Product image of Levocetirizine Dihcl Focus Care (Levocetirizine Dihydrochloride) supplied by GNH India

Levocetirizine Dihcl Focus Care

Active Ingredient:
Levocetirizine Dihydrochloride
Origin:
EU

Levocetirizine Dihcl Focus Care (Levocetirizine Dihydrochloride)

Levocetirizine, the active ingredient in Levocetirizine Dihcl Focus Care, is a second‑generation antihistamine presented as an oral tablet for oral use. It is employed to relieve symptoms of allergic rhinitis and chronic idiopathic urticaria in adults and adolescents.
GNH India supplies Levocetirizine Dihcl Focus Care as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Focus Care Pharmaceuticals B.V.

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Indications & Clinical Uses

Levocetirizine acts on the histamine H1‑receptor pathway to control allergic disorders.

  • Allergic rhinitis: reduces nasal congestion, itching, sneezing and watery discharge.
  • Chronic idiopathic urticaria: diminishes the frequency and severity of hives and associated itching.
  • Allergic conjunctivitis: alleviates eye itching, redness and tearing caused by allergens.

How It Works

  • Levocetirizine selectively blocks peripheral H1‑histamine receptors, preventing histamine from binding and triggering the cascade that leads to vasodilation, increased vascular permeability, and sensory nerve activation. By inhibiting this pathway, it reduces the classic signs of allergic inflammation without significant central nervous system penetration.

Side Effects

Levocetirizine is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Drowsiness: mild to moderate sleepiness, especially after the first dose.
  • Headache: transient tension‑type headache.
  • Dry mouth: reduced salivation causing a dry oral cavity.
  • Fatigue: feeling of reduced energy.

Serious or Rare Side Effects

  • Angioedema: swelling of face, lips or tongue requiring immediate medical attention.
  • Severe rash or Stevens‑Johnson syndrome: widespread skin eruption.
  • Anaphylaxis: rapid onset of systemic allergic reaction.
  • Thrombocytopenia: unusually low platelet count.
  • Elevated liver enzymes: abnormal liver function tests.

Precautions & Warnings

Before using Levocetirizine, consider the following safety measures.

  • Renal impairment: dose may need adjustment in severe kidney disease.
  • Hepatic dysfunction: monitor liver function in patients with liver disease.
  • Elderly patients: increased sensitivity to sedation; start with the lowest effective dose.
  • Concomitant CNS depressants: avoid or monitor for additive drowsiness.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit assessment.
  • Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Levocetirizine may interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Ritonavir: can increase levocetirizine plasma levels, raising risk of side effects.
  • Azithromycin: may potentiate QT‑interval prolongation when combined.

Moderate Interactions (Monitor Closely)

  • Alcohol: may enhance drowsiness and impair coordination.
  • Other antihistamines: additive sedation, especially first‑generation agents.
  • CYP3A4 inhibitors (e.g., ketoconazole): may modestly raise levocetirizine concentrations.

Frequently Asked Questions

Levocetirizine Dihcl Focus Care is prescribed to manage symptoms of allergic rhinitis, chronic idiopathic urticaria, and allergic conjunctivitis. It helps reduce nasal congestion, sneezing, itching, hives, and eye irritation caused by histamine release during allergic reactions.

Levocetirizine works by selectively blocking peripheral H1‑histamine receptors. This prevents histamine from binding to its receptors, thereby inhibiting the cascade that leads to vasodilation, increased vascular permeability, and sensory nerve activation, which are responsible for typical allergy symptoms.

The appropriate dose of Levocetirizine Dihcl Focus Care is determined by the prescribing healthcare professional based on the patient’s age, condition severity, renal function, and other individual factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Levocetirizine should be used during pregnancy or lactation only if the potential benefit justifies the potential risk to the fetus or infant. Healthcare providers will assess the risk‑benefit ratio and may recommend alternative therapies when safer options are available.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Levocetirizine is a second‑generation antihistamine, offering effective allergy relief with a lower incidence of sedation compared with first‑generation agents such as diphenhydramine. Its rapid onset and once‑daily dosing make it convenient, while maintaining a favorable safety profile for most patients.

Store the product at ambient temperature, preferably below 25 °C. Keep it in the original container, protect it from moisture, heat, and direct sunlight. Do not refrigerate or freeze the tablets, and keep them out of reach of children.

Levocetirizine Dihcl Focus Care is taken orally, usually as a whole tablet with or without food. Swallow the tablet with a glass of water. Follow the prescribing clinician’s directions regarding timing and any specific administration instructions.

Serious adverse reactions, though rare, include angioedema, severe skin reactions such as Stevens‑Johnson syndrome, anaphylaxis, thrombocytopenia, and significant liver enzyme elevations. Patients should seek immediate medical attention if they experience swelling of the face or throat, widespread rash, or signs of an allergic shock.

Levocetirizine should be avoided in individuals with known hypersensitivity to levocetirizine or any component of the formulation. Caution is advised for patients with severe renal impairment, uncontrolled hepatic disease, or those taking medications that have major interactions, unless supervised by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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