Product image of Levocetirizina Teva-Ratiopharm (Levocetirizine Dihydrochloride) supplied by GNH India

Levocetirizina Teva-Ratiopharm

Active Ingredient:
Levocetirizine Dihydrochloride
Origin:
EU

Levocetirizina Teva-Ratiopharm (Levocetirizine Dihydrochloride)

Levocetirizine, the active ingredient in Levocetirizina Teva‑Ratiopharm, is an antihistamine presented as an oral tablet for oral use. It reduces histamine‑mediated symptoms such as sneezing, itching, watery eyes, and hives in patients with allergic rhinitis and chronic idiopathic urticaria, typically in adults and adolescents, and improves overall quality of life.

GNH India supplies Levocetirizina Teva‑Ratiopharm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on quality assurance, regulatory compliance, and reliable logistics across multiple regions.

Manufacturer / TM Owner

Teva Pharma S.L.U.,

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Indications & Clinical Uses

  • Levocetirizine acts on histamine‑mediated allergic pathways to relieve symptoms of common allergic conditions.
  • Allergic rhinitis: alleviates nasal congestion, sneezing, itching and runny nose.
  • Seasonal allergic rhinitis: provides symptom relief during pollen seasons.
  • Chronic idiopathic urticaria: reduces frequency and severity of hives and associated itching.

How It Works

  • Levocetirizine is the active R‑enantiomer of cetirizine. It acts as a selective antagonist of peripheral histamine H1 receptors, preventing histamine from binding and triggering the cascade that leads to vasodilation, increased vascular permeability, and sensory nerve activation. By blocking these receptors, it diminishes the allergic inflammatory response without significant central nervous system penetration. The drug’s high affinity for H1 receptors ensures rapid onset of action and sustained symptom control with once‑daily dosing.

Side Effects

Levocetirizine is generally well tolerated, but several adverse reactions have been reported.

Common Side Effects

  • Drowsiness: mild sedation or sleepiness.
  • Dry mouth: reduced salivation.
  • Headache: mild to moderate head pain.
  • Nausea: upset stomach.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Stevens‑Johnson syndrome: rare skin disorder with blistering.
  • Angioedema: swelling of face, lips, or tongue.

Precautions & Warnings

  • Before initiating therapy, consider the following safety measures.
  • Pregnancy: consult a healthcare provider before use.
  • Breastfeeding: assess risk versus benefit.
  • Renal impairment: dose may need adjustment.
  • Elderly: monitor for increased sedation.
  • Driving: avoid operating machinery if drowsy.
  • Store at room temperature: keep below 25°C, in original packaging, protect from moisture.

Avoid Interactions

Levocetirizine may interact with other medicines; review patient medication lists.

Major Interactions (Avoid)

  • Alcohol: can potentiate sedative effects.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): may raise levocetirizine concentrations.

Moderate Interactions (Monitor Closely)

  • CNS depressants (e.g., benzodiazepines): additive drowsiness.
  • Theophylline: possible reduction in antihistamine efficacy.
  • Anticholinergic agents: may increase dry mouth.

Frequently Asked Questions

Levocetirizina Teva‑Ratiopharm contains levocetirizine, an antihistamine indicated for the relief of symptoms associated with allergic rhinitis and chronic idiopathic urticaria, such as sneezing, itching, watery eyes, and hives.

Levocetirizine selectively blocks peripheral H1 histamine receptors, preventing histamine from binding and triggering the cascade that causes vasodilation, increased vascular permeability, and nerve activation, thereby reducing allergic inflammation and related symptoms.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, condition, renal function and other clinical factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety in pregnancy and lactation has not been definitively established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Levocetirizine is the active R‑enantiomer of cetirizine, offering similar efficacy with a potentially lower incidence of sedation. Compared with first‑generation antihistamines, it has minimal central nervous system penetration, resulting in fewer drowsiness‑related side effects.

Store the tablets at room temperature, preferably below 25 °C, in the original packaging to protect them from moisture and light. Do not refrigerate or freeze the product.

The medication is taken orally, usually as a whole tablet with or without food, according to the prescriber’s directions. Swallow the tablet whole; do not crush or chew unless specifically instructed.

Serious but rare adverse reactions include anaphylaxis, Stevens‑Johnson syndrome, and angioedema. Patients should seek immediate medical attention if they experience symptoms such as difficulty breathing, swelling of the face or throat, or widespread skin rash.

Individuals with known hypersensitivity to levocetirizine or any component of the formulation should avoid the product. Caution is also advised for patients with severe renal impairment, as dose adjustment may be required.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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