Product image of Levocetirizine Glenmark (Levocetirizine Dihydrochloride) supplied by GNH India

Levocetirizine Glenmark

Active Ingredient:
Levocetirizine Dihydrochloride
Origin:
EU

Levocetirizine Glenmark (Levocetirizine Dihydrochloride)

Levocetirizine, the active ingredient in Levocetirizine Glenmark, is an antihistamine presented as an oral tablet for oral use. It is indicated for the relief of symptoms associated with allergic rhinitis and chronic idiopathic urticaria in adults and adolescents.

GNH India supplies Levocetirizine Glenmark as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide in accordance with EU quality standards. The company ensures batch‑to‑batch consistency and regulatory compliance for global distribution.

Manufacturer / TM Owner

Glenmark Arzneimittel Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Levocetirizine is an antihistamine that acts on histamine‑mediated allergic pathways.

  • Allergic rhinitis: alleviates sneezing, nasal congestion, itching and rhinorrhea.
  • Chronic idiopathic urticaria: reduces the frequency and severity of hives and itching.

How It Works

  • Levocetirizine selectively blocks peripheral histamine H1 receptors, preventing histamine from binding to its target cells in the nasal mucosa, skin and conjunctiva. By inhibiting this receptor, the drug diminishes vasodilation, increased vascular permeability and sensory nerve activation that underlie allergic symptoms, providing rapid relief without significant anticholinergic activity. The high affinity for the H1 subtype ensures prolonged receptor occupancy, allowing once‑daily dosing and a favorable safety profile compared with first‑generation antihistamines.

Side Effects

Levocetirizine may cause adverse reactions, most of which are mild and transient.

Common Side Effects

  • Headache: mild to moderate headache reported.
  • Drowsiness: transient sleepiness, especially at higher doses.
  • Dry mouth: reduced salivation.
  • Fatigue: feeling of tiredness.
  • Nausea: mild gastrointestinal upset.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Stevens‑Johnson syndrome: rare skin disorder with blistering.
  • Hepatotoxicity: abnormal liver function tests.
  • Cardiac arrhythmia: rare reports of irregular heartbeat.

Precautions & Warnings

Before initiating Levocetirizine, consider the following precautions to ensure safe use.

  • Renal impairment: dose adjustment may be required in patients with reduced kidney function.
  • Hepatic disease: monitor liver function in patients with existing liver disorders.
  • Elderly patients: increased sensitivity to sedative effects; start with lowest effective dose.
  • Concomitant CNS depressants: avoid or monitor for enhanced drowsiness when combined with alcohol or sedatives.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit assessment.
  • Store below 25°C: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Levocetirizine can interact with other medicines; awareness of major and moderate interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Ketoconazole: strong CYP3A4 inhibitor may increase levocetirizine plasma levels.
  • Erythromycin: macrolide antibiotics can raise levocetirizine concentrations.
  • Theophylline: may enhance central nervous system stimulation when combined.

Moderate Interactions (Monitor Closely)

  • Alcohol: can potentiate drowsiness and impair cognition.
  • CNS depressants (benzodiazepines, antihistamines): additive sedative effect.
  • Antacids containing aluminum or magnesium: may reduce absorption slightly.

Frequently Asked Questions

Levocetirizine Glenmark contains the active ingredient levocetirizine dihydrochloride, an oral antihistamine indicated for the symptomatic treatment of allergic rhinitis—including seasonal and perennial forms—and for chronic idiopathic urticaria. It helps relieve nasal congestion, sneezing, itching, and hives by blocking histamine H1 receptors.

Levocetirizine works by selectively antagonizing peripheral histamine H1 receptors. By preventing histamine from binding to these receptors on nasal mucosa, skin, and conjunctiva, it reduces vasodilation, increased vascular permeability, and sensory nerve activation that cause the classic symptoms of allergy, providing rapid relief without significant anticholinergic effects.

The appropriate dose of levocetirizine is determined by the prescribing healthcare professional based on the patient’s age, clinical condition, and renal function. The prescriber will select the strength and dosing frequency that best manages the individual’s allergic symptoms while minimizing potential side effects.

Safety of levocetirizine in pregnancy or while nursing has not been definitively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made in consultation with a qualified healthcare provider.

To order Levocetirizine Glenmark, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. The sales team then provides pricing, availability, shipping details and any required import documentation.

Levocetirizine is a second‑generation antihistamine that offers high selectivity for the H1 receptor and a lower propensity for sedation compared with first‑generation agents such as diphenhydramine. Its once‑daily dosing and rapid onset make it convenient, while maintaining efficacy similar to other second‑generation drugs like cetirizine and fexofenadine.

Levocetirizine Glenmark should be stored below 25 °C in its original container, protected from moisture and direct sunlight. Keeping the product in a dry, temperature‑controlled environment helps maintain its potency and shelf life until the expiry date indicated on the packaging.

Levocetirizine Glenmark is taken orally, usually as a tablet, with or without food. The tablet is swallowed whole with a glass of water. Patients should follow the dosing instructions provided by their prescriber and avoid crushing or chewing the tablet unless otherwise directed.

Although rare, serious adverse reactions to levocetirizine can include anaphylaxis, Stevens‑Johnson syndrome, and significant liver enzyme elevations. Patients should seek immediate medical attention if they experience symptoms such as rash, swelling, difficulty breathing, or jaundice. Prompt reporting allows early management of potentially life‑threatening events.

Levocetirizine should be avoided in individuals with known hypersensitivity to the drug or any of its excipients. Caution is advised for patients with severe renal impairment, as dose adjustment may be required, and for those taking medications that strongly inhibit CYP3A4. Pregnant or breastfeeding women should only use it after a thorough risk‑benefit assessment by their clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.