Product image of Levocetirizine Teva (Levocetirizine Dihydrochloride) supplied by GNH India

Levocetirizine Teva

Active Ingredient:
Levocetirizine Dihydrochloride
Origin:
EU

Levocetirizine Teva (Levocetirizine Dihydrochloride)

Levocetirizine Dihydrochloride, the active ingredient in Levocetirizine Teva, is an antihistamine presented as an oral tablet for systemic use. It treats allergic rhinitis and chronic idiopathic urticaria in adults and adolescents.

GNH India supplies Levocetirizine Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Pharma Belgium N.V./S.A

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Indications & Clinical Uses

  • Levocetirizine Teva is used to manage allergic conditions mediated by histamine H1 receptors.
  • Allergic rhinitis: reduces nasal congestion, sneezing, and itching associated with seasonal or perennial allergies.
  • Chronic idiopathic urticaria: alleviates persistent hives and itching in patients with unexplained chronic urticaria.
  • Allergic conjunctivitis: provides relief of eye itching and redness caused by histamine release.

How It Works

  • Levocetirizine Dihydrochloride selectively blocks peripheral histamine H1 receptors, preventing histamine from binding to mast cells and basophils. By inhibiting this receptor, it reduces vascular permeability, nerve stimulation, and inflammatory responses that cause the symptoms of allergic reactions. The high affinity for the H1 receptor provides rapid onset of action and a prolonged duration, allowing once‑daily dosing.

Side Effects

Levocetirizine may cause adverse reactions, which are generally mild but can be serious in rare cases.

Common Side Effects

  • Headache: mild to moderate headache.
  • Dry mouth: sensation of oral dryness.
  • Drowsiness: mild sedation, especially at treatment start.
  • Nausea: mild gastrointestinal upset.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring emergency care.
  • Stevens‑Johnson syndrome: rare severe skin reaction.
  • Thrombocytopenia: significant drop in platelet count.
  • Hepatic dysfunction: elevated liver enzymes indicating liver stress.

Precautions & Warnings

Before initiating therapy, consider the following precautions.

  • Pregnancy: safety not established; use only if clearly needed.
  • Breastfeeding: assess risk versus benefit before use.
  • Renal impairment: dose adjustment may be required; monitor renal function.
  • Elderly: increased sensitivity to sedative effects; start with lowest effective dose.
  • Concomitant CNS depressants: may enhance drowsiness; monitor patient.
  • Store at ambient temperature: keep below 25 °C, protect from moisture and light in original packaging.

Avoid Interactions

Levocetirizine can interact with other medicines; review patient medication lists.

Major Interactions (Avoid)

  • Alcohol: may potentiate drowsiness and impair cognition.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole): can increase levocetirizine plasma levels.
  • Monoamine oxidase inhibitors: risk of additive antihistaminic effects.

Moderate Interactions (Monitor Closely)

  • CNS depressants (e.g., benzodiazepines): may increase sedation.
  • Other antihistamines: additive antihistaminic effect, risk of excessive sedation.
  • Ritonavir: may modestly raise levocetirizine concentrations.

Frequently Asked Questions

Levocetirizine Teva is an oral antihistamine indicated for the relief of symptoms associated with allergic rhinitis, such as sneezing, nasal congestion, and itching, as well as for the treatment of chronic idiopathic urticaria, helping to reduce persistent hives and itching.

Levocetirizine works by selectively antagonizing peripheral histamine H1 receptors. By blocking these receptors, it prevents histamine‑mediated vascular leakage, nerve stimulation, and inflammatory responses that produce the characteristic signs of allergic reactions.

The prescribed dose of Levocetirizine Teva is determined by the treating healthcare professional based on the patient’s age, condition, and renal function. Typically, adults receive a once‑daily oral dose, but exact dosing should follow the prescriber’s instructions.

Safety data for Levocetirizine during pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision should be made in consultation with a qualified healthcare provider.

To order Levocetirizine Teva, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Levocetirizine is the active enantiomer of cetirizine, offering higher affinity for the H1 receptor and often a lower incidence of sedation. Compared with first‑generation antihistamines, it provides effective symptom control with fewer central nervous system effects, making it a preferred option for many patients.

Levocetirizine Teva tablets should be stored at ambient temperature, below 25 °C, in their original packaging to protect from moisture and light. Keep the product out of reach of children and avoid exposure to extreme temperatures or humidity.

Levocetirizine Teva is taken orally, usually as a whole tablet with or without food. Swallow the tablet whole with a glass of water; do not crush, chew, or split the tablet unless specifically instructed by a healthcare professional.

Serious risks, although rare, include anaphylactic reactions, severe skin disorders such as Stevens‑Johnson syndrome or toxic epidermal necrolysis, significant thrombocytopenia, and hepatic dysfunction. Patients should seek immediate medical attention if they experience signs of these conditions.

Levocetirizine Teva should be avoided in individuals with known hypersensitivity to levocetirizine, other piperazine antihistamines, or any of the excipients in the tablet. Caution is also advised for patients with severe renal impairment, pregnant or nursing women, and those taking interacting medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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