowsiness or fatigue
  • Dry mouth
  • Headache
  • Taste alteration
  • Nausea
  • Mild gastrointestinal discomfort

Serious or Rare Side Effects

  • Angioedema or severe swelling
  • Anaphylactic reactions
  • Stevens‑Johnson syndrome or other severe skin eruptions
  • Rapid heart rate (tachycardia)
  • Hepatic injury
  • Blood dyscrasias such as neutropenia

Precautions & Warnings

  • Use levocetirizine with caution and follow clinical guidance.
  • Renal function assessment: adjust dose in severe renal impairment.
  • Hepatic impairment: monitor liver function before and during therapy.
  • Sedation risk: avoid operating machinery if drowsiness occurs.
  • Pediatric use: not recommended for children under six years of age without specialist advice.
  • Concomitant CNS depressants: monitor for additive sedation.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Levocetirizine may interact with other substances; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Alcohol: can increase sedation and impair cognition.
  • Other antihistamines: additive drowsiness and anticholinergic effects.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may raise plasma concentrations.

Moderate Interactions (Monitor Closely)

  • Theophylline: levocetirizine may increase its plasma levels.
  • Ritonavir or other protease inhibitors: may modestly elevate levocetirizine exposure.
  • Certain antidepressants (e.g., fluoxetine): monitor for enhanced sedation.

Frequently Asked Questions

Levocetirizina Eg contains levocetirizine, which is prescribed to manage allergic rhinitis and chronic idiopathic urticaria. In these conditions, it helps relieve symptoms such as sneezing, nasal congestion, itching, and hives by blocking the action of histamine.

Levocetirizine acts as a selective peripheral H1‑receptor antagonist. By binding to H1 receptors on mast cells and other tissues, it prevents histamine from triggering the inflammatory cascade that causes typical allergy symptoms, thereby reducing swelling, itching, and mucus production.

The appropriate dose of Levocetirizina Eg is determined by the prescribing healthcare professional based on the patient’s age, weight, renal function, and severity of symptoms. Patients should follow the exact regimen provided by their clinician and not adjust the dose on their own.

Safety data for levocetirizine in pregnancy and lactation are limited. Healthcare providers generally weigh the potential benefits against any possible risks before prescribing it to pregnant or nursing women. Patients should discuss their specific situation with a qualified medical professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levocetirizine is the active enantiomer of cetirizine, offering similar efficacy with a potentially lower incidence of sedation. Compared with first‑generation antihistamines, it provides better selectivity for peripheral H1 receptors, resulting in fewer central nervous system effects while maintaining strong allergy control.

Levocetirizina Eg should be stored at temperatures below 25 °C, in its original packaging, and protected from moisture and direct sunlight. Keeping the product in a dry, cool environment helps maintain its stability and potency throughout its shelf life.

The medication is taken orally, usually as a tablet, with or without food as directed by the prescriber. Swallow the tablet whole with a glass of water and avoid crushing or chewing unless specifically instructed.

While uncommon, serious adverse reactions can include angioedema, anaphylaxis, severe skin reactions such as Stevens‑Johnson syndrome, and significant cardiac effects like tachycardia. Patients should seek immediate medical attention if they experience swelling of the face, throat, or any signs of a severe allergic reaction.

Levocetirizina Eg is contraindicated in individuals with known hypersensitivity to levocetirizine or any of its excipients. Caution is advised for patients with severe renal impairment, and it is generally not recommended for children under six years of age without specialist supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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