Product image of Levodrix (Levodropropizine) supplied by GNH India

Levodrix

Active Ingredient:
Levodropropizine
Origin:
EU

Levodrix (Levodropropizine)

Levodropropizine, the active ingredient in Levodrix, is an antitussive presented as an oral formulation for oral use. It reduces the frequency and intensity of dry, non‑productive coughs in both adults and children by acting on peripheral cough receptors of the respiratory tract.

GNH India supplies Levodrix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and health‑care institutions worldwide, with a focus on quality assurance, regulatory compliance and reliable logistics. Our distribution network ensures timely delivery across the EU and other markets.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

  • Levodropropizine, marketed as Levodrix, is used to suppress coughs that arise from irritation of the respiratory tract.
  • Dry cough: reduces the frequency and severity of a dry, tickling cough without producing mucus.
  • Non‑productive cough: alleviates coughing that does not generate sputum, improving comfort.
  • Cough associated with viral respiratory infection: helps control cough symptoms during common colds or mild flu episodes.

How It Works

  • Levodropropizine acts peripherally on sensory nerve endings in the respiratory tract, decreasing the sensitivity of the cough reflex. By inhibiting afferent signals from cough receptors, it reduces the urge to cough without affecting central nervous system pathways, providing symptom relief while preserving normal protective reflexes.

Side Effects

Levodropropizine is generally well tolerated, but some patients may experience adverse reactions.

Common Side Effects

  • Nausea: mild stomach upset that may resolve with continued use.
  • Headache: transient mild to moderate headache.
  • Dizziness: occasional light‑headed sensation.
  • Abdominal discomfort: mild pain or cramping in the stomach area.

Serious or Rare Side Effects

  • Allergic reactions: rash, itching, or swelling that may require medical attention.
  • Angioedema: swelling of the face, lips, tongue, or throat.
  • Hepatic dysfunction: signs of liver injury such as jaundice or elevated liver enzymes.

Precautions & Warnings

  • Before using Levodrix, consider the following safety measures.
  • Assess patient history: verify no known hypersensitivity to levodropropizine.
  • Monitor hepatic function: use caution in patients with liver impairment.
  • Avoid concomitant use with other potent antitussives unless advised.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Levodropropizine may interact with other medicines; review the following categories.

Major Interactions (Avoid)

  • Concurrent use with monoamine oxidase inhibitors (MAOIs): risk of unknown pharmacodynamic interaction.
  • Co‑administration with other potent antitussives: may increase risk of excessive cough suppression.
  • Use with drugs that prolong the QT interval: potential additive cardiac risk.

Moderate Interactions (Monitor Closely)

  • Combination with sedatives or antihistamines: may enhance drowsiness.
  • Concurrent use with hepatic enzyme inhibitors: may increase plasma levels of levodropropizine.
  • Co‑administration with CYP2D6 substrates: possible altered metabolism.

Frequently Asked Questions

Levodrix contains levodropropizine, an antitussive that is indicated for the symptomatic relief of dry and non‑productive coughs. It is used in both adult and pediatric patients to reduce coughing frequency and improve comfort during respiratory infections.

Levodropropizine works peripherally by inhibiting sensory nerve endings in the respiratory tract. This reduces the sensitivity of the cough reflex, lowering the urge to cough without acting on central nervous system pathways, thereby providing symptom relief while preserving protective airway reflexes.

The appropriate dose of Levodrix is determined by the prescribing healthcare professional based on the patient’s age, weight, and clinical condition. Dosage recommendations are provided in the product’s prescribing information and should not be altered without medical guidance.

Safety data for levodropropizine in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Levodrix.

To place an enquiry, visit the product page for Levodrix on gnhindia.com and submit the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Levodrix (levodropropizine) is a peripheral antitussive, whereas agents like codeine or dextromethorphan act centrally on the brain’s cough centre. Peripheral agents tend to have fewer central nervous system side effects such as sedation, making Levodrix a suitable alternative for patients who require cough relief without central effects.

Levodrix should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Levodrix is taken orally, usually with a glass of water. The tablet or liquid form should be swallowed whole unless the prescribing information advises otherwise. It can be taken with or without food, depending on the prescriber’s instructions.

Serious adverse reactions, although rare, include allergic responses such as rash, itching, swelling, or angioedema, and signs of hepatic dysfunction like jaundice. Patients should seek immediate medical attention if they experience any of these symptoms.

Levodrix should be avoided in individuals with a known hypersensitivity to levodropropizine or any excipients in the formulation. It is also contraindicated in patients with severe liver disease or in those for whom a central cough suppressant is medically required without professional guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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