Levocetirizine Zentiva (Levocetirizine Dihydrochloride)

Levocetirizine works by selectively blocking peripheral H1 histamine receptors. This prevents histamine‑mediated vasodilation, increased vascular permeability, and nerve stimulation, thereby diminishing the early and late phases of the allergic response.

The prescribed dose is determined by the treating clinician based on the patient’s age, condition and renal function. In many adult patients a single 5 mg tablet once daily is common, but the exact regimen must be set by a qualified healthcare professional.

Safety data in pregnancy and lactation are limited. Levocetirizine should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made in consultation with a physician.

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Levocetirizine is the active enantiomer of cetirizine and generally provides similar antihistaminic efficacy with a lower incidence of sedation. Both belong to the second‑generation antihistamine class, but levocetirizine may be preferred when a reduced drowsiness profile is desired.

Store the tablets at room temperature, below 25 °C, in the original blister pack or container. Protect them from moisture, excessive heat and direct sunlight to maintain product stability.

The medication is taken orally, usually as a whole tablet swallowed with a glass of water. It can be taken with or without food, according to the prescriber’s instructions.

Serious adverse reactions, although rare, include angioedema, anaphylactic shock and severe cutaneous adverse reactions such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience swelling of the face, lips or throat, or a widespread rash.

Individuals with known hypersensitivity to levocetirizine or any excipients in the tablet should avoid it. Caution is also advised for patients with severe renal impairment, as dose adjustment may be required, and for those taking interacting medications listed under major interactions.