Product image of Levocetirizine Arrow (Levocetirizine Dihydrochloride) supplied by GNH India

Levocetirizine Arrow

Active Ingredient:
Levocetirizine Dihydrochloride
Origin:
EU

Levocetirizine Arrow (Levocetirizine Dihydrochloride)

Levocetirizine Dihydrochloride, the active ingredient in Levocetirizine Arrow, is a second‑generation antihistamine presented as an oral dosage form for oral use. It treats allergic rhinitis and chronic idiopathic urticaria in adults and adolescents.
GNH India supplies Levocetirizine Arrow as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Arrow Generiques

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Indications & Clinical Uses

  • Levocetirizine Arrow belongs to the antihistamine class and acts on histamine‑mediated allergic conditions.
  • Allergic rhinitis (including seasonal): reduces nasal congestion, sneezing, itching and rhinorrhea.
  • Chronic idiopathic urticaria: alleviates hives and associated itching.
  • Allergic conjunctivitis: helps relieve eye itching, redness and tearing.

How It Works

  • Levocetirizine selectively blocks peripheral H1 receptors, preventing histamine from binding and triggering the cascade that leads to vasodilation, increased vascular permeability, and bronchial smooth‑muscle contraction. By inhibiting this pathway, it reduces the typical signs and symptoms of allergic reactions without significant central nervous system penetration.

Side Effects

Levocetirizine Arrow may cause adverse reactions that vary in frequency and severity.

Common Side Effects

  • Drowsiness: mild to moderate sleepiness.
  • Headache: transient cranial discomfort.
  • Dry mouth: reduced salivation.
  • Fatigue: general lack of energy.
  • Nausea: mild stomach upset.
  • Abdominal discomfort: mild pain or cramping.

Serious or Rare Side Effects

  • Anaphylaxis: severe, potentially life‑threatening allergic reaction.
  • Stevens‑Johnson syndrome: rare skin blistering disorder.
  • Angioedema: swelling of face, lips or tongue.
  • Hepatic dysfunction: abnormal liver enzyme elevations.
  • Blood dyscrasias: rare blood cell abnormalities.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: discuss potential risks with a physician.
  • Renal impairment: dose may require adjustment in reduced kidney function.
  • Elderly patients: monitor for increased sedation or confusion.
  • Alcohol or CNS depressants: avoid concurrent use to reduce additive drowsiness.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Levocetirizine may interact with other medicines; review the following categories.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors: may raise levocetirizine plasma concentrations.
  • Alcohol or other central nervous system depressants: can enhance sedation.

Moderate Interactions (Monitor Closely)

  • Theophylline: levocetirizine may increase theophylline levels.
  • Ritonavir: may elevate levocetirizine exposure.
  • Anticholinergic agents: additive dry‑mouth effect.

Frequently Asked Questions

Levocetirizine Arrow is indicated for the symptomatic relief of allergic rhinitis, including seasonal forms, and for the treatment of chronic idiopathic urticaria. It helps reduce nasal congestion, sneezing, itching, and hives associated with these allergic conditions.

Levocetirizine acts as a selective peripheral H1‑receptor antagonist. By blocking histamine binding at these receptors, it prevents the cascade that leads to vasodilation, increased vascular permeability, and bronchial smooth‑muscle contraction, thereby alleviating typical allergic symptoms.

The prescribed dose of Levocetirizine Arrow is determined by a qualified healthcare professional based on the patient’s age, condition severity, and renal function. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for Levocetirizine during pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before starting therapy.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levocetirizine is the active enantiomer of cetirizine, offering similar efficacy with a lower incidence of sedation for many patients. Compared with first‑generation antihistamines, it provides effective allergy relief while crossing the blood‑brain barrier to a lesser extent, reducing central side effects.

Store Levocetirizine Arrow at ambient temperature, preferably below 25 °C. Keep the tablets in the original blister pack or container, protect them from moisture, heat and direct sunlight to maintain potency throughout the shelf life.

Levocetirizine Arrow is taken orally, usually with a glass of water. It can be taken with or without food, according to the prescriber’s guidance. Swallow the tablet whole; do not crush or chew unless specifically instructed.

Serious adverse reactions, although rare, include anaphylaxis, Stevens‑Johnson syndrome, angioedema, and significant hepatic dysfunction. Patients should seek immediate medical attention if they experience symptoms such as swelling of the face or throat, rash with blisters, or signs of liver injury.

Levocetirizine Arrow should be avoided in individuals with known hypersensitivity to levocetirizine or any component of the formulation. Caution is also advised for patients with severe renal impairment, as dose adjustment may be required, and for those taking interacting medications listed under major interactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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