Product image of Levocetirizina Stada (Levocetirizine) supplied by GNH India

Levocetirizina Stada

Active Ingredient:
Levocetirizine
Origin:
EU

Levocetirizina Stada (Levocetirizine)

Levocetirizine, the active ingredient in Levocetirizina Stada, is a H1 receptor antagonist presented as an oral dosage form for oral use. It alleviates symptoms of allergic rhinitis and chronic idiopathic urticaria in adults and adolescents.
GNH India supplies Levocetirizina Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratorio Stada, S.L.

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Indications & Clinical Uses

  • Levocetirizine acts on peripheral H1 histamine receptors to control allergic disease manifestations.
  • Allergic rhinitis: reduces nasal congestion, itching, sneezing and watery discharge.
  • Chronic idiopathic urticaria: diminishes the frequency and severity of hives and associated itching.

How It Works

  • Levocetirizine selectively binds to peripheral H1 histamine receptors, preventing histamine from triggering the cascade that leads to vasodilation, increased vascular permeability, and sensory nerve activation. By blocking this pathway, the drug mitigates the classic signs of allergic inflammation without crossing the blood‑brain barrier in significant amounts, thereby limiting central nervous system effects.

Side Effects

Levocetirizine is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Drowsiness or mild sedation.
  • Dry mouth.
  • Headache.
  • Fatigue.
  • Nausea.

Serious or Rare Side Effects

  • Angioedema or swelling of the face, lips, tongue.
  • Anaphylactic reactions requiring emergency care.
  • Severe skin eruptions such as Stevens‑Johnson syndrome.
  • Thrombocytopenia or significant drop in platelet count.
  • Hepatic enzyme elevations.

Precautions & Warnings

  • Before initiating therapy, consider patient‑specific factors and safety measures.
  • Assess renal function: dose may need adjustment in severe impairment.
  • Use caution in hepatic disease: monitor liver enzymes if clinically indicated.
  • Avoid operating machinery or driving if drowsiness occurs.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Levocetirizine may interact with other medicines that affect its metabolism or enhance sedation.

Major Interactions (Avoid)

  • Ketoconazole: can increase levocetirizine plasma concentrations.
  • Erythromycin: may raise systemic exposure.
  • Ritonavir: potent CYP3A4 inhibition may elevate levels.

Moderate Interactions (Monitor Closely)

  • Alcohol: additive central nervous system depression.
  • Other antihistamines or sedatives: may increase drowsiness.
  • Theophylline: levocetirizine can reduce its clearance, requiring monitoring.

Frequently Asked Questions

Levocetirizina Stada contains levocetirizine and is indicated for the symptomatic relief of allergic rhinitis, including seasonal and perennial forms, as well as for the management of chronic idiopathic urticaria, helping to reduce itching, hives, and related discomfort.

Levocetirizine selectively blocks peripheral H1 histamine receptors, preventing histamine from binding and triggering the cascade that leads to vasodilation, increased vascular permeability, and nerve stimulation. This inhibition reduces the classic signs of allergy such as itching, swelling, and nasal congestion.

The appropriate dose of Levocetirizina Stada is determined by the prescribing healthcare professional based on the patient’s age, clinical condition, and renal function. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for levocetirizine in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Levocetirizina Stada.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Levocetirizine is the active enantiomer of cetirizine, offering similar efficacy with a potentially lower incidence of sedation. Compared with first‑generation antihistamines, it provides better selectivity for peripheral H1 receptors and fewer central nervous system effects, making it a preferred option for many patients.

Store Levocetirizina Stada at room temperature, below 25 °C, in the original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in humid or excessively hot environments.

Levocetirizina Stada is taken orally, usually once daily, with or without food, as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed.

Serious adverse reactions, though rare, include angioedema, anaphylaxis, severe skin reactions such as Stevens‑Johnson syndrome, and significant hematologic changes like thrombocytopenia. Patients should seek immediate medical attention if they experience swelling of the face or throat, rash, or unexplained bruising.

Levocetirizina Stada should be avoided in individuals with known hypersensitivity to levocetirizine or any excipients in the formulation. Caution is advised for patients with severe renal impairment, and it should be used only under medical supervision during pregnancy or lactation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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