Levocetirizine Dihydrochloride Activase Pharmaceuticals (Levocetirizine Dihydrochloride)

The drug acts as a selective peripheral H1‑receptor antagonist. By blocking histamine binding at these receptors, it prevents the cascade that leads to vasodilation, increased vascular permeability, and sensory nerve activation, thereby reducing typical allergic signs such as itching, swelling, and nasal congestion.

The appropriate dose is determined by the prescribing healthcare professional based on the patient’s age, condition severity, renal function and other clinical factors. Patients should follow the prescriber’s instructions and not alter the dose without medical advice.

Safety data are limited; therefore, use during pregnancy or while breastfeeding should only occur if the potential benefit justifies the potential risk. Healthcare providers should evaluate each case individually and discuss possible alternatives.

Enquiries are submitted via the product page on gnhindia.com, where you specify the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levocetirizine is the active enantiomer of cetirizine, offering similar efficacy with a potentially lower incidence of sedation. Compared with first‑generation antihistamines, it has a more favorable safety profile and does not readily cross the blood‑brain barrier, reducing central nervous system effects.

Store the oral tablets at ambient temperature, below 25 °C, in the original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight to maintain product stability.

Levocetirizine is taken orally, usually as a tablet, with or without food. The tablet should be swallowed whole with a glass of water. Patients should not crush, chew, or split the tablet unless specifically instructed by a healthcare professional.

Serious adverse reactions, although rare, include angioedema, anaphylaxis, severe skin reactions such as Stevens‑Johnson syndrome, and significant hepatic enzyme elevations. Any signs of swelling, rash, or difficulty breathing require immediate medical attention.

Individuals with known hypersensitivity to levocetirizine, cetirizine or any excipients in the formulation should avoid the drug. Caution is also advised for patients with severe renal impairment, as dose adjustment may be necessary, and for those taking interacting medications listed under major interactions.