Product image of Levocetirizine Eg (Levocetirizine) supplied by GNH India

Levocetirizine Eg

Active Ingredient:
Levocetirizine
Origin:
EU

Levocetirizine Eg (Levocetirizine)

Levocetirizine, the active ingredient in Levocetirizine Eg, is an antihistamine presented as an oral tablet for oral use. It alleviates symptoms of allergic rhinitis and chronic idiopathic urticaria in adults and children when prescribed by a healthcare professional.

GNH India supplies Levocetirizine Eg as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Eg Labo Laboratoires Eurogenerics

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Indications & Clinical Uses

  • Levocetirizine is an antihistamine that targets histamine‑mediated allergic conditions.
  • Allergic rhinitis: reduces nasal congestion, sneezing and itching caused by seasonal or perennial allergens.
  • Chronic idiopathic urticaria: diminishes the frequency and severity of hives and associated itching.
  • Seasonal allergic rhinitis: provides relief from symptoms triggered by pollen or other seasonal allergens.

How It Works

  • Levocetirizine acts as a selective antagonist of peripheral histamine H1 receptors. By binding to these receptors on mast cells, basophils, and sensory nerves, it blocks the action of endogenous histamine released during allergic reactions, thereby preventing the cascade of vascular permeability, edema, and sensory nerve activation that produce typical allergy symptoms.

Side Effects

Levocetirizine is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Drowsiness or mild sedation.
  • Fatigue or feeling of tiredness.
  • Dry mouth.
  • Headache.
  • Nausea.
  • Dizziness.

Serious or Rare Side Effects

  • Angioedema or swelling of the face, lips, tongue.
  • Anaphylactic reactions requiring emergency care.
  • Severe skin reactions such as Stevens‑Johnson syndrome.
  • Hepatic dysfunction or elevated liver enzymes.
  • Cardiac arrhythmias.
  • Hematologic abnormalities like neutropenia.

Precautions & Warnings

  • Before initiating therapy, consider the following precautions.
  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: discuss potential risks with a physician.
  • Renal impairment: dose may need adjustment in reduced kidney function.
  • Elderly patients: monitor for increased sedation or dizziness.
  • Avoid alcohol: may potentiate drowsiness.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Levocetirizine may interact with other medicines; awareness of the interaction level is important.

Major Interactions (Avoid)

  • Ketoconazole: can increase levocetirizine plasma concentrations.
  • Ritonavir: may raise levocetirizine levels, enhancing side effects.
  • Co‑administration with other sedating antihistamines: additive central nervous system depression.

Moderate Interactions (Monitor Closely)

  • Alcohol: may enhance drowsiness and impair coordination.
  • Other CNS depressants (e.g., benzodiazepines): potential additive sedation.
  • Theophylline: may increase the risk of levocetirizine‑related adverse effects.

Frequently Asked Questions

Levocetirizine Eg is prescribed to manage allergic rhinitis, including seasonal and perennial forms, and chronic idiopathic urticaria. It helps relieve nasal congestion, sneezing, itching, and reduces the frequency and severity of hives, providing symptomatic relief for patients with these allergic disorders.

Levocetirizine works by selectively blocking peripheral histamine H1 receptors. By preventing histamine from binding to these receptors on mast cells, basophils, and sensory nerves, it stops the cascade that leads to vascular leakage, edema, and nerve stimulation, thereby reducing allergic symptoms.

The appropriate dose of Levocetirizine Eg is determined by a qualified prescriber based on the patient’s age, weight, renal function, and clinical response. Healthcare professionals tailor the regimen to achieve optimal symptom control while minimizing potential side effects.

Safety data for Levocetirizine Eg in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before starting therapy.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Levocetirizine is the active R‑enantiomer of cetirizine, offering similar efficacy with a potentially lower incidence of sedation. Compared with first‑generation antihistamines, it provides better selectivity for H1 receptors and fewer anticholinergic side effects, making it a preferred option for many patients.

Levocetirizine Eg should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture and direct sunlight to maintain its stability and potency throughout its shelf life.

Levocetirizine Eg is taken orally, usually as a tablet, with or without food. The patient should swallow the tablet whole with a glass of water, following the dosing instructions provided by the prescribing clinician.

Serious adverse reactions, although rare, include angioedema, anaphylaxis, severe skin reactions such as Stevens‑Johnson syndrome, hepatic dysfunction, cardiac arrhythmias, and hematologic abnormalities. Patients should seek immediate medical attention if they experience swelling of the face, lips, tongue, or any signs of a severe allergic reaction.

Levocetirizine Eg is contraindicated in individuals with known hypersensitivity to levocetirizine or any of its excipients. Caution is advised for patients with severe renal impairment, and it should be used under medical supervision in pregnant or breastfeeding women.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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