Product image of Levocetirizina Glenmark (Levocetirizine Dihydrochloride) supplied by GNH India

Levocetirizina Glenmark

Active Ingredient:
Levocetirizine Dihydrochloride
Origin:
EU

Levocetirizina Glenmark (Levocetirizine Dihydrochloride)

Levocetirizine, the active ingredient in Levocetirizina Glenmark, is a second‑generation antihistamine presented as an oral tablet for oral use. It alleviates symptoms of allergic rhinitis and chronic idiopathic urticaria in adults and children when prescribed by a healthcare professional. It is indicated for the relief of itching, sneezing, watery eyes and nasal congestion associated with these conditions.

GNH India supplies Levocetirizina Glenmark as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with capabilities for bulk manufacturing, quality assurance and regulatory compliance.

Manufacturer / TM Owner

Glenmark Arzneimittel Gmbh

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Indications & Clinical Uses

Levocetirizine is a second‑generation antihistamine that reduces histamine‑mediated allergic responses.

  • Allergic rhinitis: reduces sneezing, itching, nasal discharge and congestion.
  • Chronic idiopathic urticaria: relieves hives and associated itching.
  • Seasonal allergic rhinitis: controls symptoms during pollen exposure.

How It Works

  • Levocetirizine selectively blocks peripheral H1 histamine receptors, preventing histamine from binding to mast cells and other target tissues. This inhibition reduces the vascular permeability, sensory nerve activation, and glandular secretions that underlie typical allergic manifestations, thereby providing symptomatic relief without significant central nervous system penetration.

Side Effects

Levocetirizine is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Drowsiness: mild to moderate sleepiness.
  • Dry mouth: reduced salivation.
  • Headache: transient cranial discomfort.
  • Nausea: mild gastrointestinal upset.
  • Fatigue: feeling of reduced energy.
  • Abdominal pain: mild stomach discomfort.

Serious or Rare Side Effects

  • Angioedema: swelling of face, lips or throat.
  • Anaphylaxis: severe, life‑threatening allergic reaction.
  • Stevens‑Johnson syndrome: severe skin eruption.
  • Hepatic enzyme elevation: abnormal liver function tests.
  • Blood dyscrasias: rare blood count abnormalities.
  • Cardiac arrhythmia: irregular heartbeat in susceptible individuals.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Renal or hepatic impairment: adjust dose or monitor closely.
  • Pregnancy: use only if clearly needed after risk assessment.
  • Breastfeeding: evaluate potential exposure to infant.
  • Sedation: avoid operating machinery if drowsiness occurs.
  • Concomitant CNS depressants: monitor for additive sedation.
  • Store at ambient temperature: keep in original packaging, protect from moisture.

Avoid Interactions

Levocetirizine may interact with other medicines; review the following categories.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors: may increase plasma concentrations.
  • Alcohol or CNS depressants: can enhance drowsiness.
  • Other antihistamines: additive sedation risk.

Moderate Interactions (Monitor Closely)

  • Theophylline: may raise levocetirizine levels.
  • Ritonavir: potential increase in exposure.
  • Diuretics: may affect drug elimination.

Frequently Asked Questions

Levocetirizina Glenmark contains levocetirizine, a second‑generation antihistamine indicated for the symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria. It helps relieve sneezing, itching, watery eyes, nasal congestion and hives when prescribed by a qualified healthcare professional.

Levocetirizine works by selectively binding to peripheral H1 histamine receptors, blocking histamine from triggering the cascade that leads to allergic symptoms. This antagonism reduces vascular leakage, nerve activation and glandular secretions, providing relief without significant sedation because it does not readily cross the blood‑brain barrier.

The appropriate dose of Levocetirizina Glenmark is determined by the prescribing clinician based on the patient’s age, condition severity, renal function and other individual factors. Patients should follow the prescriber’s instructions and not adjust the dose without medical advice.

Safety data for levocetirizine during pregnancy and lactation are limited. It should only be used when the potential benefit outweighs any possible risk to the fetus or infant, and the decision should be made by a healthcare professional after a thorough risk‑benefit assessment.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Levocetirizina is a second‑generation H1‑receptor antagonist, offering effective allergy relief with a lower incidence of sedation compared with first‑generation antihistamines such as diphenhydramine. Its rapid onset and once‑daily dosing make it convenient, while its selectivity reduces central nervous system effects seen with older agents.

Store the product at ambient temperature, preferably below 25 °C, in the original container to protect it from moisture and light. Keep the packaging tightly closed and out of reach of children. Do not use the medication after the expiry date printed on the label.

Levocetirizina Glenmark is taken orally, usually as a tablet, with or without food as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed by a healthcare professional.

Although rare, serious adverse reactions can include angioedema, anaphylaxis, severe skin reactions such as Stevens‑Johnson syndrome, significant liver enzyme elevations and cardiac arrhythmias. Patients should seek immediate medical attention if they experience swelling of the face or throat, rash, difficulty breathing, or unexplained heart palpitations.

Levocetirizina should be avoided in individuals with known hypersensitivity to levocetirizine or any excipients in the formulation. Caution is advised for patients with severe renal impairment, uncontrolled asthma, or those taking medications that may cause significant drug‑drug interactions. Pregnant or breastfeeding women should only use it under medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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